BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0056.p (555 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll5471 [P] COG3119 Arylsulfatase A and related enzymes Mlo Meso... 582 e-165 SMb20915 [P] COG3119 Arylsulfatase A and related enzymes Sme Sin... 566 e-161 SMa0943 [P] COG3119 Arylsulfatase A and related enzymes Sme Sino... 560 e-159 MA2648 [P] COG3119 Arylsulfatase A and related enzymes Mac Metha... 541 e-153 SMb20332 [P] COG3119 Arylsulfatase A and related enzymes Sme Sin... 226 9e-59 >mll5471 [P] COG3119 Arylsulfatase A and related enzymes Mlo Mesorhizobium loti Length = 557 Score = 582 bits (1499), Expect = e-165, Method: Compositional matrix adjust. Identities = 313/552 (56%), Positives = 374/552 (67%), Gaps = 28/552 (5%) Query: 1 MKSETKKHDAGANSDCGASTIDRRAVLLGTSSLAATAALTSQALAQAQKAAPAAAPAGGR 60 M + K +AG N S + RR VLLG ++LAA +AL + +AA A G Sbjct: 1 MGTGNNKVEAG-NQITQGSLVSRRNVLLGGTTLAAASALAGSNPIRLAQAA-----AAGS 54 Query: 61 KPNILVIFGDDIGIPQISAYTMGMMGYRTPNIDRIAREGAIFTDAYGQQSCTAGRASFIL 120 KPNILVIFGDDIG SAY GMMGYRTPNIDRIAREGAIFTD Y QQSCTAGRA+FI Sbjct: 55 KPNILVIFGDDIGYWNTSAYNRGMMGYRTPNIDRIAREGAIFTDLYAQQSCTAGRAAFIT 114 Query: 121 GQEPFRTGLLTIGMPGDPHGIQDWMPTIADAMKTQGYATGQFGKNHLGDRDEHLPTKHGF 180 GQ FRTGLL +G+P P G+ PT+A+ +K QGYATGQFGKNH+GDR+E LPT HGF Sbjct: 115 GQSCFRTGLLKVGLPAAPEGLSGKDPTLAELLKPQGYATGQFGKNHVGDRNEFLPTVHGF 174 Query: 181 DEFFGNLYHLNAEEEPEGYFYPKDPNFRKQFGPRGVIKSSA----------------DGK 224 DEFFGNLYHLNAEEEPE YPK+P F +FGPRGV+K +A K Sbjct: 175 DEFFGNLYHLNAEEEPENVDYPKNPEFHAKFGPRGVLKCTATETDDPTEDPRFGRVGKQK 234 Query: 225 IEDTGPLNTARMPTVDEEFLGAAKDFIGRQAKADKPFFVWFNSTRMHVFTHLKPASLGKT 284 IEDTGPL RM TVDEEFLGAAKDFI RQ KA KPFF WFNSTRMH+ THLKPAS GKT Sbjct: 235 IEDTGPLTKKRMETVDEEFLGAAKDFIDRQHKASKPFFCWFNSTRMHINTHLKPASEGKT 294 Query: 285 GKGIHADGMVEHDGMVGELLKQLDDLGITDNTIVLYTTDNGAEIALWPDGAMTPFHGEKG 344 G G+ ADGMVE DGMVG+LL+QLDDLGI DNTIVL+TTDNGAE+ WPDG TPFHGEK Sbjct: 295 GLGMEADGMVELDGMVGQLLQQLDDLGIADNTIVLWTTDNGAEVFSWPDGGTTPFHGEKN 354 Query: 345 