BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0031.p (226 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr0922 [H] COG0302 GTP cyclohydrolase I Mlo Mesorhizobium loti 256 2e-68 BMEI0910 [H] COG0302 GTP cyclohydrolase I Bme Brucella melitensis 249 4e-66 CC0459 [H] COG0302 GTP cyclohydrolase I Ccr Caulobacter vibrioides 234 1e-61 AGc3211 [H] COG0302 GTP cyclohydrolase I Atu Agrobacterium tumef... 233 3e-61 SMc01005 [H] COG0302 GTP cyclohydrolase I Sme Sinorhizobium meli... 224 8e-59 >mlr0922 [H] COG0302 GTP cyclohydrolase I Mlo Mesorhizobium loti Length = 197 Score = 256 bits (655), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 117/187 (62%), Positives = 146/187 (78%) Query: 37 RPSRAEAEDAVKTLLAYIGENTGREGLLDTPRRVVEAYDELYQGYHQCPAEVLNRTFGET 96 RPS AE E AV+TLL + G+N REGL+DTP+RV +A+ E++ GY CPAE L RTF E Sbjct: 8 RPSEAEVEAAVRTLLRWTGDNPDREGLIDTPKRVAKAFREMFGGYDMCPAEELGRTFEEV 67 Query: 97 AGYDDFVLVRDIEFTSQCEHHMMPFYGKAHIAYTPVERVVGLSKLARLTDIFARRLQTQE 156 AGYDD V+V+DI F S CEHHM+P GKAH+ Y P +VVGLSK+AR+ DIFA RLQTQE Sbjct: 68 AGYDDLVIVKDIHFHSHCEHHMVPIIGKAHVGYLPDGKVVGLSKIARVVDIFAHRLQTQE 127 Query: 157 HLTAQVAAAIDEVLKPRGVAVLIEAEHTCMSVRGVAKHGASTFTSRFTGMFRDNPAEQQR 216 LTAQ+A I +VL PRGVAV+IEAEH CM++RG+ K G++T TS FTG+F+D P EQ R Sbjct: 128 ALTAQIAGVIQDVLNPRGVAVMIEAEHMCMAMRGIRKQGSTTLTSTFTGVFKDTPEEQVR 187 Query: 217 FLSLVRG 223 F+++VRG Sbjct: 188 FVTMVRG 194 >BMEI0910 [H] COG0302 GTP cyclohydrolase I Bme Brucella melitensis Length = 213 Score = 249 bits (635), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 116/194 (59%), Positives = 148/194 (76%) Query: 29 AAVRADQPRPSRAEAEDAVKTLLAYIGENTGREGLLDTPRRVVEAYDELYQGYHQCPAEV 88 A+V +P +AEAE AV+TLL + GE+ REGLL+TP+RV +AY EL+ GY + P EV Sbjct: 19 ASVTRIHKKPGKAEAEAAVRTLLLWAGEDPDREGLLETPKRVAKAYQELFGGYSESPEEV 78 Query: 89 LNRTFGETAGYDDFVLVRDIEFTSQCEHHMMPFYGKAHIAYTPVERVVGLSKLARLTDIF 148 L TF E AGYDD VLV+DI F S CEHHM+P GKAH+AY P RVVGLSK+AR+ DIF Sbjct: 79 LGTTFEEVAGYDDMVLVKDISFFSHCEHHMVPIIGKAHVAYLPEGRVVGLSKIARVVDIF 138 Query: 149 ARRLQTQEHLTAQVAAAIDEVLKPRGVAVLIEAEHTCMSVRGVAKHGASTFTSRFTGMFR 208 ARRLQTQE +TAQ+A +I +LKPRGVAV+IEAEH CM++R + K G+ST T+ FTG F+ Sbjct: 139 ARRLQTQESITAQIADSIQRILKPRGVAVMIEAEHMCMAMRSIRKQGSSTITTTFTGDFK 198 Query: 209 DNPAEQQRFLSLVR 222 + +Q RF++L+R Sbjct: 199 EKADQQVRFMTLIR 212 >CC0459 [H] COG0302 GTP cyclohydrolase I Ccr Caulobacter vibrioides Length = 212 Score = 234 bits (596), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 111/186 (59%), Positives = 140/186 (75%) Query: 37 RPSRAEAEDAVKTLLAYIGENTGREGLLDTPRRVVEAYDELYQGYHQCPAEVLNRTFGET 