BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0081.p (341 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll3393 [E] COG0006 Xaa-Pro aminopeptidase Mlo Mesorhizobium loti 328 9e-90 SMa1329 [E] COG0006 Xaa-Pro aminopeptidase Sme Sinorhizobium mel... 318 1e-86 BS_yqhT [E] COG0006 Xaa-Pro aminopeptidase Bsu Bacillus subtilis 74 3e-13 PAE2025 [E] COG0006 Xaa-Pro aminopeptidase Pya Pyrobaculum aerop... 68 3e-11 L96847 [E] COG0006 Xaa-Pro aminopeptidase Lla Lactococcus lactis 68 4e-11 >mll3393 [E] COG0006 Xaa-Pro aminopeptidase Mlo Mesorhizobium loti Length = 395 Score = 328 bits (842), Expect = 9e-90, Method: Compositional matrix adjust. Identities = 155/285 (54%), Positives = 205/285 (71%) Query: 13 PFDTAKLDRLMDEAGLDILIVTSRHNVQYLLGGYRFFFFDVMEAIGTSRYLPVFVYQKGH 72 PFD A++DRLM+EAG+D+L+ TS+HN QYLLGGY+F FF M+AIG SRYLP+ VY+KG Sbjct: 14 PFDQARVDRLMEEAGIDVLLATSKHNTQYLLGGYKFIFFAAMDAIGHSRYLPIVVYEKGG 73 Query: 73 PENSAYIGNRMEKFEQQLGRIWTPIVKAEVWGTIDAIGLAIDHVRKLAGSARRIGIEAGF 132 PE++AYIGNRME E Q WTP + A WGT+DA LA++H++K ++ RIGIE GF Sbjct: 74 PEHAAYIGNRMEGGEHQNNPFWTPTLHAACWGTLDAANLAVEHLQKFGRASARIGIEPGF 133 Query: 133 LPAAARDHLHAGLGDVEFREAHFTLERLRAVKSPAELDLIREASERVVDAMMATFKGCAP 192 LP+ A + L D + +A LER+RA+K+ AEL+ +R ASE + D+M+AT Sbjct: 134 LPSDAYTLIRKALPDAKLIDATDMLERMRAIKTNAELEKLRTASELITDSMLATIAWARE 193 Query: 193 GMTKNDVVARLRREEHERDLVFEYCLIAAGKSHNRAPSNQLLAERDVISIDSGGNYRGYI 252 G TK +++ +LRREE R FEYCL+ G SHNRA S Q + +V+SIDSGGNY GYI Sbjct: 194 GTTKAEMIEQLRREETNRGAHFEYCLLTLGSSHNRAASPQAWKKGEVLSIDSGGNYHGYI 253 Query: 253 GDLSRMGILGEPDSELSELLQEIEDIQQVARRAIRPGVMGGDIIA 297 GDL RMGILGEPD+EL +LL E+E +QQ A ++ G +GGD+I+ Sbjct: 254 GDLCRMGILGEPDAELEDLLAEVETVQQAAFSKVKAGTLGGDMIS 298 >SMa1329 [E] COG0006 Xaa-Pro aminopeptidase Sme Sinorhizobium meliloti Length = 397 Score = 318 bits (815), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 151/276 (54%), Positives = 198/276 (71%) Query: 23 MDEAGLDILIVTSRHNVQYLLGGYRFFFFDVMEAIGTSRYLPVFVYQKGHPENSAYIGNR 82 M+EAG+D+L+ TS+HN QYLLGGY+F FF M+AIG SRYLP+ VY+KG P++SAYIGNR Sbjct: 1 MEEAGIDVLLATSKHNTQYLLGGYKFIFFAAMDAIGHSRYLPIVVYEKGSPDHSAYIGNR 60 Query: 83 MEKFEQQLGRIWTPIVKAEVWGTIDAIGLAIDHVRKLAGSARRIGIEAGFLPAAARDHLH 142 ME E Q WTP V WGT+DA LA++H+RK+ + R+GIE FLPA ARD Sbjct: 61 MEGGEHQNNPFWTPAVHTATWGTLDAAALAVEHLRKIGKAGARVGIEPSFLPADARDLFA 120 Query: 143 AGLGDVEFREAHFTLERLRAVKSPAELDLIREASERVVDAMMATFKGCAPGMTKNDVVAR 202 + L F +A TLERLR++K+P EL+ ++ ASE + D+M+AT G TK +++ R Sbjct: 121 SRLDGARFVDATHTLERLRSIKTPQELEKLKVASELITDSMLATIAAAREGSTKGEIIER 180 Query: 203 LRREEHERDLVFEYCLIAAGKSHNRAPSNQLLAERDVISIDSGGNYRGYIGDLSRMGILG 262 LRREE R L FEYCL+ G SHNRA S Q A+ +V+SIDSGGNY+GYIGDL RMG+LG Sbjct: 181 LRREETNRGLHFEYCLLTLGASHNRAASPQAWAKGEVLSIDSGGNYQGYIGDLCRMGVLG 240 Query: 263 EPDSELSELLQEIEDIQQVARRAIRPGVMGGDIIAA 298 EPD+EL +LL E++ IQ+ A I+ G G ++IA+ Sbjct: 241 EPDAELEDLLAEVDSIQKAAFARIKAGATGSEMIAS 276 >BS_yqhT [E] COG0006 