BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0034.0100.p         (265 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SMc00495 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxam...   451   e-127
mll0069 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxami...   445   e-125
BMEI1122 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxam...   444   e-124
AGc3382 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxami...   441   e-124
CC2491 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamid...   385   e-107

>SMc00495 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase Sme Sinorhizobium meliloti
          Length = 254

 Score =  451 bits (1161), Expect = e-127,   Method: Compositional matrix adjust.
 Identities = 211/254 (83%), Positives = 240/254 (94%)

Query: 11  MSRRRRIYEGKAKVLYEGPEPGTLIQHFKDDATAFNAKKHQVIEGKGVLNNRISEYLFQH 70
           M+RRRRIYEGKAK+LYEGPEPGTLIQ FKDDATAFN KKH VI+GKGVLNNRISEY+F H
Sbjct: 1   MNRRRRIYEGKAKILYEGPEPGTLIQFFKDDATAFNKKKHDVIDGKGVLNNRISEYIFTH 60

Query: 71  LNDIGVPTHFIRRLNMREQLIREVEIVPLEVVVRNVAAGSLSQRLGIEEGTQLPRSIIEF 130
           LN IG+PTHFIRRLNMREQLI+EVEI+PLE+VVRNVAAGSL++RLGIEEGT LPRSIIEF
Sbjct: 61  LNKIGIPTHFIRRLNMREQLIKEVEIIPLEIVVRNVAAGSLAKRLGIEEGTVLPRSIIEF 120

Query: 131 YYKNDQLNDPMVSEEHITAFGWATPQEIDDIMALAIRVNDFLTGLFLGIGIRLVDFKMEC 190
           YYK D L+DPMVSEEHITAFGWA+PQE+DDIMALAIR+NDFL+GLFLG+GI+LVDFK+EC
Sbjct: 121 YYKADALDDPMVSEEHITAFGWASPQELDDIMALAIRINDFLSGLFLGVGIQLVDFKVEC 180

Query: 191 GRLFENEMMRIIVADEISPDSCRLWDIKSNEKLDKDRFRRDLGGLLEAYTEVAKRLGILI 250
           GRL+E +MMRI++ADEISPDSCRLWDI++ EK+DKDRFRRD+GGL+EAY EVA+RLGI+ 
Sbjct: 181 GRLYEGDMMRIVLADEISPDSCRLWDIETKEKMDKDRFRRDMGGLVEAYQEVARRLGIIN 240

Query: 251 ENERPAGSGPVLVK 264
           ENE P GSGPVLVK
Sbjct: 241 ENEPPRGSGPVLVK 254


>mll0069 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase Mlo Mesorhizobium loti
          Length = 264

 Score =  445 bits (1144), Expect = e-125,   Method: Compositional matrix adjust.
 Identities = 208/255 (81%), Positives = 237/255 (92%)

Query: 11  MSRRRRIYEGKAKVLYEGPEPGTLIQHFKDDATAFNAKKHQVIEGKGVLNNRISEYLFQH 70
           M  RRRIYEGKAK+LYEGPEPGTLIQ FKDDATAFN KKH+V++GKGVLNNRISE++F H
Sbjct: 1   MKNRRRIYEGKAKILYEGPEPGTLIQFFKDDATAFNKKKHEVVDGKGVLNNRISEHIFNH 60

Query: 71  LNDIGVPTHFIRRLNMREQLIREVEIVPLEVVVRNVAAGSLSQRLGIEEGTQLPRSIIEF 130
           LN +G+PTHFIRRLNMREQLI+EVEI+PLEVVVRNVAAGSLS+RLGIEEGT LPRSIIEF
Sbjct: 61  LNRMGIPTHFIRRLNMREQLIKEVEIIPLEVVVRNVAAGSLSKRLGIEEGTVLPRSIIEF 120