96 RPS+ EA AV+TLLA+ G+N REGL+DTP+RVVEA+DE + GYH PA+ L+RTF + Sbjct: 26 RPSKDEAMAAVRTLLAWAGDNPEREGLIDTPKRVVEAFDEWFAGYHGDPAKELSRTFEDV 85 Query: 97 AGYDDFVLVRDIEFTSQCEHHMMPFYGKAHIAYTPVERVVGLSKLARLTDIFARRLQTQE 156 GYDD V++R I+ S CEHHM PF GKA IAY P +VVGLSKLARL +IFA+RLQTQE Sbjct: 86 QGYDDMVMLRGIDVQSHCEHHMAPFLGKAWIAYMPTGKVVGLSKLARLVEIFAKRLQTQE 145 Query: 157 HLTAQVAAAIDEVLKPRGVAVLIEAEHTCMSVRGVAKHGASTFTSRFTGMFRDNPAEQQR 216 +T Q+A AI++ L GVAVLI+AEH CMS RGV H ST T++F G+F+ + QQR Sbjct: 146 TMTMQIADAIEDHLSAAGVAVLIDAEHQCMSTRGVHHHDVSTITTQFRGVFKTDKVLQQR 205 Query: 217 FLSLVR 222 F+ LV+ Sbjct: 206 FMDLVK 211 >AGc3211 [H] COG0302 GTP cyclohydrolase I Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 208 Score = 233 bits (594), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 129/223 (57%), Positives = 163/223 (73%), Gaps = 18/223 (8%) Query: 1 MDALIKSIRPNKP-ADAKPGELDPSEFMTAAVRADQPRPSRAEAEDAVKTLLAYIGENTG 59 MDA++K N P A AKP D +E RPS+AEAE+AV+ LL + GEN Sbjct: 1 MDAIVK----NFPGAGAKP---DVAE----------ARPSQAEAEEAVRVLLRWAGENPA 43 Query: 60 REGLLDTPRRVVEAYDELYQGYHQCPAEVLNRTFGETAGYDDFVLVRDIEFTSQCEHHMM 119 REGLLDTP+RV +AY EL+ GY +VL TF E GYDD VLVRDI F S CEHHM+ Sbjct: 44 REGLLDTPKRVAKAYRELFAGYELNVQDVLGTTFEEVGGYDDVVLVRDIPFFSHCEHHMV 103 Query: 120 PFYGKAHIAYTPVERVVGLSKLARLTDIFARRLQTQEHLTAQVAAAIDEVLKPRGVAVLI 179 P GKAH+AY P RV+GLSK+AR+ +IF RRLQTQE++TAQ+A +I+E LKPRGVAV+I Sbjct: 104 PIVGKAHVAYLPAGRVLGLSKIARVVEIFGRRLQTQENMTAQIARSIEETLKPRGVAVMI 163 Query: 180 EAEHTCMSVRGVAKHGASTFTSRFTGMFRDNPAEQQRFLSLVR 222 +AEH CMS+RGV K G++T T+ FTG F+++PAEQ RF+++VR Sbjct: 164 DAEHMCMSMRGVNKQGSTTLTTSFTGTFKNDPAEQVRFMTMVR 206 >SMc01005 [H] COG0302 GTP cyclohydrolase I Sme Sinorhizobium meliloti Length = 204 Score = 224 bits (572), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 115/190 (60%), Positives = 145/190 (76%) Query: 34 DQPRPSRAEAEDAVKTLLAYIGENTGREGLLDTPRRVVEAYDELYQGYHQCPAEVLNRTF 93 D RP++ EAE+AV+ LL + GE+ REGL DTP RV +AY E++ GY +VL RTF Sbjct: 13 DTGRPTQKEAEEAVRVLLRWAGEDPAREGLKDTPSRVAKAYREIFGGYDLVAEDVLGRTF 72 Query: 94 GETAGYDDFVLVRDIEFTSQCEHHMMPFYGKAHIAYTPVERVVGLSKLARLTDIFARRLQ 153 E +GYDD VL +DI F S CEHHM+P GKAHIAY P RV+GLSK+AR+ DI+ARRLQ Sbjct: 73 EEVSGYDDIVLEKDIPFYSHCEHHMVPIIGKAHIAYLPNGRVLGLSKIARVVDIYARRLQ 132 Query: 154 TQEHLTAQVAAAIDEVLKPRGVAVLIEAEHTCMSVRGVAKHGASTFTSRFTGMFRDNPAE 213 TQE +TAQ+A AIDE L PRGVAV+IEAEH CM++RG+ K GA+T T+ FTG F+ PAE Sbjct: 133 TQEAMTAQIAKAIDETLMPRGVAVMIEAEHLCMAMRGIKKQGATTLTTTFTGAFKSEPAE 192 Query: 214 QQRFLSLVRG 223 Q RF++++RG Sbjct: 193 QVRFMTMLRG 202