BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0068.p (538 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc00339_2 [T] COG2114 Adenylate cyclase, family 3 (some protein... 201 5e-51 SMb20776_2 [T] COG2114 Adenylate cyclase, family 3 (some protein... 170 1e-41 alr2266_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 147 8e-35 all1904_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 146 1e-34 all1118_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 132 1e-30 >SMc00339_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Sme Sinorhizobium meliloti Length = 360 Score = 201 bits (510), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 104/260 (40%), Positives = 151/260 (58%) Query: 213 LLARSLRELARQTDGIQRFQLADRPRMQSAIDEIDELGRSVFTMRTVVRNFSSFIPQPIV 272 L+ +SL +L + +Q A + S + EI L ++ R + F+ ++P+ +V Sbjct: 87 LITKSLNQLTDSANRLQDLDFATPIDVSSHVAEISTLNGAMNRARDAIFTFALYVPKELV 146 Query: 273 RQLMQSGASLQLGGIRREVTVLFTDVADFTAKTEKADPSQVMIFTSRYFAAMSEAIMKHH 332 R+ ++SG R+EVT +FTD+ DFT +E P +V+ S YF SE + H Sbjct: 147 RKGIESGHFGGRAAWRQEVTAMFTDIYDFTTISEGRSPEEVVAMLSEYFDLFSEVVAAHD 206 Query: 333 GTIDKFIGDAVMALWNAPDEDPDHVVHACEAVLDCIHRNAELNRAFRSEGWPAYGTRFGL 392 GTI +F GD+V A+WNAP D H HAC L R N A R+ G P + TRFG+ Sbjct: 207 GTIIQFHGDSVFAMWNAPVADTRHAEHACRCALAVEERLEAFNSAQRASGLPEFRTRFGI 266 Query: 393 HLGDAVVGNVGSAARMSYTALGATINLASRLEGLNKNYGTQVLVSAAVRARAEHRFAFRS 452 H G AVVG+VG+ R+ YTA+G T+N+ASRLEG+NK+YGT VL S AV A+ + FR Sbjct: 267 HTGTAVVGSVGAKERLQYTAMGDTVNVASRLEGMNKDYGTSVLASGAVVAQCKDMVKFRP 326 Query: 453 VDQIRPKGFADAITVYELCG 472 + + KG + A+ +YE+ G Sbjct: 327 LGTAKAKGRSTALDIYEVVG 346 >SMb20776_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Sme Sinorhizobium meliloti Length = 283 Score = 170 bits (430), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 92/220 (41%), Positives = 129/220 (58%), Gaps = 8/220 (3%) Query: 259 VVRNFSSFIPQPIVRQLMQSGASLQLGGIRREVTVLFTDVADFTAKTE--KADPSQVMIF 316 + R FS ++ +V +L + + L+LGG RR +TVLF DV FT +E K DP + Sbjct: 10 ITRAFSQYLSPALVERLARDPSQLKLGGERRTLTVLFCDVRGFTTISEDMKDDPEGLTTL 69 Query: 317 TSRYFAAMSEAIMKHHGTIDKFIGDAVMALWNAPDEDPDHVVHACEAVLDCI----HRNA 372 +R +SEA++ GTIDK+IGD +MA WNAP +DPDH VHA +A D + NA Sbjct: 70 INRLLTPLSEAVLNRRGTIDKYIGDCLMAFWNAPLDDPDHAVHAVQAARDMLTALGDLNA 129 Query: 373 ELNRAFRSEGWPAYGTR--FGLHLGDAVVGNVGSAARMSYTALGATINLASRLEGLNKNY 430 EL ++ G P R G++ G+ VVGN+GSA R Y+ALG +NLASRLEG +K+Y Sbjct: 130 ELQAEAKAAGRPPKALRIGIGINTGECVVGNMGSARRFDYSALGDAVNLASRLEGASKDY 189 Query: 431 GTQVLVSAAVRARAEHRFAFRSVDQIRPKGFADAITVYEL 470 G +L+ A +FA +D+I KG + V+ L Sbjct: 190 GVPLLLGERTATLAARKFAVAELDRITVKGRSAVSPVFTL 229 >alr2266_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 296 Score = 147 bits (370), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 90/273 (32%), Positives = 136/273 (49%), Gaps = 9/273 (3%) Query: 266 FIPQPIVRQLMQSGASLQLGGIRREVTVLFTDVADFTAKTEKADPSQVMIFTSRYFAAMS 325 ++ + Q+M G + G R+EVTVLF+D+ +T TE ++V+ ++YF M Sbjct: 12 YLTPHVAEQVMALGEDALMVGERKEVTVLFSDIRGYTTLTENLGAAEVVSLLNQYFETMV 71 Query: 326 EAIMKHHGTIDKFIGDAVMALWNAP-DEDPDHVVHACEAVLDCIHRNAELNRAFRSEGWP 384 EA+ + GT+DKFIGDA+MA++ AP +H A ++ LD R E N+ + P Sbjct: 72 EAVFNYEGTLDKFIGDALMAVFGAPLPLTENHAWQAVQSALDMRQRLKEFNQRRIIQAQP 131 Query: 385 AYGTRFGLHLGDAVVGNVGSAARMSYTALGATINLASRLEGLNKNYGTQVLVSAAVRARA 444 G+ G+ V GN+GS RM YT +G +NL+SRLE + K YG +++S Sbjct: 132 QIKIGIGISSGEVVSGNIGSHKRMDYTVIGDGVNLSSRLETVTKEYGCDIILSEFTYQLC 191 Query: 445 EHRFAFRSVDQIRPKGFADAITVYELCGERG----DSELTFCARWEAVYSS--IRYAEPA 498 R R +D+IR KG A+ +YEL +R D+ F + ++ +R A Sbjct: 192 SDRIWVRQLDKIRVKGKHQAVNIYELISDRSTPLDDNTQEFLFHYHNGRTAYLVRDFTQA 251 Query: 499 AAALRIADFLVEYPWDCVAQYHAERLRNAAQQP 531 A A + P D H ER N Q P Sbjct: 252 IACFNSAKHI--RPTDQAVNIHLERAYNYQQTP 282 >all1904_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 296 Score = 146 bits (369), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 72/211 (34%), Positives = 123/211 (58%), Gaps = 1/211 (0%) Query: 266 FIPQPIVRQLMQSGASLQLGGIRREVTVLFTDVADFTAKTEKADPSQVMIFTSRYFAAMS 325 ++ Q + +L++ + +LGG R+EV++LF+D+ +T TE + +V+ + YF +M Sbjct: 12 YMTQELAEELLKLDDA-KLGGDRKEVSILFSDIRGYTTLTENLEAEEVVSMLNEYFESMV 70 Query: 326 EAIMKHHGTIDKFIGDAVMALWNAPDEDPDHVVHACEAVLDCIHRNAELNRAFRSEGWPA 385 EA+ KH GT+DK+IGDA+MA++ +P +H A + ++ HR E N+ + P Sbjct: 71 EAVFKHKGTLDKYIGDAIMAVFGSPLPLEEHAWMAVKTSIEMRHRLQEFNQKRYAANKPR 130 Query: 386 YGTRFGLHLGDAVVGNVGSAARMSYTALGATINLASRLEGLNKNYGTQVLVSAAVRARAE 445 G++ + GN+GS+ RM +TA+G +NL SRLE ++K YG +++S + Sbjct: 131 INIGIGINSDTVISGNIGSSKRMEFTAIGDGVNLGSRLESVSKQYGCDIILSDNTFKPCQ 190 Query: 446 HRFAFRSVDQIRPKGFADAITVYELCGERGD 476 R +D IR KG + +++YEL G R D Sbjct: 191 ENIWARELDFIRVKGRNEPVSIYELIGLRSD 221 >all1118_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 322 Score = 132 bits (333), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 68/216 (31%), Positives = 114/216 (52%), Gaps = 2/216 (0%) Query: 266 FIPQPIVRQLMQSGASLQLGGIRREVTVLFTDVADFTAKTEKADPSQVMIFTSRYFAAMS 325 ++ ++ ++++ + L+LGG RR+VT+LF+D+ F+A +E+ P QV+ + Y M+ Sbjct: 4 YLTDEVLANILETPSGLKLGGERRKVTLLFSDLRGFSAMSEQLSPEQVVQILNLYLGVMT 63 Query: 326 EAIMKHHGTIDKFIGDAVMALWNAPDEDPDHVVHACEAVLDCIHRNAELNRAFRSEGWPA 385 + I ++ GTI++FIGD + ++ AP PD A + ++N P Sbjct: 64 DVINQYKGTINEFIGDGIFIMFGAPICRPDDSQRAIACAIAMQRAMQQVNAKTHQMNLPQ 123 Query: 386 YGTRFGLHLGDAVVGNVGSAARMSYTALGATINLASRLEGLNKNYGTQVLVSAAVRARAE 445 G++ G+ V GN+GS R YT +G+ +NLA+R+E G Q+L+S R A Sbjct: 124 LEMGIGINTGEVVAGNIGSQKRAQYTVIGSHVNLAARIE--TYTVGGQILISENTRQDAN 181 Query: 446 HRFAFRSVDQIRPKGFADAITVYELCGERGDSELTF 481 QI PKG + IT+YE+ G G L+ Sbjct: 182 TDLQIAGQMQIEPKGIKEPITIYEISGIGGAYNLSL 217