BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0138.p (265 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4089 [IQR] COG1028 Dehydrogenases with different specificities... 209 4e-54 mll8564 [IQR] COG1028 Dehydrogenases with different specificitie... 169 5e-42 AGpA355 [IQR] COG1028 Dehydrogenases with different specificitie... 151 2e-36 SMc00268 [IQR] COG1028 Dehydrogenases with different specificiti... 145 1e-34 mll6717 [IQR] COG1028 Dehydrogenases with different specificitie... 142 9e-34 >PA4089 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Pae Pseudomonas aeruginosa Length = 253 Score = 209 bits (533), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 121/250 (48%), Positives = 158/250 (63%), Gaps = 4/250 (1%) Query: 8 LDGRVVIVTGGGRGIGAAIVRRLAEAGATVVIANRTLDVAEALARELVADGRSAHCIPFD 67 L+ RV +VTG G+GIG AI A GA V++A RT +A+ + G +A + D Sbjct: 4 LENRVALVTGAGQGIGRAIAECFAAEGARVLLATRTASRGQAVLEAIRLGGGTAELLAVD 63 Query: 68 RLDRGGLRAMVDRVAAQYGRLDIVVHNAGGCPWSSIEELDETKLEDTLALNLSASIWLAQ 127 + R V ++G+LDI++HNA P ++ ELDE LE TLA+NL + L Q Sbjct: 64 LSEYDAARRAVSATLERFGQLDILLHNAAAFPQCALAELDEGTLERTLAVNLKSCFRLTQ 123 Query: 128 AAIPHMRAVRFGRILVTSSVSA-RVAMGGGAHYSAAKAGVNAFIRGAAFELARDGITVNG 186 AA+P +R GR+LVTSSV+ R A+ G +HY+A+KAGVN FIR AA ELA DGITVNG Sbjct: 124 AALPALRRSVAGRVLVTSSVTGPRTAIPGLSHYAASKAGVNGFIRAAALELAGDGITVNG 183 Query: 187 VEAGFIEKPGRGTMSAAENRAKLERFIPMGHMGSADDIACAMLYLASSEAKYVTGQTIVV 246 VE G + P G++ A A L IP+G +G DIA AML+LAS EA Y+TGQT+VV Sbjct: 184 VEPGLVATPALGSLGDA---AALAAHIPLGRVGQPLDIAHAMLFLASDEASYITGQTLVV 240 Query: 247 DGGSTLPETG 256 DGG+ LPE G Sbjct: 241 DGGALLPENG 250 >mll8564 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 256 Score = 169 bits (429), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 106/251 (42%), Positives = 138/251 (54%), Gaps = 12/251 (4%) Query: 8 LDGRVVIVTGGGRGIGAAIVRRLAEAGATVVIANRTLDVAEALARELVADGRSAHCIPFD 67 L +V ++ G RGIG I R AE GA +V+A+ + +A A EL +PF Sbjct: 5 LKDKVALIIGSARGIGKGIALRFAEEGARLVLADSEAEAGQATADEL--------GVPFI 56 Query: 68 RLDRGGLR---AMVDRVAAQYGRLDIVVHNAGGCPWSSIEELDETKLEDTLALNLSASIW 124 D +R A V ++GRLDI+V NAG PW IE + +A+NL + Sbjct: 57 GTDISQMRDAEASVALALKRHGRLDIIVQNAGIYPWQLIENTSTDDWDRVMAVNLRGTFN 116 Query: 125 LAQAAIPHMRAVRFGRILVTSSVSA-RVAMGGGAHYSAAKAGVNAFIRGAAFELARDGIT 183 +AA+ M+A R GR+L TSS++ V G HYSA KAG+N FIR AA E + GIT Sbjct: 117 ATRAALVPMKAQRSGRMLYTSSITGPHVTSPGHGHYSATKAGINGFIRAAALEFSGYGIT 176 Query: 184 VNGVEAGFIEKPGRGTMSAAENRAKLERFIPMGHMGSADDIACAMLYLASSEAKYVTGQT 243 VNGVE G I A +E IP+G +GS D+A A L+LAS +A Y+TG T Sbjct: 177 VNGVEPGNILTEAIQQHRGAAYIKNMEDSIPLGRLGSPRDVANAFLFLASDDAGYITGTT 236 Query: 244 IVVDGGSTLPE 254 IVVDGG LPE Sbjct: 237 IVVDGGQLLPE 247 >AGpA355 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 257 Score = 151 bits (381), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 96/255 (37%), Positives = 141/255 (55%), Gaps = 5/255 (1%) Query: 7 NLDGRVVIVTGGGRGIGAAIVRRLAEAGATVVIANRTLDVAEALARELVADGRSAHCIPF 