TTWEGGMRIPMMVRWPGVVKPGTEYNEIISLIDWFPTLCAAAGMNDVKEKMKTGFAGAGG 404 T+WEGG R+P M+RWPGVVKPGTE N+I+S DW PTL AAAG +VKEK+ TG+ A G Sbjct: 355 TSWEGGYRVPGMIRWPGVVKPGTEINDIVSHEDWVPTLVAAAGEPNVKEKLLTGYE-AAG 413 Query: 405 KTFKVHLDGYNFMPFFKGEAKEPPRDSIYYFDQGGNLNAIRWNDWKLSFASSKGN-IATG 463 KTFKVHLDGY+ G +P ++ Y+ D+ GNL A R++ WK+ F + Sbjct: 414 KTFKVHLDGYDQHDLLAGTGPDPRKEFFYWTDE-GNLAAFRYDRWKILFLEQRAEGFDVW 472 Query: 464 TREVTAWSL--ITNLRMDPYERGLEEGGEAIKFLAQNMWLIVPVQGKIKEFFSDFDQF-P 520 A + I ++R DP+ER E E +++ ++++P Q + + F F P Sbjct: 473 EEPFVALRVPKIFDVRADPFERAQREAAEYVRWRFDRTYVLMPAQAFVGQHLQSFVAFPP 532 Query: 521 YQEGSSLNAGGI 532 Q+ S + G + Sbjct: 533 RQKPGSFSLGQV 544 >SMb20915 [P] COG3119 Arylsulfatase A and related enzymes Sme Sinorhizobium meliloti Length = 537 Score = 566 bits (1458), Expect = e-161, Method: Compositional matrix adjust. Identities = 301/513 (58%), Positives = 365/513 (71%), Gaps = 10/513 (1%) Query: 21 IDRRAVLLGTSSLAATAA-LTSQALAQAQKAAPAAAPAGGRKPNILVIFGDDIGIPQISA 79 + RR +L+ +++AATA L A+AQ A+ + GRKPNIL+I GDDIG S Sbjct: 17 LSRRDLLVAGTAMAATAVTLAGPTPAKAQAASTGGS---GRKPNILMIMGDDIGWFNPSI 73 Query: 80 YTMGMMGYRTPNIDRIAREGAIFTDAYGQQSCTAGRASFILGQEPFRTGLLTIGMPGDPH 139 Y GMMGYRTPNIDRI EGA+FTD YG+QSCTAGRA+FI GQ P RTGL +G+PG Sbjct: 74 YHRGMMGYRTPNIDRIGNEGAMFTDWYGEQSCTAGRAAFITGQSPIRTGLTKVGLPGADI 133 Query: 140 GIQDWMPTIADAMKTQGYATGQFGKNHLGDRDEHLPTKHGFDEFFGNLYHLNAEEEPEGY 199 GIQ T+A+ +K+ GYATGQFGKNHLGD+DE LPT HGFDEFFGNLYHLNAEEEPE Sbjct: 134 GIQPEDATVAELLKSLGYATGQFGKNHLGDKDEFLPTAHGFDEFFGNLYHLNAEEEPENP 193 Query: 200 FYPKDPNFRKQFGPRGVIKSSADGKIEDTGPLNTARMPTVDEEFLGAAKDFIGRQAKADK 259 YP+DP FRK+FGPRGVIK++ADGKIEDTGPL+ RM TVD+EFL AA DFI R+AK D Sbjct: 194 DYPQDPAFRKRFGPRGVIKATADGKIEDTGPLSVKRMETVDQEFLEAALDFIDRKAKGDA 253 Query: 260 PFFVWFNSTRMHVFTHLKPASLGKTGKGIHADGMVEHDGMVGELLKQLDDLGITDNTIVL 319 P+F +FNSTRMHV THLKP S GKTG G++ DGMVEHDG VGELLK+LDDLG+T+NTIV+ Sbjct: 254 PWFCYFNSTRMHVNTHLKPDSAGKTGLGVYPDGMVEHDGHVGELLKKLDDLGLTENTIVV 313 Query: 320 YTTDNGAEIALWPDGAMTPFHGEKGTTWEGGMRIPMMVRWPGVVKPGTEYNEIISLIDWF 379 YT+DNGAE+ WPDG TPF GEK