BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0022.p (248 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO2977 [G] COG0837 Glucokinase Ype Yersinia pestis 165 7e-41 NMB1390 [G] COG0837 Glucokinase Nme Neisseria meningitidis MC58 159 6e-39 NMA1607 [G] COG0837 Glucokinase NmA Neisseria meningitidis Z2491 159 6e-39 CC2054 Non COG 159 6e-39 STM2403 [G] COG0837 Glucokinase Sty Salmonella typhimurium LT2 159 8e-39 >YPO2977 [G] COG0837 Glucokinase Ype Yersinia pestis Length = 323 Score = 165 bits (418), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 93/231 (40%), Positives = 121/231 (52%), Gaps = 2/231 (0%) Query: 7 FQDRFGFRTVHLLNDFEALAWSLPALQASDLRAMGTQRAAAAAPMLVIGPGTGFGAACFF 66 Q G + ++NDF A++ ++P L A D+ G + P+ V G GTG G A Sbjct: 86 MQQNLGLDHLEVINDFTAVSMAIPVLPAQDVLQFGGTQPQPGKPVAVYGAGTGLGVAHLV 145 Query: 67 P--SAAMVAVTEAGHATLPATSEREEQIIGQLRQRFGHVSVERVLSGSGLVNLYQALAAI 124 + E GH SE E+QI+ LRQ GHVS ERVLSG GLVNLY+A+ Sbjct: 146 NVDRRWISLAGEGGHVDFAPNSEEEDQILAVLRQELGHVSAERVLSGPGLVNLYRAIVIS 205 Query: 125 DGVAVPDRDPAAITQAALEKHCRISVAALDTFCAMLGAVAGDLALTLCARGGVYISGGIV 184 D P IT AL C AL FC ++G G+LAL L GGVYI+GGIV Sbjct: 206 DARLPEKLAPKDITARALADSCTDCRRALSLFCVIMGRFGGNLALNLSTFGGVYIAGGIV 265 Query: 185 PRFADRFVASRFRMQFECKGRYESYLRRIPTSLILDPDRSFIGLKAFCERS 235 PRF + F AS FR FE KGR++ +L+ IP +I P +G A+ + Sbjct: 266 PRFMEFFKASGFRAAFEDKGRFKDFLQDIPVYMITHPQPGLLGAGAYLRQK 316 >NMB1390 [G] COG0837 Glucokinase Nme Neisseria meningitidis MC58 Length = 328 Score = 159 bits (402), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 95/211 (45%), Positives = 123/211 (58%), Gaps = 2/211 (0%) Query: 11 FGFRTVHLLNDFEALAWSLPALQASDLRAMGTQRAAAAAPMLVIGPGTGFGAACFFPS-A 69 G T+ LLNDF A A ++ + DL +G Q+ AP VIGPGTG G + S A Sbjct: 98 LGLDTLILLNDFTAQALAVTQTSSKDLMQVGGQKPVEFAPKAVIGPGTGLGVSGLVHSHA 157 Query: 70 AMVAVT-EAGHATLPATSEREEQIIGQLRQRFGHVSVERVLSGSGLVNLYQALAAIDGVA 128 VA+ E GH + P + E I + ++GHVS ER LSG+GL +Y+ALAA Sbjct: 158 GWVALAGEGGHTSFPPFDDMEVLIWQYAKNKYGHVSAERFLSGAGLSLVYEALAAKQKAK 217 Query: 129 VPDRDPAAITQAALEKHCRISVAALDTFCAMLGAVAGDLALTLCARGGVYISGGIVPRFA 188 P+ IT+ AL + LD FCAMLG VA +LALTL ARGGVY+ GGI+PR Sbjct: 218 PAKLMPSEITEKALSGASPLCRQTLDIFCAMLGTVASNLALTLGARGGVYLCGGIIPRVL 277 Query: 189 DRFVASRFRMQFECKGRYESYLRRIPTSLIL 219 + F S FR +FE KGR+E+YL IP ++L Sbjct: 278 EYFKTSPFRSRFENKGRFEAYLAAIPVYVVL 308 >NMA1607 [G] COG0837 Glucokinase NmA Neisseria meningitidis Z2491 Length = 328 Score = 159 bits (402), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 95/211 (45%), Positives = 123/211 (58%), Gaps = 2/211 (0%) Query: 11 