Query: 131 YYKNDQLNDPMVSEEHITAFGWATPQEIDDIMALAIRVNDFLTGLFLGIGIRLVDFKMEC 190
           YYK D L+DPMVSEEHITAFGWA+PQEIDD+MALAIRVNDFL+GLF+G+GI+LVDFK+EC
Sbjct: 121 YYKADALDDPMVSEEHITAFGWASPQEIDDVMALAIRVNDFLSGLFMGVGIQLVDFKIEC 180

Query: 191 GRLFENEMMRIIVADEISPDSCRLWDIKSNEKLDKDRFRRDLGGLLEAYTEVAKRLGILI 250
           GRLFE +MMRI+VADEISPDSCRLWD+ + +KLDKDRFRRD+GGL+EAY EVA+RLGI+ 
Sbjct: 181 GRLFEGDMMRIVVADEISPDSCRLWDVATQDKLDKDRFRRDMGGLVEAYQEVARRLGIMN 240

Query: 251 ENERPAGSGPVLVKS 265
           ENE P  +GPVLV S
Sbjct: 241 ENEPPRPTGPVLVAS 255


>BMEI1122 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase Bme Brucella melitensis
          Length = 254

 Score =  444 bits (1141), Expect = e-124,   Method: Compositional matrix adjust.
 Identities = 210/254 (82%), Positives = 237/254 (93%)

Query: 11  MSRRRRIYEGKAKVLYEGPEPGTLIQHFKDDATAFNAKKHQVIEGKGVLNNRISEYLFQH 70
           M+RRRRIYEGKAK+LYEGPEPGTL+Q FKDDATAFNAKKH+VI+GKGVLNNRISE++F  
Sbjct: 1   MNRRRRIYEGKAKILYEGPEPGTLVQFFKDDATAFNAKKHEVIDGKGVLNNRISEHIFTQ 60

Query: 71  LNDIGVPTHFIRRLNMREQLIREVEIVPLEVVVRNVAAGSLSQRLGIEEGTQLPRSIIEF 130
           LN IG+PTHFIRRLNMREQLI+EVEI+PLEVVVRNVAAGSL++ LG+EEGT LPRSIIEF
Sbjct: 61  LNRIGIPTHFIRRLNMREQLIKEVEIIPLEVVVRNVAAGSLAKHLGLEEGTILPRSIIEF 120

Query: 131 YYKNDQLNDPMVSEEHITAFGWATPQEIDDIMALAIRVNDFLTGLFLGIGIRLVDFKMEC 190
           YYK D L+DPMV+EEHITAFGWA+PQEIDDIMALAIRVNDFLTGLFLGIGI+LVDFKMEC
Sbjct: 121 YYKADALDDPMVTEEHITAFGWASPQEIDDIMALAIRVNDFLTGLFLGIGIQLVDFKMEC 180

Query: 191 GRLFENEMMRIIVADEISPDSCRLWDIKSNEKLDKDRFRRDLGGLLEAYTEVAKRLGILI 250
           GRL+E +MMRI+VADEISPDS RLWDI +N+KLDKDRFRRD+GGL+EAY EVA+RLGI+ 
Sbjct: 181 GRLWEGDMMRIVVADEISPDSARLWDITTNDKLDKDRFRRDMGGLVEAYQEVARRLGIMN 240

Query: 251 ENERPAGSGPVLVK 264
           EN+ P  SGP LVK
Sbjct: 241 ENDTPRPSGPTLVK 254


>AGc3382 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase Atu Agrobacterium tumefaciens strain C58
           (Cereon)
          Length = 254

 Score =  441 bits (1134), Expect = e-124,   Method: Compositional matrix adjust.
 Identities = 208/254 (81%), Positives = 237/254 (93%)

Query: 11  MSRRRRIYEGKAKVLYEGPEPGTLIQHFKDDATAFNAKKHQVIEGKGVLNNRISEYLFQH 70
           M+RRRRIYEGKAK+LYEGPEPGTLIQ FKDDATAFN KKH+VI+GKGVLNNRI EY+F H
Sbjct: 1   MNRRRRIYEGKAKILYEGPEPGTLIQFFKDDATAFNKKKHEVIDGKGVLNNRICEYVFTH 60

