BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0030.0025.p         (197 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

MA1774 [C] COG0778 Nitroreductase Mac Methanosarcina acetivorans...   120   2e-27
AF2267 [C] COG0778 Nitroreductase Afu Archaeoglobus fulgidus           75   1e-13
MA0330 [C] COG0778 Nitroreductase Mac Methanosarcina acetivorans...    70   3e-12
MTH120 [C] COG0778 Nitroreductase Mth Methanothermobacter therma...    69   5e-12
TM0383 [C] COG0778 Nitroreductase Tma Thermotoga maritima              69   7e-12

>MA1774 [C] COG0778 Nitroreductase Mac Methanosarcina acetivorans str.C2A
          Length = 220

 Score =  120 bits (301), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 67/191 (35%), Positives = 109/191 (57%), Gaps = 16/191 (8%)

Query: 13  IYKRRAVRSYTPEKLERATIKHLLDAAVQAPTALHAEPWAFVVIQDKVRLRRYSDRAKTL 72
           IY+RR+VR+Y+ +++    IK ++ A   AP+A++ +PW FVV++++  + +Y D A+  
Sbjct: 38  IYQRRSVRNYSDKEVSDEIIKEIIRAGTYAPSAVNKQPWRFVVVKNRQLIDKYDDLARKA 97

Query: 73  LL------DQQQAISHLQSAEPQALAMLSNPDFNIFYDASALIVVCCKAKGPFVEADCWL 126
            L      D    I ++Q         LS P   I Y A   I+V   A     + DC L
Sbjct: 98  FLSVYGDTDNPDLIGYVQ--------YLSKPTTRILYGAPVFILVFA-APDVIDDRDCAL 148

Query: 127 AAENLMLAATAEGLGTCCIGFAVGILNMPDVKAELGIPEGGAAVAPIIVGFP-REIASSG 185
           AAEN+MLAA + G+G+C IG A G+ +  +   E+G+PEG   +AP+I G+P ++   + 
Sbjct: 149 AAENMMLAARSLGIGSCWIGLAAGLGSDTEFLKEVGVPEGYKLIAPLIFGYPAKDNQKAP 208

Query: 186 SRKPPVVLRWV 196
           +R   V+L+WV
Sbjct: 209 ARNADVILKWV 219


>AF2267 [C] COG0778 Nitroreductase Afu Archaeoglobus fulgidus
          Length = 174

 Score = 74.7 bits (182), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 52/178 (29%), Positives = 87/178 (48%), Gaps = 32/178 (17%)

Query: 8   DTVTAIYKRRAVRSYTPEKLERATIKHLLDAAVQAPTALHAEPWAFVVIQDKVRLRRYSD 67
           + +  IY RR++R Y+  ++    I+ +L AA+ AP+A + +PW F+V++D+  L++ S 
Sbjct: 3   ECLKMIYTRRSIRVYSDRQISDEDIEKILKAAMLAPSAGNEQPWHFIVVRDREMLKKMS- 61

Query: 68  RAKTLLLDQQQAISHLQSAEPQALAMLSNPDFNIFYDASALIVVCCKAKGPFVEADCWL- 126
                     +A +  Q        ML N        ASA IVVC   K      D W+ 
Sbjct: 62  ----------EAFTFGQ--------MLPN--------ASAAIVVCADPKLSKYPYDMWVQ 95

Query: 127 ----AAENLMLAATAEGLGTCCIGFAVGILNMPDVKAELGIPEGGAAVAPIIVGFPRE 180
               A EN++LAA   G+G+  +G       M  ++  LGIPE     + + +G+P++
Sbjct: 96  DCSAATENILLAARCLGIGSVWLGVYPREERMKALRELLGIPENIVVFSVVSLGYPKD 153


>MA0330 [C] COG0778 Nitroreductase Mac Methanosarcina acetivorans str.C2A
          Length = 179

 Score = 70.1 bits (170), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 53/180 (29%), Positives = 84/180 (46%), Gaps = 33/180 (18%)

