BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0126.p (331 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC1568 [V] COG1680 Beta-lactamase class C and other penicillin b... 179 7e-45 CC1567 [V] COG1680 Beta-lactamase class C and other penicillin b... 167 2e-41 CC3190 [V] COG1680 Beta-lactamase class C and other penicillin b... 164 2e-40 CC3628 [V] COG1680 Beta-lactamase class C and other penicillin b... 149 1e-35 MT1414 [V] COG1680 Beta-lactamase class C and other penicillin b... 136 6e-32 >CC1568 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 436 Score = 179 bits (454), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 116/331 (35%), Positives = 175/331 (52%), Gaps = 33/331 (9%) Query: 3 SFRLTCAAVVAAVVLAA---PAFSHTEGTYEI---PAGAHFNSAKLARISEFFKNEVATG 56 +FR AA A++LA+ A++ T+ + P F++ L ++ + V G Sbjct: 2 AFRKWVAASAVAMLLASGASAAWAETKAPAIVAAAPESVGFSAEGLKKLDAHMQGLVDKG 61 Query: 57 KIPGAIVLIQQHGKPVYHEAFGVQDVVSKVPITDKTIFRLASMSKSITAVVSMQLLQEGK 116 +PG ++ +HGK V + G + P+T T+FR+ S +K +T V M L +EGK Sbjct: 62 HLPGVTTMLVRHGKVVNFQVHGKKGF-DGPPMTKDTVFRIYSQTKPVTGVAMMILFEEGK 120 Query: 117 YKLDDPVSKYIPSFANVKVGVEKKAEDGTKTLELVPPKRPITILDLMTHTSGITYGFYGD 176 + LDDPVSK+IP FAN++V K + + + VP +RP T+ +LM+H++G YG D Sbjct: 121 WTLDDPVSKFIPEFANLRV---LKGVNADGSFDTVPAERPPTMRELMSHSAGFAYGLTPD 177 Query: 177 SLVRKTYKEANIYGGDFDLAEFAERIAKLPLHNQPGALWQYGHSTDILARVMEVTTGEKL 236 + + K Y + + G A+F + IA++PL +QPG W+Y + DI ++E TG L Sbjct: 178 NPLDKAYADKVL--GARSRADFVKAIAEIPLVDQPGKRWKYSIAVDIQGLIVEKLTGLSL 235 Query: 237 STIERERLLDPLGMKDTGF-------------FVTDPEKQKLMAEPMPNDSDFRVGRVND 283 + R+ DPL MKDTGF +V P+ KL +P D V D Sbjct: 236 GDFMKSRIFDPLKMKDTGFWLPAEKADRLASLYVWSPKVNKL----VPADGYM----VLD 287 Query: 284 PTKVKKWESASGGMVSTMADYSRFAQMLXSA 314 TK S GG+VST ADY+RFAQML + Sbjct: 288 ITKPPAMASGGGGLVSTNADYARFAQMLLNG 318 >CC1567 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 490 Score = 167 bits (424), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 100/291 (34%), Positives = 156/291 (53%), Gaps = 20/291 (6%) Query: 32 PAGAHFNSAKLARISEFFKNEVATGKIPGAIVLIQQHGKPVYHEAFGVQDVVSKVPITDK 91 P F++ +L R+ + + V G+I G + ++ +HG+ V AFG + V+ P+ Sbjct: 64 PEEGGFSAERLKRLDDHMQTMVDRGQIAGGVTVLARHGRVVQARAFG-RRVLGGDPMPMD 122 Query: 92 TIFRLASMSKSITAVVSMQLLQEGKYKLDDPVSKYIPSFANVKVGVEKKAEDGTKTLELV 151 IFR+ S +K +T V M L ++G ++LDDPVS +IP FAN++V K D T L Sbjct: 123 AIFRIRSETKPVTGVAMMMLYEQGLWRLDDPVSLHIPEFANLRV---AKGVDETGQPILT 179 Query: 152 PPKRPITILDLMTHTSGITYGFYGD--SLVRKTYKEANIYGGDFDLAEFAERIAKLPLHN 209 P R T+ +LMTHT+G YG D S + Y A + L + ++++ LP+ Sbjct: 180 PVSRSPTMRELMTHTAGFAYGLANDPSSPADQAYYRAEVLQ-SASLTDLVQKVSGLPMFA 238 Query: 210 QPGALWQYGHSTDILARVMEVTTGEKLSTIERERLLDPLGMKDTGFFVTDPEKQKLMAEP 269 +PG LW+Y + DI ++E +G+ L +ER+ PLGMKDT F+V + ++ +L A Sbjct: 239 EPGQLWRYSVAADIQGYIVEKLSGQSLPVFMQERIFTPLGMKDTAFYVPEEKQARLAAL- 297 Query: 270 MPNDSDFRVGRVNDPTKVKKWESAS---------GGMVSTMADYSRFAQML 311 D D G++ P W S GG+VST D++RFAQM+ Sbjct: 298 --YDGDPATGQLV-PAVEGAWRDVSKPPAAPLGGGGLVSTAGDFARFAQMI 345 >CC3190 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 490 Score = 164 bits (416), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 99/295 (33%), Positives = 156/295 (52%), Gaps = 13/295 (4%) Query: 28 