BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0048.p (287 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll1068 [I] COG1562 Phytoene/squalene synthetase Mlo Mesorhizobi... 164 2e-40 BMEI1074 [I] COG1562 Phytoene/squalene synthetase Bme Brucella m... 162 7e-40 AGc2873 [I] COG1562 Phytoene/squalene synthetase Atu Agrobacteri... 147 3e-35 SMc02055 [I] COG1562 Phytoene/squalene synthetase Sme Sinorhizob... 144 2e-34 NMB1168 [I] COG1562 Phytoene/squalene synthetase Nme Neisseria m... 71 3e-12 >mll1068 [I] COG1562 Phytoene/squalene synthetase Mlo Mesorhizobium loti Length = 301 Score = 164 bits (415), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 107/275 (38%), Positives = 146/275 (53%), Gaps = 9/275 (3%) Query: 11 AAFCADLVRSHDFVRYASTLFLPGPERRAMLAIYAFNIEVSRVHEQVSQPLPGEMRLQWW 70 A D VR+ D RY + L+ P +R A+ ++YAFN E++ + +++ + LPGE+RLQWW Sbjct: 24 AKIVMDAVRAADHDRYLTALYAPADKREALFSLYAFNAEIAGIRDRIHEALPGEVRLQWW 83 Query: 71 TDMLAGAGHGGVEGNPVAAELLHTIRNHRLPVSPFSLLVEEHQFDLYNDPMPSLTALEGY 130 D++A + G+PVA L TI H LP F ++E FDLY+DPMPS T LEGY Sbjct: 84 RDLIAADNDAAI-GHPVADALKATISGHHLPKLAFDNMLEARIFDLYDDPMPSRTDLEGY 142 Query: 131 LDATASVLFSQATRVVARPSEA--IDHLARHAGLAQGMAQVIASLGRDASRQQLFLPLQL 188 TA+ L A V+ P EA LA AG AQ M ++ L R Q F+P + Sbjct: 143 CGETAAALIQLAAMVL-DPVEAPRFAELAGRAGCAQAMTGLLLLLPLHRKRGQCFVPADI 201 Query: 189 LQQPGGSKEEVFAGKMTPNIRAAIDQLADAAQGHLKTAFGLLADVPSGVRPIFLPLACVR 248 L G S EE AG P + A+ + A+ HL A++P+ +RP FLPLA R Sbjct: 202 LAAAGSSPEEFVAGDGGPGAQRAVAAMIALAREHLSAFEQGAAELPASLRPAFLPLALSR 261 Query: 249 RELNR---ARREDYDPFLPKPVSRLRTLWTLWRAA 280 L+R AR+ D +S LR W L R A Sbjct: 262 AYLDRTEGARQSTLDGV--ARLSALRRHWLLVRRA 294 >BMEI1074 [I] COG1562 Phytoene/squalene synthetase Bme Brucella melitensis Length = 277 Score = 162 bits (410), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 97/268 (36%), Positives = 143/268 (53%), Gaps = 2/268 (0%) Query: 14 CADLVRSHDFVRYASTLFLPGPERRAMLAIYAFNIEVSRVHEQVSQPLPGEMRLQWWTDM 73 C L+R D RY S L+ P +R A+ A+YAFN E++R+ + V +PLPGE+RLQWW D+ Sbjct: 8 CLALLREADRDRYLSVLYAPQEKRGALAALYAFNAEIARIRDLVHEPLPGEVRLQWWRDL 67 Query: 74 LAGAGHGGVEGNPVAAELLHTIRNHRLPVSPFSLLVEEHQFDLYNDPMPSLTALEGYLDA 133 + G G E +PVAA L+ TI + LP F E FDLY+DPMPS LEGY Sbjct: 68 INGEARGSAEAHPVAAALIETIEKYELPRIAFDNYCEARVFDLYDDPMPSRNDLEGYCGE 127 Query: 134 TASVLFSQATRVVAR-PSEAIDHLARHAGLAQGMAQVIASLGRDASRQQLFLPLQLLQQP 192 TAS L A ++ R ++A A HAG+AQ +A ++ L R Q+++P +L+ Sbjct: 128 TASALIQLAGFILDRDAAQAHAETAGHAGVAQAVAGLLRLLPIHRRRGQVYVPADMLKAI 187 Query: 193 GGSKEEVFAGKMTPNIRAAIDQLADAAQGHLKTAFGLLADVPSGVRPIFLPLACVRRELN 252 G +++ + + + A+ + A+ HL A +P + P FLP+A V LN Sbjct: 188 GVTRDMLLSSEDKSATERAVTIMLALAREHLAIFDKAKAGLPQTLHPAFLPMALVPAYLN 247 Query: 253 RARREDYDPFLP-KPVSRLRTLWTLWRA 279 R +S +R W ++RA Sbjct: 248 AVERLGAQAAQKVADISAIRKQWLMFRA 275 >AGc2873 [I] COG1562 Phytoene/squalene synthetase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 281 Score = 147 bits (370), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 95/281 (33%), Positives = 145/281 (51%), Gaps = 4/281 (1%) Query: 7 PKDGAAFCADLVRSHDFVRYASTLFLPGPERRAMLAIYAFNIEVSRVHEQVSQPLPGEMR 66 P + C +R D RY + L P +R A+ A+YAFN E++R+ + V + LPGE+R Sbjct: 3 PTENLDVCLATLRDTDRDRYLACLLSPADKRNALAALYAFNAEIARIRDSVREALPGEVR 62 Query: 67 LQWWTDMLAGAGHGGVEGNPVAAELLHTIRNHRLPVSPFSLLVEEHQFDLYNDPMPSLTA 126 +QWW D++ G HG + +PVAA LL TI ++RLP ++E FDLY+D A Sbjct: 63 MQWWRDLVDGNPHGDSQSHPVAAALLTTIEHYRLPRPVLGNMIEARIFDLYDDLFEDRNA 122 Query: 127 LEGYLDATASVLFSQATRVVARPSEAID-HLARHAGLAQGMAQVIASLGRDASRQQLFLP 185 LEGY TAS L A+ V++ A A HAG+AQ MA ++ + R Q+++P Sbjct: 123 LEGYAGETASALIQLASLVLSAEDAAHSAEAAGHAGVAQAMAGMLLLMPLHRRRGQVYIP 182 Query: 186 LQLLQQPGGSKEEVFAGKMTPNIRAAIDQLADAAQGHLKTAFGLLADVPSGVRPIFLPLA 245 +L G +E AG+ I A++ A A H++ A A + + +LP+A Sbjct: 183 ADMLAAAGLDRETFLAGQDRQRIGIAVEIFAAHALDHIEKARR--ATISKNLFAAYLPVA 240 Query: 246 CVRRELNRARREDYDPFLPK-PVSRLRTLWTLWRAARTEEF 285 + AR+ F +S+LR W L +A+ + F Sbjct: 241 LSGPVIAAARKAGAGVFDGDLQLSQLRRQWLLAKASFLKRF 281 >SMc02055 [I] COG1562 Phytoene/squalene synthetase Sme Sinorhizobium meliloti Length = 280 Score = 144 bits (363), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 95/280 (33%), Positives = 138/280 (49%), Gaps = 23/280 (8%) Query: 18 VRSHDFVRYASTLFLPGPERRAMLAIYAFNIEVSRVHEQVSQPLPGEMRLQWWTDMLAGA 77 +R D RY + L P +R ++ A+YAF E++RV + V +PLPGE+RLQWW D L Sbjct: 12 LRDTDRDRYLACLLSPAEKRHSLAALYAFYAEIARVRDMVKEPLPGEIRLQWWRDTLENE 71 Query: 78 GHGGVEGNPVAAELLHTIRNHRLPVSPFSLLVEEHQFDLYNDPMPSLTALEGYLDATASV 137 G G+P+A LL IR H LPV +++ FDLY+DPM ALEGY TAS Sbjct: 72 QSDGA-GHPLAEALLRCIREHHLPVRVLQDMIDARIFDLYDDPMQDRAALEGYAGETASA 130 Query: 138 LFSQATRVV-----ARPSEAIDHLARHAGLAQGMAQVIASLGRDASRQQLFLPLQLLQQP 192 L ++ ++ AR ++A A HAG+AQ +A ++ L R Q++LP +LL Sbjct: 131 LIQLSSLILDPDNAARSADA----AGHAGVAQTVAGLLLLLPVHVGRGQVYLPAELLSAT 186 Query: 193 GGSKEEVFAGKMTPNIRAAIDQLADAAQGHLKTAFGLLADVPSGVRPIFLPLACVRRELN 252 G +E + AG I A+ + HL A + F+P+A + Sbjct: 187 GLDRETLLAGTDESAIERAVRAFCGLGRDHLAKAREGAGAISGRNFSAFIPVALAEPVFD 246 Query: 253 RAR-------REDYDPFLPKPVSRLRTLWTLWRAARTEEF 285 RA R+ P + + W +WRA+R EF Sbjct: 247 RAEAAGARILRQSLQP------PQWQRQWRMWRASRRREF 280 >NMB1168 [I] COG1562 Phytoene/squalene synthetase Nme Neisseria meningitidis MC58 Length = 290 Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 54/221 (24%), Positives = 89/221 (40%) Query: 31 FLPGPERRAMLAIYAFNIEVSRVHEQVSQPLPGEMRLQWWTDMLAGAGHGGVEGNPVAAE 90 FL +R A+ +YAF E+ V ++ S P + L WW L G + +PV Sbjct: 24 FLTQEKRDAVTVLYAFCRELDDVVDECSNPDVAQATLNWWRGDLDKVFGGAMPEHPVNQA 83 Query: 91 LLHTIRNHRLPVSPFSLLVEEHQFDLYNDPMPSLTALEGYLDATASVLFSQATRVVARPS 150 L +LP L++ Q DL S L+ Y A V+ R++ Sbjct: 84 LRQVKETFKLPKYELEALIDGMQMDLVQARYGSFEELKLYCHRVAGVVGCLIARILGFSD 143 Query: 151 EAIDHLARHAGLAQGMAQVIASLGRDASRQQLFLPLQLLQQPGGSKEEVFAGKMTPNIRA 210 + A GLA + +I +G DA R +++LP++ +++ + T N Sbjct: 144 DQTLEYADKMGLALQLTNIIRDVGEDARRGRIYLPMEEMRRFDVPASVILQCSPTGNFAE 203 Query: 211 AIDQLADAAQGHLKTAFGLLADVPSGVRPIFLPLACVRREL 251 + A+ + A LL D + + L +A V EL Sbjct: 204 LMAFQIKRARETYREAVSLLPDADKKAQKVGLVMAAVYYEL 244