Query: 6   KLDTVTAIYKRRAVRSYTPEKLERATIKHLLDAAVQAPTALHAEPWAFVVIQDKVRLRRY 65
            ++T+ AI+ RR++R YT   + R  +  LL AA+ AP+A++A+PW F+VI D+      
Sbjct: 5   NMETLEAIHTRRSIRKYTDRPVPRELVTELLRAAMNAPSAVNAQPWIFIVIDDRK----- 59

Query: 66  SDRAKTLLLDQQQAISHLQSAEPQALAMLSNPDFNIFYDASALIVVCC-----KAKGPFV 120
                  +LD+    S               P   +  +A   I+VC      KA G +V
Sbjct: 60  -------ILDEIPTFS---------------PYAGMCGEAPLAILVCGDTTLEKAPGYWV 97

Query: 121 EADCWLAAENLMLAATAEGLGTCCIGFAVGILNMPDVKAELGIPEGGAAVAPIIVGFPRE 180
           + DC  A +NL+LAA   GLG    G       +   +   G+P+    +  + VG+P E
Sbjct: 98  Q-DCSAAIQNLLLAAHDAGLGAVWTGIFPMTDRVKGFRKTFGLPDYVFPLGLVPVGYPAE 156


>MTH120 [C] COG0778 Nitroreductase Mth Methanothermobacter
           thermautotrophicus
          Length = 191

 Score = 69.3 bits (168), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 51/187 (27%), Positives = 86/187 (45%), Gaps = 33/187 (17%)

Query: 5   SKLDTVTAIYKRRAVRSYTPEKLERATIKHLLDAAVQAPTALHAEPWAFVVIQDKVRLRR 64
           SK+D + AI  RR++R Y   ++    I  +LDAA+  P+A+   PW F+V++++  L +
Sbjct: 21  SKMDVLEAIKTRRSIRKYQDREVPEELIDKILDAAMCGPSAVDERPWHFIVVRNREMLEK 80

Query: 65  YSDRAKTLLLDQQQAISHLQSAEPQALAMLSNPDFNIFYDASALIVVCCKA---KGP-FV 120
             +                            +P   +  DA   I+VCC +   K P F 
Sbjct: 81  IPE---------------------------VHPYGAMVKDAPVAIIVCCDSSLEKIPGFW 113

Query: 121 EADCWLAAENLMLAATAEGLGTCCIGFAVGILNMPDVKAELGIPEGGAAVAPIIVGFPRE 180
             DC +A++N++LAA + GLG    G       +  ++    IPE     + I +G+P E
Sbjct: 114 VQDCSIASQNILLAAHSLGLGAVWTGVYPLEDRVEGIRRLFSIPEHVIPFSVIPLGYPAE 173

Query: 181 IASSGSR 187
             + G+R
Sbjct: 174 --NPGTR 178


>TM0383 [C] COG0778 Nitroreductase Tma Thermotoga maritima
          Length = 166

 Score = 68.9 bits (167), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 50/176 (28%), Positives = 85/176 (48%), Gaps = 33/176 (18%)

Query: 10  VTAIYKRRAVRSYTPEKLERATIKHLLDAAVQAPTALHAEPWAFVVIQDKVRLRRYSDRA 69
           ++ IY+RR++R Y  + +    +K ++ AA+ AP+A + +PW FVVI+++          
Sbjct: 1   MSIIYRRRSIRKYQKKDVPDELVKEIIRAAMHAPSACNQQPWHFVVIRNE---------- 50

Query: 70  KTLLLDQQQAISHLQSAEPQALAMLSNPDFNIFYDASALIVVCC-----KAKGPFVEADC 124
                + ++ I+ +            +P   +  +A  +I+VC      K KG +++ DC
Sbjct: 51  -----ETKKKIAEI------------HPHAQMSAEAPVVILVCGDPTLEKCKGYWIQ-DC 92

Query: 125 WLAAENLMLAATAEGLGTCCIGFAVGILNMPDVKAELGIPEGGAAVAPIIVGFPRE 180
             A ENL+L AT  GLG    G       +   +  LGIPE     A + VG+P E
Sbjct: 93  SAAVENLLLRATELGLGAVWCGVYPREERVKAFRELLGIPEHVVPFALVPVGYPAE 148