Xaa-Pro aminopeptidase Bsu Bacillus subtilis Length = 353 Score = 74.3 bits (181), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 71/297 (23%), Positives = 124/297 (41%), Gaps = 35/297 (11%) Query: 18 KLDRLMDEAGLDILIVTSRHNVQYLLGGYRFFFFDVMEAIGTSRYLPVFVYQKGHPENSA 77 KL L + G+D +++TS NV+Y+ G F + I + F+ + E + Sbjct: 5 KLRNLFGQLGIDGMLITSNTNVRYMTG---FTGSAGLAVISGDK--AAFITDFRYTEQAK 59 Query: 78 YIGNRMEKFEQQLGRIWTPIVKAEVWGTIDAIGLAIDHVRKLAGSARRIGIEAGFLPAAA 137 E E I T E +G +R+G E + Sbjct: 60 VQVKGFEIIEHGGSLIQTTADTVESFGI------------------KRLGFEQNSMTYGT 101 Query: 138 RDHLHAGLGDVEFREAHFTLERLRAVKSPAELDLIREASERVVDAMMATFKGCAPGMTKN 197 A + D E ++E+LR +KS E+ ++ EA++ DA PG+++ Sbjct: 102 YASYSAVISDAELVPVAESVEKLRLIKSSEEIKILEEAAKIADDAFRHILTFMKPGISEI 161 Query: 198 DVVARLR---REEHERDLVFEYCLIAAGKSH--NRAPSNQLLAERDVISIDSGGNYRGYI 252 V L R + F+ + + +S + S++L+ D++++D G Y+GY Sbjct: 162 AVANELEFYMRSQGADSSSFDMIVASGLRSSLPHGVASDKLIESGDLVTLDFGAYYKGYC 221 Query: 253 GDLSRMGILGEPDSELSELLQEIEDIQQVARRAIRPGVMGG-------DIIAAGGXG 302 D++R +G+P +L E+ Q + D Q + I+PG+ G D IAA G G Sbjct: 222 SDITRTVAVGQPSDQLKEIYQVVFDAQALGVAHIKPGMTGKEADALTRDHIAAKGYG 278 >PAE2025 [E] COG0006 Xaa-Pro aminopeptidase Pya Pyrobaculum aerophilum Length = 323 Score = 68.2 bits (165), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 52/193 (26%), Positives = 94/193 (48%), Gaps = 17/193 (8%) Query: 149 EFREAHFTLERLRAVKSPAELDLIREASE---RVVDAMMATFKGCAPGMTKNDVVARLRR 205 E R A ++RA+K E++ I+ A E RV++A+ APG+++ + + + Sbjct: 97 ELRLADDLFRQMRAIKREEEVEKIKRAVEEIRRVLEALE-----LAPGVSEREAAFFIYK 151 Query: 206 EEHERDLVFEYCLIAAGKSHN---RAPSNQLLAERDVISIDSGGNYRGYIGDLSRMGILG 262 +E L L+ G++ + + P+ + L + + +D +YRGY GDL++ G Sbjct: 152 ALYEAGLEPGPILVQFGQNTSLPHQEPTGKKLQRGEAVVLDVTASYRGYFGDLTKSFYYG 211 Query: 263 EPDSELSELLQEIEDIQQVARRAIRPGVMGGDIIAAGGXGGRRILSASCRAR--LHRTRH 320 EP + +E+ + +E+ Q A +A RPG + D+ A R ++ R +HRT H Sbjct: 212 EPPAHYAEVYRLVEEAQLSALKAARPGALASDVDKA----ARSVIETRGYGRYFIHRTGH 267 Query: 321 WACQPRSAAPDCN 333 APD + Sbjct: 268 GLGLELHEAPDIS 280 >L96847 [E] COG0006 Xaa-Pro aminopeptidase Lla Lactococcus lactis Length = 362 Score = 67.8 bits (164), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 49/191 (25%), Positives = 93/191 (48%), Gaps = 10/191 (5%) Query: 114 DHVRKLAGSARRIGIEAGFLPAAARDHLHAGLGDVEFREAHFTLERLRAVKSPAELDLIR 173 +HV+ + I +E +P A + L A GD+ F +ER+R +KS E++ ++ Sbjct: 88 NHVKS---DVKSIAVEFSDIPLAKTEGLKAQFGDINFVNLTPLIERMRLIKSADEIEKMK 144 Query: 174 EASERVVDAMMATFKGCAP--GMTKNDVVARLRREEHER---DLVFEYCLIAAGKSHNR- 227 A + F A G+T++D+VA++ E + F+ +++ ++ N Sbjct: 145 VAGDFADKCFEIGFATAAERNGVTESDIVAKIEYEMKRMGVPQMSFDTLVLSGARAANPH 204 Query: 228 -APSNQLLAERDVISIDSGGNYRGYIGDLSRMGILGEPDSELSELLQEIEDIQQVARRAI 286 AP N + E ++ D G GY D +R +G+P+ +E+ + +++ QQ A I Sbjct: 205 GAPENVEIQENKLLLFDLGVMSGGYASDATRTIAIGQPNDFDAEIHKIVKEAQQAAMDFI 264 Query: 287 RPGVMGGDIIA 297 +PGV ++ A Sbjct: 265 KPGVTAHEVDA 275