TYEIPAGAHFNSAKLARISEFFKNE-VATGKIPGAIVLIQQHGKPVYHEAFGVQDVVSKV 86 T P +S +L RI F + + + TGK+P A+ + + G+ + G DV Sbjct: 82 TMSTPEAVGLSSERLKRIDSFIQAKYIDTGKLPCALTQVWRRGQLAHTSVLGSADVERGK 141 Query: 87 PITDKTIFRLASMSKSITAVVSMQLLQEGKYKLDDPVSKYIPSFANVKVGVEKKAEDGTK 146 P+ ++FR+ SM+K IT+V M L++EG LDDPV ++IP++ + +GV + G Sbjct: 142 PLKADSLFRIYSMTKPITSVAFMMLVEEGLASLDDPVHRFIPAWRD--IGVFQAGVAG-- 197 Query: 147 TLELVPPKRPITILDLMTHTSGITYGFYGDSLVRKTYKEANIYGGDFD--LAEFAERIAK 204 + K P+ +DL+ HTSG+TYGF + V Y++ + G D + L F E + Sbjct: 198 AFQTTRTKEPMRTIDLLRHTSGLTYGFQQRTNVDAAYRKLKLDGVDSEGGLKTFVETLGT 257 Query: 205 LPLHNQPGALWQYGHSTDILARVMEVTTGEKLSTIERERLLDPLGMKDTGFFVTDPEKQK 264 +PL PG W Y +TD+L ++EV +G + R+ DPL M DTGFFV + ++++ Sbjct: 258 VPLEFSPGEAWNYSVATDVLGYLVEVISGMPFDVFLKTRIFDPLKMVDTGFFVPEGQRER 317 Query: 265 LMAEPMPNDSDFRVGRVNDPTKVKKW-----ESASGGMVSTMADYSRFAQMLXSA 314 A S +V +DP K + +S GG+VST DY RF +ML + Sbjct: 318 FTACYALTPSG-KVVLQDDPEKSRYLSDPSVKSGGGGLVSTADDYMRFCRMLLNG 371 >CC3628 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 479 Score = 149 bits (375), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 88/279 (31%), Positives = 148/279 (53%), Gaps = 23/279 (8%) Query: 43 ARISEFFKNEVATGKIPGAIVLIQQHGKPVYHEAFGVQDVVSKVPITDKTIFRLASMSKS 102 ARI+ K V +G+ G L+ Q G+ Y G+ D + P+ + ++ SM+K Sbjct: 95 ARINAALKAMVDSGRAAGVSALVWQGGQERYFGVAGMADREAGKPMDRSALVQIFSMTKP 154 Query: 103 ITAVVSMQLLQEGKYKLDDPVSKYIPSFANVKVGVEKKAEDGTKTLELVPPKRPITILDL 162 +T V MQL ++GK+ LDDP+++Y+P FA++KV DG + P RPI + D+ Sbjct: 155 VTGVALMQLWEQGKFGLDDPLARYLPEFADMKV------SDGQGGVR--PAARPILVRDI 206 Query: 163 MTHTSGITYGFYGDSLVRKTYKEANIYGGDFDLAEFAERIAKLPLHNQPGALWQYGHSTD 222 + HT+G +YG +G+ ++ A+ + DLAEF R+A PL PG W Y + D Sbjct: 207 LRHTAGFSYG-WGEGPADAAFRAADPLNLNNDLAEFGRRLATAPLLYDPGERWSYSAAVD 265 Query: 223 ILARVMEVTTGEKLSTIERERLLDPLGMKDTGFFVTDPEK---------QKLMAEPMPND 273 + A ++E +G+ T + +L+PLGM+ T + T PE ++ + Sbjct: 266 VQALLVERLSGQPFETYVKANVLEPLGMRTTAW--TQPEAAFAGLAATYRRGADGKLARQ 323 Query: 274 SDFRVGRVN-DPTKVKKWESASGGMVSTMADYSRFAQML 311 D R+N DP+ ++ G+V+++ DY+RF++ML Sbjct: 324 DDVVTRRMNFDPS--RRLTMGGAGLVASIDDYARFSRML 360 >MT1414 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins MtC Mycobacterium tuberculosis CDC1551 Length = 401 Score = 136 bits (343), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 88/260 (33%), Positives = 133/260 (51%), Gaps = 13/260 (5%) Query: 56 GKIPGAIVLIQQHGKPVYHEAFGVQDVVSKVPITDKTIFRLASMSKSITAVVSMQLLQEG 115 G + GA+ ++ Q K + G +D+ + VP+ T+FR+ASM+K +T +M L+ EG Sbjct: 17 GLLSGAVTMVWQREKLLQVNEIGYRDIDAGVPMQRDTLFRIASMTKPVTVAAAMSLVDEG 76 Query: 116 KYKLDDPVSKYIPSFANVKVGVEKKAEDGTKTLELV-PPKRPITILDLMTHTSGITYGFY 174 K L DP++++ P V V +D L+ P +R I I DL+THTSG+ YGF Sbjct: 77 KLALRDPITRWAPELCKVAV-----LDDAAGPLDRTHPARRAILIEDLLTHTSGLAYGFS 131 Query: 175 GDSLVRKTYKEANI-YGGDFDLAEFAERIAKLPLHNQPGALWQYGHSTDILARVMEVTTG 233 + + Y+ G D LA +A LPL +QPG Y H+ D+L ++ Sbjct: 132 VSGPISRAYQRLPFGQGPDVWLAA----LATLPLVHQPGDRVTYSHAIDVLGVIVSRIED 187 Query: 234 EKLSTIERERLLDPLGMKDTGFFVTDPEKQKLMAEPMPNDSDFRVGRVNDPTKVK--KWE 291 L I ER+L P GM DTGF+V+ +++ ++ D V P V + Sbjct: 188 APLYQIIDERVLGPAGMTDTGFYVSADAQRRAATMYRLDEQDRLRHDVMGPPHVTPPSFC 247 Query: 292 SASGGMVSTMADYSRFAQML 311 +A GG+ ST DY RF +ML Sbjct: 248 NAGGGLWSTADDYLRFVRML 267