BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0026.p (451 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3467 [GEPR] COG0477 Permeases of the major facilitator superfa... 269 1e-71 Cgl2919 [GEPR] COG0477 Permeases of the major facilitator superf... 259 6e-69 RSp0052 [GEPR] COG0477 Permeases of the major facilitator superf... 257 3e-68 BS_yceI [GEPR] COG0477 Permeases of the major facilitator superf... 234 3e-61 AGpA571 [GEPR] COG0477 Permeases of the major facilitator superf... 207 6e-53 >PA3467 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 455 Score = 269 bits (687), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 161/449 (35%), Positives = 249/449 (55%), Gaps = 9/449 (2%) Query: 5 SARIERLPFARFHVHLLLMGGLGYLFDAMDAAVLAFILPVLRTAWGLTNVETGVLGSSTF 64 + R+ERLP + +H + ++ L + FD+MD A++ F+L ++ +GL + + G+L SS+F Sbjct: 9 AERLERLPLSPYHRLVFVIIALAFFFDSMDLAMMTFLLGSIKAEFGLDSAQAGLLASSSF 68 Query: 65 VGYLFGALLAGTLGDLIGRRAVMMSALALYSAASLVSAAVDSWPAFFAARVVAGMGTGAE 124 G + GA L+G L D GR+ V +++ L+ AS + + + RV+ G+G G E Sbjct: 69 FGMVIGAALSGMLADRFGRKPVFQASIVLWGLASYLCSTAGDLDSLTFYRVLLGIGMGME 128 Query: 125 SAIIAPYLAEFVARRYRGAFTGALAGFFSFGFVAAALLGYFIVPAYENGWRIVLVITAVP 184 I L+E + RG + + GF+ GFVAA L YF++P GWR + ++ A+P Sbjct: 129 FPIAQSLLSEMIPASRRGKYIALMDGFWPLGFVAAGCLSYFLLPL--TGWRSIFLVLALP 186 Query: 185 VVMLLWWRRSLPESPRWLESRGRAKEAEAVLDRIEASFARE--GRALPAPIAEPAAPVAS 242 V +L R +PESPRWLE GR ++A+ VL IEA R LP P+ +P + Sbjct: 187 AVFVLAIRFLIPESPRWLEQAGRREQADRVLRDIEARVMRSLGLTELPPPLRQPQRERSR 246 Query: 243 SGTLLSNFAALLAGRQARITTMTWIMWLSITFSYYSFFVWIPGLLVQNGMSITKSFGYSL 302 G S FA L + R T W +W +Y W+ LL Q+G ++T+S Y++ Sbjct: 247 PG-FFSAFAELWSPAYRRRTLTVWGLWFFALLGFYGLTSWLSALLQQSGFAVTQSVYYTV 305 Query: 303 AMYCAQVPGYFTAAFFNERIGRQATIATYMLLGGASALGLA----FAKSDAEIMTAGLLL 358 + A +PG+ AA+ E GR+ + +L GGA A F S A ++ GL + Sbjct: 306 LISLAGIPGFLCAAWLVESWGRKPSCVLMLLGGGAMAYAYGQTAVFGGSLALLIGFGLAM 365 Query: 359 SFFMNGTYAGVYAYTAEVFPTSIRTTGAGLASAIGRIGAIAAPILVGYLYPNFGFAGVFG 418 FF+ G +A +Y YT E++PTS R TG+G ASA+GRIG++ P++ G + P G GVF Sbjct: 366 QFFLFGMWAVLYTYTPELYPTSARATGSGFASAVGRIGSLLGPLVTGLVLPLTGQGGVFT 425 Query: 419 VTTSVLLIGALTVVLMGVPTRGRSLEDIA 447 + + AL V G+ TRGR+LE++A Sbjct: 426 LGALCFGVAALVVWAFGIETRGRTLEELA 