BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0026.p (383 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0204 [F] COG0213 Thymidine phosphorylase Rso Ralstonia solana... 256 6e-68 PH1598 [F] COG0213 Thymidine phosphorylase Pho Pyrococcus horiko... 225 1e-58 MJ0667 [F] COG0213 Thymidine phosphorylase Mja Methanococcus jan... 223 4e-58 AF1341 [F] COG0213 Thymidine phosphorylase Afu Archaeoglobus ful... 221 3e-57 PAB1982 [F] COG0213 Thymidine phosphorylase Pab Pyrococcus abyssi 219 1e-56 >RSc0204 [F] COG0213 Thymidine phosphorylase Rso Ralstonia solanacearum Length = 507 Score = 256 bits (654), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 156/338 (46%), Positives = 208/338 (61%), Gaps = 11/338 (3%) Query: 9 LPHMIEIKPTRHELKSRRINLDTGRENVAVISRRSTALRPEVFRGFSRVELRSNSKVLLA 68 LP + KP + +DT +E+V + R E F +RVE+R + L+A Sbjct: 10 LPDRLTFKP---------LGIDTWQEHVIYMHPDCAICRAEGFTAQARVEVRIGLRSLIA 60 Query: 69 TLLLTDDDSLVGPNELGLAEPAFHRFAEPVGTYVSVTPAPSPASLDAVRAKIQGRTLGAS 128 TL L L+ E+ L+ A G V+V+ AP+ SL AVRAKI G L Sbjct: 61 TLNLVGS-GLLEMCEVSLSVSAVETLMARPGDIVTVSHAPALESLRAVRAKIYGAHLDTH 119 Query: 129 DIDAIVEDLTHFRYSDMEIAAFLVSSAG-FMTSGELLALTRAMSKAGTQLKWNANVIVDK 187 + ++V D+ RY+D+ IAAFL + AG M+ E + LT+AM +G L+W+ ++ DK Sbjct: 120 QLASVVGDIAKERYADVHIAAFLSACAGGRMSVKETIDLTQAMVDSGECLEWDREIVADK 179 Query: 188 HCIGGIPGNRTSMIVVPIVAAHGLTIPKTSSRAITSPAGTADTMEVLARVDLSVEAMKEV 247 HC+GG+PGNRTS IVV I AA GL +PKTSSRAITSPAGTADTME L RV LS ++ V Sbjct: 180 HCVGGLPGNRTSPIVVAIAAAAGLLLPKTSSRAITSPAGTADTMETLTRVALSATELRRV 239 Query: 248 VAACNGCLVWGGHVNLSPADDILIGVERPLSLDAHEQMVASILSKKLAAGSTHLLIDLPI 307 V L WGG ++LSPADD+LI VER L +D+ Q+ ASILSKK+AAGSTH+LID+P+ Sbjct: 240 VDRVGASLAWGGALSLSPADDVLIRVERALDVDSDAQLAASILSKKIAAGSTHVLIDVPV 299 Query: 308 GPNAKLTSASEAMRLRKLFEFVGDHFGIETEVVTTEAA 345 GP AK+ S + RLR L E V FG+ +V T+ + Sbjct: 300 GPTAKVRSLQDLERLRMLLERVARSFGVRVTIVRTDGS 337 >PH1598 [F] COG0213 Thymidine phosphorylase Pho Pyrococcus horikoshii Length = 503 Score = 225 bits (574), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 129/321 (40%), Positives = 192/321 (59%), Gaps = 7/321 (2%) Query: 23 KSRRINLDTGRENVAVISRRSTALRPEVFRGFSRVELRSNSKVLLATLLLTDDDSLVGPN 82 K + + + TG NV + R + + V++ S + + A++ + D + Sbjct: 4 KVKILKIKTGSFNVFISPRDAEEWK---LHPNDLVKIESGKRSIYASVAIGD---FIEDG 57 Query: 83 ELGLAEPAFHRFAEPVGTYVSVTPAPSPASLDAVRAKIQGRTLGASDIDAIVEDLTHFRY 