66 +L G+ VIVTG RGIG I R EAG V++ +R+ A+ +A E+ +G Sbjct: 4 SLQGKTVIVTGASRGIGKGIALRFGEAGLNVLVVSRSQVDADRVASEIGVNGSGFAA--- 60 Query: 67 DRLDRGGLRAMVDRVAAQYGRLDIVVHNAGGCPWSSIEELDETKLEDTLALNLSASIWLA 126 D G +AMVD +YG ++++ NAG P + + E+ + ++ NL ++ Sbjct: 61 DVSTEEGCKAMVDAAVTRYGGVNVLCANAGIFPAAKLGEMSAADFDHVISTNLKSTFLSV 120 Query: 127 QAAIPHMRAVRFGRILVTSSVSARVA-MGGGAHYSAAKAGVNAFIRGAAFELARDGITVN 185 A +P M + GRI++TSS++ + G +HY A+KAG F+R AA ELA ITVN Sbjct: 121 SAVLPAMTSAGAGRIIITSSITGPITGYPGWSHYGASKAGQLGFMRTAAIELAPKNITVN 180 Query: 186 GVEAGFIEKPGRGTMSAAENRAKLERFIPMGHMGSADDIACAMLYLASSEAKYVTGQTIV 245 V G I G + + A +E +P+ +G DIA A L+ AS EA Y+TGQ+IV Sbjct: 181 AVMPGNIMTEGL-EGNGPDYIATMEASVPLRRLGMPADIANAALFFASEEAAYITGQSIV 239 Query: 246 VDGGSTLPETGFAVE 260 VDGG LPE+ A+E Sbjct: 240 VDGGQILPESLGALE 254 >SMc00268 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 252 Score = 145 bits (365), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 96/249 (38%), Positives = 137/249 (55%), Gaps = 7/249 (2%) Query: 8 LDGRVVIVTGGG--RGIGAAIVRRLAEAGATVVIANRTLDVAEALARELVADGRSAHCIP 65 L+G ++TG RG+G A R AE GATV I + A A L C Sbjct: 6 LEGNFAVITGAASRRGLGKATARLFAEHGATVAILDLDEADAREAAASLGPRHVGMAC-- 63 Query: 66 FDRLDRGGLRAMVDRVAAQYGRLDIVVHNAGGCPWSSIEELDETKLEDTLALNLSASIWL 125 + D +R ++D + +Q+GR+DI+V+NAG I E+ + L +NL +++ Sbjct: 64 -NVTDLASVRTVMDALVSQWGRIDILVNNAGITQPLKIMEIAPENYDAVLDVNLRGTLYC 122 Query: 126 AQAAIPHMRAVRFGRILVTSSVSARVAMG--GGAHYSAAKAGVNAFIRGAAFELARDGIT 183 +QA IPHMR+ + G+I+ SSVSA+ G GG HYSAAKAGV + A ELA D + Sbjct: 123 SQAVIPHMRSRKQGKIVNLSSVSAQRGGGIFGGPHYSAAKAGVLGLTKAMARELAPDNVR 182 Query: 184 VNGVEAGFIEKPGRGTMSAAENRAKLERFIPMGHMGSADDIACAMLYLASSEAKYVTGQT 243 VN + GFI G + E +++ IPMG G+ADD+A L+LAS + YVTG Sbjct: 183 VNAICPGFIATDITGGLLTPEKLEEIKAGIPMGRPGTADDVAGCALFLASDLSAYVTGSE 242 Query: 244 IVVDGGSTL 252 + V+GGS + Sbjct: 243 VDVNGGSLI 251 >mll6717 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 254 Score = 142 bits (357), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 99/251 (39%), Positives = 143/251 (56%), Gaps = 7/251 (2%) Query: 7 NLDGRVVIVTGGGRGIGAAIVRRLAEAGATVVIANRTLDVAEALARELVADGRSAHCIPF 66 +L GR V+VTGG +GIG I R A +GA V I R D AEA A E+ G A + Sbjct: 4 SLKGRSVVVTGGSKGIGKGIARVFALSGAKVAIVARHPDQAEAAAAEI---GHGAFGVVG 60 Query: 67 DRLDRGGLRAMVDRVAAQYGRLDIVVHNAGGCPWSSIEELDETKLEDTLALNLSASIWLA 126 D + + + VAA+ G +D++ NAG P + +E++ + ++ + NL + Sbjct: 61 DVTSLASIESALAVVAARNGSIDVLCANAGIFPQARLEDMTSQQWDEVVDTNLKGTFHAV 120 Query: 127 QAAIPHMRAVRFGRILVTSSVSARVA-MGGGAHYSAAKAGVNAFIRGAAFELARDGITVN 185 +AA+P+++ GRI++TSS++ + G +HY A KAG F+R A ELA+ GITVN Sbjct: 121 KAAVPYLKTSNQGRIVLTSSITGPITGFPGWSHYGATKAGQLGFMRTACIELAKYGITVN 180 Query: 186 GVEAGFIEKPGRGTMSAAENRAK-LERFIPMGHMGSADDIACAMLYLASSEAKYVTGQTI 244 V G I G + E+ K + IP+ +G+ +DI A LY AS EA YVTGQTI Sbjct: 181 AVMPGNIVT--EGLVGLGEDYQKTMAASIPLKRLGTVEDIGYAALYFASKEAGYVTGQTI 238 Query: 245 VVDGGSTLPET 255 +VDGG LPE+ Sbjct: 239 IVDGGQILPES 249