T WEGG R+PM +RWPGV+KPGT +NE S D Sbjct: 314 YTSDNGAEVMTWPDGGNTPFRGEKATNWEGGFRVPMCIRWPGVIKPGTIHNEPFSHYDLI 373 Query: 380 PTLCAAAGMNDVKEKMKTGFAGAGGKTFKVHLDGYNFMPFFKGEAKEPPRDSIYYFDQGG 439 PT CAAAG D+ K TG+A AG KTFKVHLDGYN MPF G + + PR Y++ G Sbjct: 374 PTFCAAAGEPDIVAKCLTGYA-AGAKTFKVHLDGYNLMPFLSGSSNDAPRRDFLYWNDDG 432 Query: 440 NLNAIRWNDWKLSFASSKGN-IATGTREVTAWS--LITNLRMDPYERGLEEGGEAIKFLA 496 L A+R +WK+ F S I + T L+ NLR DP+ERG + E K+ Sbjct: 433 ELVAVRVQNWKVVFKSQDHEGIGVWRQPFTELRAPLLFNLRSDPFERG-DTSMEYEKWFF 491 Query: 497 QNMWLIVPVQGKIKEFFSDFDQFPY-QEGSSLN 528 +++VP Q + ++ F +FP Q+ +S N Sbjct: 492 DRSFVVVPSQAVVAKWLESFKEFPIRQKPASFN 524 >SMa0943 [P] COG3119 Arylsulfatase A and related enzymes Sme Sinorhizobium meliloti Length = 545 Score = 560 bits (1443), Expect = e-159, Method: Compositional matrix adjust. Identities = 291/517 (56%), Positives = 345/517 (66%), Gaps = 27/517 (5%) Query: 23 RRAVLLGTSSLAATAALTSQALAQAQKAAPAAAPAGGRKPNILVIFGDDIGIPQISAYTM 82 RR VLL SL A AL S A A A G+KPNILVIFGDDIG SAY Sbjct: 14 RREVLLAGGSLLAVTALGSLT------GAGAKAQTAGKKPNILVIFGDDIGWWNTSAYNR 67 Query: 83 GMMGYRTPNIDRIAREGAIFTDAYGQQSCTAGRASFILGQEPFRTGLLTIGMPGDPHGIQ 142 G MGY+TPNIDRIA EGAIFTD Y QQSCTAGRA+FI GQ FRTGLL +G+PG G+ Sbjct: 68 GQMGYQTPNIDRIADEGAIFTDLYAQQSCTAGRAAFITGQSCFRTGLLKVGLPGAKEGLS 127 Query: 143 DWMPTIADAMKTQGYATGQFGKNHLGDRDEHLPTKHGFDEFFGNLYHLNAEEEPEGYFYP 202 D PT+A+ +K GYATGQFGKNHLGDR+E LPT HGFDEFFGNLYHLNAEEEPE YP Sbjct: 128 DKDPTLAELLKPHGYATGQFGKNHLGDRNEFLPTVHGFDEFFGNLYHLNAEEEPENPDYP 187 Query: 203 KDPNFRKQFGPRGVIKSSADG----------------KIEDTGPLNTARMPTVDEEFLGA 246 KDP FR +FGPRGV++ A KIEDTGPL+ RM TVD EFLGA Sbjct: 188 KDPQFRAKFGPRGVLRCVASDTDDPTEDPRFGRVGKQKIEDTGPLDKRRMETVDGEFLGA 247 Query: 247 AKDFIGRQAKADKPFFVWFNSTRMHVFTHLKPASLGKTGKGIHADGMVEHDGMVGELLKQ 306 A +FI + KA KPFF WFN+TRMH++THLKP S GKTG G+ ADGM E DGMVG+LLKQ Sbjct: 248 AMNFIDKNQKAGKPFFCWFNATRMHIYTHLKPESQGKTGLGLVADGMTEFDGMVGQLLKQ 307 Query: 307 LDDLGITDNTIVLYTTDNGAEIALWPDGAMTPFHGEKGTTWEGGMRIPMMVRWPGVVKPG 366 LDDLGI DNTIVL+TTDNGAE+ WPDG TPFHGEK T