142 E+GL++ + G VS+TP+ +P S+ ++ K++G L +I+ I+ D+ + Sbjct: 58 EVGLSQDILSSYQFSEGEVVSITPSGTPESVKYIKKKMKGEKLRKVEIETIIRDIVDRKL 117 Query: 143 SDMEIAAFLVS-SAGFMTSGELLALTRAMSKAGTQLKWNANVIVDKHCIGGIPGNRTSMI 201 + EI+AF+ + ++ E+ ALT AM++ G L + I+D H IGG+PGN+T+++ Sbjct: 118 RNTEISAFITAIEINGLSMDEIAALTIAMAETGDMLDIDRKPIMDVHSIGGVPGNKTNIL 177 Query: 202 VVPIVAAHGLTIPKTSSRAITSPAGTADTMEVLARVDLSVEAMKEVVAACNGCLVWGGHV 261 VVPIVAA GLTIPKTSSRAITS AGTAD +EVL V LS++ +K +V CLVWGG + Sbjct: 178 VVPIVAAAGLTIPKTSSRAITSAAGTADVVEVLTNVKLSLDEIKRIVEKIGACLVWGGAL 237 Query: 262 NLSPADDILIGVERPLSLDAHEQMVASILSKKLAAGSTHLLIDLPIGPNAKLTSASEAMR 321 NL+PADD+ I VER LSLD M+ASI+SKK A GS ++LID+P G AK+ + EA Sbjct: 238 NLAPADDLTIHVERRLSLDPRGLMLASIMSKKYAIGSQYILIDIPTGKGAKVETMDEART 297 Query: 322 LRKLFEFVGDHFGIETEVVTT 342 L K F +G G EV T Sbjct: 298 LAKDFIELGKKLGQYVEVAIT 318 >MJ0667 [F] COG0213 Thymidine phosphorylase Mja Methanococcus jannaschii Length = 503 Score = 223 bits (569), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 129/322 (40%), Positives = 191/322 (59%), Gaps = 8/322 (2%) Query: 22 LKSRRINLDTGRENVAVISRRSTALRPEVFRGFSRVELRSNSKVLLATLLLTDDDSLVGP 81 LK R +++D EN+ +I+ S L+ + RV + K ++ +L +L+ Sbjct: 4 LKVRVLDIDL--ENLVLIN--SEDLKSSQYFPQDRVVVEFKGKEVIG--ILHSSTTLINR 57 Query: 82 NELGLAEPAFHRFAEPVGTYVSVTPAPSPASLDAVRAKIQGRTLGASDIDAIVEDLTHFR 141 E+GL + G V++ A P SL +R K+ G L +I I++++ + Sbjct: 58 GEIGLPQKVVKELGVKEGDIVTIKHAEKPKSLPYIRKKMDGNKLKKEEIFEIIDEMVDGK 117 Query: 142 YSDMEIAAFLVS-SAGFMTSGELLALTRAMSKAGTQLKWNANVIVDKHCIGGIPGNRTSM 200 +++EI+AF+ S M E+ A+T M++ G + W + I D H IGG+PGN+ ++ Sbjct: 118 LTNIEISAFVTSLYINGMDMDEIEAMTIRMAETGEMVNWEGH-IFDVHSIGGVPGNKYAL 176 Query: 201 IVVPIVAAHGLTIPKTSSRAITSPAGTADTMEVLARVDLSVEAMKEVVAACNGCLVWGGH 260 +VVPIVA+ GL IPKTSSRAITS AGTAD +EVL RVDL++E +K VV NGC+VWGG Sbjct: 177 LVVPIVASAGLKIPKTSSRAITSAAGTADVVEVLTRVDLTIEEIKRVVKETNGCMVWGGA 236 Query: 261 VNLSPADDILIGVERPLSLDAHEQMVASILSKKLAAGSTHLLIDLPIGPNAKLTSASEAM 320 ++L+PADDI I VERPL +D +++S+++KKLA G LLID+P G AK+ S EA Sbjct: 237 LDLAPADDITINVERPLGIDPEPLLLSSVMAKKLAMGVNKLLIDIPTGYGAKVKSIKEAS 296 Query: 321 RLRKLFEFVGDHFGIETEVVTT 342 L + F + D I TE T Sbjct: 297 SLARKFIELSDRLRIVTECAIT 318 >AF1341 [F] COG0213 Thymidine phosphorylase Afu Archaeoglobus fulgidus Length = 504 Score = 221 bits (562), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 