454 >Cgl2919 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 439 Score = 259 bits (663), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 157/403 (38%), Positives = 231/403 (57%), Gaps = 12/403 (2%) Query: 5 SARIERLPFARFHVHLLLMGGLGYLFDAMDAAVLAFILPVLRTAWGLTNVETGVLGSSTF 64 + R++RLP H +L G+G+ DAMD +++F++ L T WGL+ ET +LGS F Sbjct: 6 NDRLDRLPVTSKHKKILGGSGIGWALDAMDVGLISFVMAALATHWGLSPTETSLLGSIGF 65 Query: 65 VGYLFGALLAGTLGDLIGRRAVMMSALALYSAASLVSAAVDSWPAFFAARVVAGMGTGAE 124 VG GA L G L D +GRR V +L +Y A+ SA S A R V G+G GAE Sbjct: 66 VGMAIGASLGGLLADKLGRRQVFALSLLVYGVATGASALSVSLAMLMALRFVVGLGLGAE 125 Query: 125 SAIIAPYLAEFVARRYRGAFTGALAGFFSFGFVAAALLGYFIVPAYENGWRIVLVITAVP 184 + + ++EF R+ RG L F++ G++ AA++G F+V +NGWR L + VP Sbjct: 126 LPVASTLISEFSPRKVRGRMVVILEAFWALGWIMAAIVGTFVVAGSDNGWRWALALGCVP 185 Query: 185 VVMLLWWRRSLPESPRWLESRGRAKEAEAVLDRIEASFAREGRALPAPIAEPAAPV---A 241 + ++ R LPES R+LE +GR EAEA++ SF A A V A Sbjct: 186 AIYAVYVRLGLPESVRFLEKKGRHDEAEAIV----VSFEEAAAAEGKAADATTAVVHDNA 241 Query: 242 SSGTLLSNFAALLAGRQARITTMTWIMWLSITFSYYSFFVWIPGLLVQNGMSITKSFGYS 301 + G+ +S ++A L R T WI+W I SYY F+WIP LLV +G ++ KSF ++ Sbjct: 242 AEGS-VSIWSAALRKR----TVALWIVWFCINLSYYGAFIWIPSLLVADGFTLVKSFQFT 296 Query: 302 LAMYCAQVPGYFTAAFFNERIGRQATIATYMLLGGASALGLAFAKSDAEIMTAGLLLSFF 361 L + AQ+PGY AA+ E+ GR++T+AT+++ SA A + +I+ AG LLSFF Sbjct: 297 LIITLAQLPGYAVAAWLIEKWGRRSTLATFLVGSAISAALYGLANVEWQILVAGCLLSFF 356 Query: 362 MNGTYAGVYAYTAEVFPTSIRTTGAGLASAIGRIGAIAAPILV 404 G + +YA E++PT++R TG G A+ GRI +I AP++V Sbjct: 357 NLGAWGALYAIGPELYPTNVRGTGTGAAAGFGRIASIIAPLIV 399 >RSp0052 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 476 Score = 257 bits (657), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 163/451 (36%), Positives = 248/451 (54%), Gaps = 11/451 (2%) Query: 7 RIERLPFARFHVHLLLMGGLGYLFDAMDAAVLAFILPVLRTAWGLTNVETGVLGSSTFVG 66 R+ERLPF+ +H + ++ + + FD++D A + F+L ++ +GL+ G++ SS+F G Sbjct: 16 RLERLPFSGYHKRIFIIIAIAFFFDSVDLATMTFVLGSIKKEFGLSTATAGLVASSSFFG 75 Query: 67 YLFGALLAGTLGDLIGRRAVMMSALALYSAASLVSAAVDSWPAFFAARVVAGMGTGAESA 126 + GA +AG L D GRR V ++ L+ AS + + S A A R++ G+G G E Sbjct: 76 MVIGAAVAGLLADRFGRRPVFQWSMVLWGVASYLCSTAQSVEALIAWRILLGIGMGMEFP 135 Query: 127 