WEGG R+P ++RWPGV+KPG Sbjct: 308 LDDLGIADNTIVLFTTDNGAEVFSWPDGGSTPFHGEKNTNWEGGYRVPGVMRWPGVIKPG 367 Query: 367 TEYNEIISLIDWFPTLCAAAGMNDVKEKMKTGFAGAGGKTFKVHLDGYNFMPFFKGEAKE 426 TE N+I+S DW PT AAAG DVK+K+ TG+ A GKTFKVHLDGYN G Sbjct: 368 TEINDIVSHEDWVPTFVAAAGEPDVKQKLLTGYE-AAGKTFKVHLDGYNQRELLAGSGPS 426 Query: 427 PPRDSIYYFDQGGNLNAIRWNDWKLSFASSKG---NIATGTREVTAWSLITNLRMDPYER 483 ++ Y+ D GNL A+R++ WKL F + ++ + + +LR DP+E Sbjct: 427 SRKEYFYWTDD-GNLAALRYDRWKLVFMEQRAEGLDVWQDPLITLRFPKLIDLRADPFEI 485 Query: 484 GLEEGGEAIKFLAQNMWLIVPVQGKIKEFFSDFDQFP 520 G+ ++ ++ + +VP Q + + FP Sbjct: 486 AQHVAGDYDRWRVEHAFALVPAQAFVVRHLQTYVDFP 522 >MA2648 [P] COG3119 Arylsulfatase A and related enzymes Mac Methanosarcina acetivorans str.C2A Length = 535 Score = 541 bits (1393), Expect = e-153, Method: Compositional matrix adjust. Identities = 276/510 (54%), Positives = 341/510 (66%), Gaps = 17/510 (3%) Query: 42 QALAQAQKAAPAAAPAGGRKPNILVIFGDDIGIPQISAYTMGMMGYRTPNIDRIAREGAI 101 +AL QA + +KPNILVI+GDDIGI +S Y+ G+MGYRTPNIDRIA EG Sbjct: 25 KALIQALNQSIWGLRMTEKKPNILVIWGDDIGISNLSCYSDGLMGYRTPNIDRIANEGMR 84 Query: 102 FTDAYGQQSCTAGRASFILGQEPFRTGLLTIGMPGDPHGIQDWMPTIADAMKTQGYATGQ 161 FTD+YG+QSCTAGRA+FI GQ FRTGL +GMPG G+Q PTIA+ +K GYATGQ Sbjct: 85 FTDSYGEQSCTAGRAAFITGQSVFRTGLSKVGMPGAKIGLQPEDPTIAELLKPLGYATGQ 144 Query: 162 FGKNHLGDRDEHLPTKHGFDEFFGNLYHLNAEEEPEGYFYPKD---PNFRKQFGPRGVIK 218 FGKNH GD DE LPT HGFDEFFGNLYHLNAEEEPE YP + PNFRK +GPRGVI+ Sbjct: 145 FGKNHFGDLDEFLPTNHGFDEFFGNLYHLNAEEEPEKRDYPPEKDFPNFRKNYGPRGVIR 204 Query: 219 SSADGKIEDTGPLNTARMPTVDEEFLGAAKDFIGRQAKADKPFFVWFNSTRMHVFTHLKP 278 S ADG+IEDTGPL RM D+EFL A DFI RQ +A+KPFFVWFN+TRMH TH+ Sbjct: 205 SYADGRIEDTGPLTKKRMEEADQEFLDATIDFIKRQHEAEKPFFVWFNTTRMHFRTHIPD 264 Query: 279 ASLGKTGK--GIHADGMVEHDGMVGELLKQLDDLGITDNTIVLYTTDNGAEIALWPDGAM 336 G++G+ + D M+EHD +G LL LD++GI D+TIVLY+TDNG + WPD AM Sbjct: 265 RIRGQSGRWQSAYHDAMIEHDRQIGVLLDLLDEIGIADDTIVLYSTDNGPHMNSWPDAAM 324 Query: 337 TPFHGEKGTTWEGGMRIPMMVRWPGVVKPGTEYNEIISLIDWFPTLCAAAGMNDVKEKMK 396 TPF EK + WEG R+P ++RWPG + G NE +S +DW PTL AAA D+KEK+K Sbjct: 325 TPFRNEKDSCWEGAFRVPELIRWPGKIPAGKVSNEFVSHLDWLPTLLAAAEEPDIKEKLK 384 Query: 397 TGFAGAGGKTFKVHLDGYNFMPFFKGEAKEPPRDSIYYFDQGGNLNAIRWNDWKLSFASS 456 G AG KTFKVHLDGYN +P+ G+ K+ PR +YF GG+L AIR+++WKL F Sbjct: 385 KGHK-AGDKTFKVHLDGYNLLPYLTGKEKKSPRTEFFYFSDGGDLMAIRYDNWKLVFLEQ 443 Query: 457 KGNIATGTREVTAWSL-------ITNLRMDPYERGLEEGGEAIKFLAQNMWLIVPVQGKI 509 + ATGT V A I NLR DPYER +L + +L+VP QG + Sbjct: 444 R---ATGTLLVWAEPFVPLRVPKIFNLRTDPYERADRTSNTYYDWLLDHAFLVVPAQGVV 500 Query: 510 KEFFSDFDQF-PYQEGSSLNAGGINYGLLR 538 +F + F +F P Q+ +S + LL+ Sbjct: 501 GDFLATFKEFPPRQKAASFTVDQVMEKLLQ 530 >SMb20332 [P] COG3119 Arylsulfatase A and related enzymes Sme Sinorhizobium meliloti Length = 313 Score = 226 bits (577), Expect = 9e-59, Method: Compositional matrix adjust. Identities = 108/153 (70%), Positives = 129/153 (84%), Gaps = 2/153 (1%) Query: 402 AGGKTFKVHLDGYNFMPFFKGEAKEPPRDSIYYFDQGGNLNAIRWNDWKLSFA-SSKGNI 460 +G K FKVHLDGYN KGEAKEPPR+++YYFDQGGNLNAIRWNDWKLSFA +S+GNI Sbjct: 157 SGDKDFKVHLDGYNLTEL-KGEAKEPPREAVYYFDQGGNLNAIRWNDWKLSFAINSEGNI 215 Query: 461 ATGTREVTAWSLITNLRMDPYERGLEEGGEAIKFLAQNMWLIVPVQGKIKEFFSDFDQFP 520 AT TRE +W+ ITNLRMDPYERG +EGG A++F+ +NMWL+VP+QGKIKEF DFDQ+P Sbjct: 216 ATATRETPSWANITNLRMDPYERGAKEGGGAMEFIGRNMWLLVPIQGKIKEFSQDFDQYP 275 Query: 521 YQEGSSLNAGGINYGLLRQQAALKRLNDLERLK 553 YQ GS+LNA GI+Y L+QQAALKRL +L L+ Sbjct: 276 YQPGSTLNASGISYTWLQQQAALKRLGELGELE 308 Score = 219 bits (557), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 103/126 (81%), Positives = 111/126 (88%), Gaps = 1/126 (0%) Query: 116 ASFILGQEPFRTGLLTIGMPGDPHGIQDWMPTIADAMKTQGYATGQFGKNHLGDRDEHLP 175 ASFILGQE FR GLLTIGMPGDPHGI+DWMPTIAD +K++GYATGQFGKNHLG+RDEHLP Sbjct: 10 ASFILGQEQFRMGLLTIGMPGDPHGIRDWMPTIADVVKSKGYATGQFGKNHLGERDEHLP 69 Query: 176 TKHGFDEFFGNLYHLNAEEEPEGYFYPKDPNFRKQF-GPRGVIKSSADGKIEDTGPLNTA 234 T HGFDEFFGNLYHLNAEEEPEGYFYPKD FR++ R I+SSADGKIEDTG LNT Sbjct: 70 TNHGFDEFFGNLYHLNAEEEPEGYFYPKDEEFREELRAAREFIESSADGKIEDTGALNTK 129 Query: 235 RMPTVD 240 RM TVD Sbjct: 130 RMETVD 135