FGFRTVHLLNDFEALAWSLPALQASDLRAMGTQRAAAAAPMLVIGPGTGFGAACFFPS-A 69 G T+ LLNDF A A ++ + DL +G Q+ AP VIGPGTG G + S A Sbjct: 98 LGLDTLILLNDFTAQALAVTQTSSKDLMQVGGQKPVEFAPKAVIGPGTGLGVSGLVHSHA 157 Query: 70 AMVAVT-EAGHATLPATSEREEQIIGQLRQRFGHVSVERVLSGSGLVNLYQALAAIDGVA 128 VA+ E GH + P + E I + ++GHVS ER LSG+GL +Y+ALAA Sbjct: 158 GWVALAGEGGHTSFPPFDDMEVLIWQYAKNKYGHVSAERFLSGAGLSLVYEALAAKQKAK 217 Query: 129 VPDRDPAAITQAALEKHCRISVAALDTFCAMLGAVAGDLALTLCARGGVYISGGIVPRFA 188 P+ IT+ AL + LD FCAMLG VA +LALTL ARGGVY+ GGI+PR Sbjct: 218 PAKLMPSEITEKALSGASPLCRQTLDIFCAMLGTVASNLALTLGARGGVYLCGGIIPRVL 277 Query: 189 DRFVASRFRMQFECKGRYESYLRRIPTSLIL 219 + F S FR +FE KGR+E+YL IP ++L Sbjct: 278 EYFKTSPFRSRFENKGRFEAYLAAIPVYVVL 308 >CC2054 Non COG Length = 331 Score = 159 bits (401), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 92/220 (41%), Positives = 126/220 (57%), Gaps = 5/220 (2%) Query: 12 GFRTVHLLNDFEALAWSLPALQASDLRAMGTQRAAAAAPMLVIGPGTGFGAACFF--PSA 69 GFR L+NDF A A + P + DLR +G + + ++GPGTGFG A Sbjct: 99 GFRNAKLINDFTAQALAAPRVGPKDLRQIGELPTSGEGDLAILGPGTGFGVAGLVRRHGQ 158 Query: 70 AMVAVTEAGHATLPATSEREEQIIGQLRQRF--GHVSVERVLSGSGLVNLYQALAAIDGV 127 + TE GH + E +++ L +R G VSVER+LSG G+ +L+ LAA +G Sbjct: 159 EIPLATEGGHVAFAPVDDVEIEVLRALTRRLDGGRVSVERILSGPGMEDLHVDLAAAEGR 218 Query: 128 AVPDRDPAAITQAALEKHCRISVAALDTFCAMLGAVAGDLALTLCARGGVYISGGIVPRF 187 V IT+ A+E C S+A ++ FCA+LG+ AGD+ALTL ARGGV+I+GGI PR Sbjct: 219 GVEALTAKQITERAVEG-CADSLATVNRFCAILGSTAGDIALTLGARGGVFIAGGIAPRI 277 Query: 188 ADRFVASRFRMQFECKGRYESYLRRIPTSLILDPDRSFIG 227 D S FR +F+ KGR + R IPT +IL P + IG Sbjct: 278 IDILEKSPFRERFDSKGRLSGFTRSIPTHVILHPHTALIG 317 >STM2403 [G] COG0837 Glucokinase Sty Salmonella typhimurium LT2 Length = 321 Score = 159 bits (401), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 91/232 (39%), Positives = 121/232 (52%), Gaps = 2/232 (0%) Query: 6 DFQDRFGFRTVHLLNDFEALAWSLPALQASDLRAMGTQRAAAAAPMLVIGPGTGFGAA-- 63 + + GF + ++NDF A++ ++P L+ L G P+ V G GTG G A Sbjct: 85 EMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGGEPVDGKPIAVYGAGTGLGVAHL 144 Query: 64 CFFPSAAMVAVTEAGHATLPATSEREEQIIGQLRQRFGHVSVERVLSGSGLVNLYQALAA 123 + E GH SE E I+ LR GHVS ERVLSG GLVNLY+A+ Sbjct: 145 VHVDKRWISLPGEGGHVDFAPNSEEEAMILEILRAEIGHVSAERVLSGPGLVNLYRAIVK 204 Query: 124 IDGVAVPDRDPAAITQAALEKHCRISVAALDTFCAMLGAVAGDLALTLCARGGVYISGGI 183 D + P IT+ AL C AL FC ++G GDLALT+ GGVYI+GGI Sbjct: 205 SDNRLPENLRPKDITERALADSCIDCRRALSLFCVIMGRFGGDLALTMGTFGGVYIAGGI 264 Query: 184 VPRFADRFVASRFRMQFECKGRYESYLRRIPTSLILDPDRSFIGLKAFCERS 235 VPRF + F AS FR FE KGR++ Y+ IP LI+ + +G A ++ Sbjct: 265 VPRFLEFFKASGFRGGFEDKGRFKDYVHGIPVYLIVHDNPGLLGSGAHLRQT 316