126/315 (40%), Positives = 191/315 (60%), Gaps = 6/315 (1%) Query: 22 LKSRRINLDTGRENVAVISRRSTALRPEVFRGFSRVELRSNSKVLLATLLLTDDDSLVGP 81 K+ R+ +GR AVI A V G RV +R ++AT+ +T + +V Sbjct: 3 FKAVRVPFKSGR--FAVILNEEDASELGVREG-DRVRVRYGKAGVVATVQITRE--IVEK 57 Query: 82 NELGLAEPAFHRFAEPVGTYVSVTPAPSPASLDAVRAKIQGRTLGASDIDAIVEDLTHFR 141 +GL + A G V V P+P P S++ ++ K +G L +I IVED+T+ Sbjct: 58 GFVGLTDLASMELGISDGAEVDVFPSPKPKSVELIKKKTRGEKLSQDEIRRIVEDITNNA 117 Query: 142 YSDMEIAAFLVSSA-GFMTSGELLALTRAMSKAGTQLKWNANVIVDKHCIGGIPGNRTSM 200 S++E+ AF++SS M E+ LTR+M + G +++++ +VDKH IGG+PGN+ S+ Sbjct: 118 LSEVELTAFVISSMLRGMDFDEIEWLTRSMIETGERIEFDRGTVVDKHSIGGVPGNKISL 177 Query: 201 IVVPIVAAHGLTIPKTSSRAITSPAGTADTMEVLARVDLSVEAMKEVVAACNGCLVWGGH 260 ++VP VAA GL IPKT+SRAITS +GTADTMEVLA V+LSV+ +KE+ G + WGG Sbjct: 178 LIVPTVAAAGLLIPKTASRAITSASGTADTMEVLANVNLSVDEIKEITERVGGVIAWGGA 237 Query: 261 VNLSPADDILIGVERPLSLDAHEQMVASILSKKLAAGSTHLLIDLPIGPNAKLTSASEAM 320 N++PADD +I VE PLS+D Q++AS+++KK + G+ H++ID+P+G AK+ Sbjct: 238 TNIAPADDKIIRVEHPLSIDPRPQLLASVMAKKGSVGAKHVVIDIPVGEGAKIEKVEVGR 297 Query: 321 RLRKLFEFVGDHFGI 335 L F +G G+ Sbjct: 298 SLANDFIELGRRLGL 312 >PAB1982 [F] COG0213 Thymidine phosphorylase Pab Pyrococcus abyssi Length = 507 Score = 219 bits (557), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 123/287 (42%), Positives = 176/287 (61%), Gaps = 4/287 (1%) Query: 57 VELRSNSKVLLATLLLTDDDSLVGPNELGLAEPAFHRFAEPVGTYVSVTPAPSPASLDAV 116 V++ S + + ++++ D V E+GL+ + G VS+TP+ +P S+ + Sbjct: 39 VKIESGKRSIYGSVVIGD---FVESGEVGLSLDILDAYQFSEGELVSITPSETPESVRYI 95 Query: 117 RAKIQGRTLGASDIDAIVEDLTHFRYSDMEIAAFLVS-SAGFMTSGELLALTRAMSKAGT 175 + K++G L +I+ IV D+ + + EI+A + + + E+ ALT AM++ G Sbjct: 96 KKKMRGEKLRKVEIETIVRDIVDRKLRNTEISALVTAIEVNGLDMDEIAALTIAMAETGD 155 Query: 176 QLKWNANVIVDKHCIGGIPGNRTSMIVVPIVAAHGLTIPKTSSRAITSPAGTADTMEVLA 235 L + I+D H IGG+PGN+T++IVVPIVAA GLTIPKTSSRAITS AGTAD +EV Sbjct: 156 MLDIDRKPIMDVHSIGGVPGNKTNIIVVPIVAAAGLTIPKTSSRAITSAAGTADVVEVFT 215 Query: 236 RVDLSVEAMKEVVAACNGCLVWGGHVNLSPADDILIGVERPLSLDAHEQMVASILSKKLA 295 V LS++ +K +V CLVWGG +NL+PADD+ I VER LSLD M+ASI+SKK A Sbjct: 216 NVTLSLDEIKRIVEKIGACLVWGGALNLAPADDLTIHVERRLSLDPRGLMLASIMSKKYA 275 Query: 296 AGSTHLLIDLPIGPNAKLTSASEAMRLRKLFEFVGDHFGIETEVVTT 342 GS ++LID+P G AK+ + EA L K F +G G EV T Sbjct: 276 IGSQYILIDIPTGKGAKVETMEEARSLAKDFIELGKKLGQYVEVAIT 322