IIAPYLAEFVARRYRGAFTGALAGFFSFGFVAAALLGYFIVPAYENGWRIVLVITAVPVV 186 + L+EFV RG + GF+ GF+ A ++ YF++P + GWR V + AVP + Sbjct: 136 VAQTLLSEFVPTANRGRLIALMDGFWPLGFITAGIVSYFVLPQF--GWRAVFALLAVPAI 193 Query: 187 MLLWWRRSLPESPRWLESRGRAKEAEAVLDRIEASFAR--EGRALPAPIAEPAAPVASSG 244 +L RR++PESPRWLE GR +A+ V+ IEA R LP PI + +AP Sbjct: 194 FVLIVRRAVPESPRWLEHAGRNAQADTVMRGIEAKVMRSLNTTTLP-PIVQHSAPQPVRR 252 Query: 245 TLLSNFAALLAGRQARITTMTWIMWLSITFSYYSFFVWIPGLLVQNGMSITKSFGYSLAM 304 S + + R TTM W++W +Y W+ LL Q G ++T+S Y++ + Sbjct: 253 H--SALREIWSAAYRRRTTMVWLLWFFALLGFYGLTSWLGALLQQAGFAVTQSVYYTVLI 310 Query: 305 YCAQVPGYFTAAFFNERIGRQATIATYMLLGGASAL----GLAFAKSDAEIMTAGLLLSF 360 VPG+ AA+ ER GR+ T +L GGA A + S ++ GL + F Sbjct: 311 SLGGVPGFLCAAWLVERWGRKPTCIASLLGGGAMAYLYGQSALYGGSVTLLICTGLAMQF 370 Query: 361 FMNGTYAGVYAYTAEVFPTSIRTTGAGLASAIGRIGAIAAPILVGYLYPNFGFAGVFGVT 420 F+ G +A +Y YT E + T R TG+G ASAIGR+G++ P +VG + P FG GVF + Sbjct: 371 FLFGMWAVLYTYTPEQYGTGARATGSGFASAIGRVGSLIGPYVVGVVLPVFGQGGVFTLG 430 Query: 421 TSVLLIGALTVVLMGVPTRGRSLEDIASEAA 451 + AL V +G+ TRG +LE +ASE A Sbjct: 431 AISFAVAALAVWALGIETRGLALEALASEDA 461 >BS_yceI [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 400 Score = 234 bits (598), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 153/427 (35%), Positives = 229/427 (53%), Gaps = 38/427 (8%) Query: 19 HLLLMGGLGYLFDAMDAAVLAFILPVLRTAWGLTNVETGVLGSSTFVGYLFGALLAGTLG 78 LL + GLG+LFDAMD +L+FI+ L W L+ E +GS +G GA L G L Sbjct: 11 KLLGVAGLGWLFDAMDVGILSFIIAALHVEWNLSPEEMKWIGSVNSIGMAAGAFLFGLLA 70 Query: 79 DLIGRRAVMMSALALYSAASLVSAAVDSWPAFFAARVVAGMGTGAESAIIAPYLAEFVAR 138 D IGR+ V + L +S S +SA V S AF R V GMG G E + + ++E V Sbjct: 71 DRIGRKKVFIITLLCFSIGSGISAFVTSLSAFLILRFVIGMGLGGELPVASTLVSEAVVP 130 Query: 139 RYRGAFTGALAGFFSFGFVAAALLGYFIVPAYENGWRIVLVITAVPVVMLLWWRRSLPES 198 RG L F++ G++AAAL+ YF++P++ GW+ L++TA+ L+ R SLP+S Sbjct: 131 EKRGRVIVLLESFWAVGWLAAALISYFVIPSF--GWQAALLLTALTAFYALYLRTSLPDS 188 Query: 199 PRWLESRGRAKEAEAVLDRIEASFAREGRALPAPIAEPAAPVASSGTLLSNFAALLAGRQ 258 P++ ES K ++ N ++ A + Sbjct: 189 PKY-ESLSAKKR----------------------------------SMWENVKSVWARQY 213 Query: 259 ARITTMTWIMWLSITFSYYSFFVWIPGLLVQNGMSITKSFGYSLAMYCAQVPGYFTAAFF 318 R T M I+W + FSYY F+W+P +++ G S+ +SF Y L M AQ+PGYF+AA+ Sbjct: 214 