Query: 71  LNDIGVPTHFIRRLNMREQLIREVEIVPLEVVVRNVAAGSLSQRLGIEEGTQLPRSIIEF 130
           LN IG+PTHFIRRLNMREQLI+EVE++PLE+VVRNVAAGSLS+RLGIEEG  LPRSIIEF
Sbjct: 61  LNKIGIPTHFIRRLNMREQLIKEVEMIPLEIVVRNVAAGSLSKRLGIEEGVVLPRSIIEF 120

Query: 131 YYKNDQLNDPMVSEEHITAFGWATPQEIDDIMALAIRVNDFLTGLFLGIGIRLVDFKMEC 190
           YYK+D+L DPMVSEEHITAFGWA P E+DDIMALAIRVNDFL+GLFLG+GI+LVDFK+EC
Sbjct: 121 YYKSDELEDPMVSEEHITAFGWANPAELDDIMALAIRVNDFLSGLFLGVGIQLVDFKIEC 180

Query: 191 GRLFENEMMRIIVADEISPDSCRLWDIKSNEKLDKDRFRRDLGGLLEAYTEVAKRLGILI 250
           GRLFE +MMRII+ADEISPDSCRLWDI++ +K+DKD FRRDLGGL+EAY+EVA+RLGI+ 
Sbjct: 181 GRLFEGDMMRIILADEISPDSCRLWDIETQKKMDKDLFRRDLGGLVEAYSEVARRLGIIN 240

Query: 251 ENERPAGSGPVLVK 264
           ENE   G+GPVLVK
Sbjct: 241 ENEPIRGTGPVLVK 254


>CC2491 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase Ccr Caulobacter vibrioides
          Length = 252

 Score =  385 bits (989), Expect = e-107,   Method: Compositional matrix adjust.
 Identities = 177/240 (73%), Positives = 214/240 (89%)

Query: 12  SRRRRIYEGKAKVLYEGPEPGTLIQHFKDDATAFNAKKHQVIEGKGVLNNRISEYLFQHL 71
           +RR++IYEGKAK+LYEGPEPGTLIQ+FKDDATAFNA+K  ++EGKGV+NNRISEY+   L
Sbjct: 3   TRRKKIYEGKAKILYEGPEPGTLIQYFKDDATAFNAQKKAILEGKGVINNRISEYIMTRL 62

Query: 72  NDIGVPTHFIRRLNMREQLIREVEIVPLEVVVRNVAAGSLSQRLGIEEGTQLPRSIIEFY 131
           N IGV  HFIRRLN+REQLI+EVEIVPLEVVVRN+AAGS++ RLG+ EG  LPRSIIEFY
Sbjct: 63  NGIGVQNHFIRRLNLREQLIKEVEIVPLEVVVRNIAAGSIATRLGLTEGQPLPRSIIEFY 122

Query: 132 YKNDQLNDPMVSEEHITAFGWATPQEIDDIMALAIRVNDFLTGLFLGIGIRLVDFKMECG 191
           YK+D+L DPMV+EEHITAF WA  QEIDD+MA+A+RVND+L+GLF G+GI LVDFK+E G
Sbjct: 123 YKDDKLGDPMVTEEHITAFNWAATQEIDDMMAMALRVNDYLSGLFAGVGITLVDFKVEFG 182

Query: 192 RLFENEMMRIIVADEISPDSCRLWDIKSNEKLDKDRFRRDLGGLLEAYTEVAKRLGILIE 251
           R++E +  R+I+ADEISPDSCRLWD  +NEKLDKDRFRRDLG ++E+YTEVA+RLGI+ E
Sbjct: 183 RVYEGDFSRVILADEISPDSCRLWDTVTNEKLDKDRFRRDLGNVIESYTEVARRLGIMKE 242