IRPTVMLSIVWFCVVFSYYGMFLWLPSVMLLKGFSMIQSFEYVLLMTLAQLPGYFSAAWL 273 Query: 319 NERIGRQATIATYMLLGGASALGLAFAKSDAEIMTAGLLLSFFMNGTYAGVYAYTAEVFP 378 E+ GR+ + Y++ SA A S + ++TAG+LLSFF G + +YAYT E +P Sbjct: 274 IEKAGRKWILVVYLIGTAGSAYFFGTADSLSLLLTAGVLLSFFNLGAWGVLYAYTPEQYP 333 Query: 379 TSIRTTGAGLASAIGRIGAIAAPILVGYLYP-NFGFAGVFGVTTSVLLIGALTVVLMGVP 437 T+IR TG+G +A GRIG I P+LVG L + F+ +F + +L+ +++MG Sbjct: 334 TAIRATGSGTTAAFGRIGGIFGPLLVGTLAARHISFSVIFSIFCIAILLAVACILIMGKE 393 Query: 438 TRGRSLE 444 T+ LE Sbjct: 394 TKQTELE 400 >AGpA571 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 461 Score = 207 bits (526), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 152/453 (33%), Positives = 228/453 (50%), Gaps = 22/453 (4%) Query: 4 ISARIERLPFARFHVHLLLMGGLGYLFDAMDAAVLAFILPVLRTAWGLTNVETGVLGSST 63 ISAR+ERLP R + G FD +A+ +PVL WGLT +TG++ S Sbjct: 21 ISARLERLPITREVFWARNIVGAATFFDGYTVIAIAYAMPVLVREWGLTPSQTGMILSMG 80 Query: 64 FVGYLFGALLAGTLGDLIGRRAVMMSALALY---SAASLVSAAVDSWPAFFAARVVAGMG 120 ++G L GA+L G L + IGR V++ + L+ A L +A AF R V G+G Sbjct: 81 YLGQLIGAILFGWLAERIGRLKVLLFTILLFVSMDVACLFAAGAGMMMAF---RFVQGIG 137 Query: 121 TGAESAIIAPYLAEFVARRYRGAFTGALAGFFSFGFVAAALLGYFIVPAYENGWRIVLVI 180 TG E + + Y+ E + + RG F F G V A L+GYF+VP Y GW+ + ++ Sbjct: 138 TGGEVPVASAYINELIGSKGRGRFFLLYEVMFLLGLVGAGLIGYFMVPLY--GWKAMFIV 195 Query: 181 TAVPVVMLLWWRRSLPESPRWLESRGRAKEAEAVLDRIEASFAREGRALPAP--IAEPAA 238 VP ++++ R L ESPRWL + GR EA ++ R+E S G+ALP P IA PA Sbjct: 196 GLVPAMLMIPLRWFLKESPRWLAATGRYDEANVIVKRMEESARAAGKALPEPRIIATPAK 255 Query: 239 PVASSGTLLSNFAALLAGRQARITTMTWIMWLSITFSYYSFFVWIPGLLVQN-GMSITKS 297 V S++ L G + T W MW W+P L Q + + S Sbjct: 256 RV-------SDWRELFQGIYLKRTLSIWAMWFCAYMVANGTITWLPTLYRQTFNLPLETS 308 Query: 298 FGYSLAMYCAQVPGYFTAAFFNERIGRQATIATYMLLGGASALGLAF--AKSDAEIMT-A 354 Y A V A +++GR+ A +LL LA+ A S +++ A Sbjct: 309 ILYGFMTSAAGVVAAVICALLIDKVGRKRWYAGALLLAPVPLAILAWLGATSPMQVLIFA 368 Query: 355 GLLLSFFMNGTYAGVYAYTAEVFPTSIRTTGAGLASAIGRIGAIAAPILVGYLYPNFGFA 414 GL + T++ +Y Y+AE++PT +R G G SA R+G+ A P+LVG++ + G Sbjct: 369 GLAYAIVQTVTFS-LYLYSAEIYPTRMRAIGTGAGSAWLRLGSSAGPMLVGFVMSSMGIQ 427 Query: 415 GVFGVTTSVLLIGALTVVLMGVPTRGRSLEDIA 447 VF +L+IGA+ +L V T+G+ LE+++ Sbjct: 428 YVFATFAFILIIGAVVTMLFAVETKGKVLEELS 460