BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0057.p (1082 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr1377 Non COG 804 0.0 AGc5085 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 778 0.0 BMEI0695 [H] COG1429 Cobalamin biosynthesis protein CobN and rel... 451 e-126 SMc04303 [H] COG1429 Cobalamin biosynthesis protein CobN and rel... 432 e-120 alr1689 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 419 e-116 >mlr1377 Non COG Length = 1126 Score = 804 bits (2077), Expect = 0.0, Method: Compositional matrix adjust. Identities = 492/1112 (44%), Positives = 668/1112 (60%), Gaps = 42/1112 (3%) Query: 1 MHVVFRESRGLEETATPRDLGQDPADLVVLSFSDSDLAAFAAGWRRGRAALPSLRLANLA 60 MH++ S L++ A P DL Q PAD+V LSF+DSDLA AA W+ + LPS+RLA L Sbjct: 1 MHILTTTSASLDDLAEPVDLRQTPADIVALSFTDSDLAGLAAAWKADASRLPSMRLAALR 60 Query: 61 ELRHPLSVDTYIERTLSHARGILVRLIGGEPYWSYGLAAVHRLAKERGIALVVLPADGRD 120 +LRHP+SVD +++ A+ ILVR++GG +W YG + A+ERGI L +LP + D Sbjct: 61 DLRHPMSVDLWVDSVARRAKIILVRILGGYDWWRYGCDQLASTARERGIQLALLPGESHD 120 Query: 121 -DLRLDGFSTLPVSTLRRLKVLCDKGGPVAAQAVIAQLALASGLYAGPVVGEIDLPEIGV 179 DLRL STLP L L +GGP A++ +LA +G A VV + +P+ G Sbjct: 121 EDLRLIEASTLPRQELDALLGYFREGGPANMGALVQRLARLAGQDAA-VVEPVAVPKAGY 179 Query: 180 YELRRGAVAALPASDGRPLVLVTFYRSYLAAGDTAPVDALIEALREKGFDAHGVFVTSLK 239 Y+ RG V LP + + FYRS L A D AP+D L +ALR++G +FV+SLK Sbjct: 180 YQPGRGVVP-LPLEREGKVAPILFYRSMLLAADVAPIDVLFDALRQRGMTPVPIFVSSLK 238 Query: 240 AAGVADWLRAQFAHCPPAAIVNATAFSAAGDDGT-TPFDAALCPVFQVALSTARREDWAL 298 + A PAAI+ ATAF++ + G T FD A PVFQV ++T RR+ W Sbjct: 239 DPTSLAFAETALATLRPAAIITATAFASGAEPGVETLFDRAGVPVFQVIVATTRRDVWEN 298 Query: 299 SLRGLSPGDLAMHVVLPEVDGRLFAGVVSFKSPGERDPELQFAHLAHRPDAERVAAIAAR 358 + RGL+P DLAMHVVLPE+DGR+ AG +SFK + DP L A+RP+ +RVA +A R Sbjct: 299 NQRGLAPADLAMHVVLPELDGRILAGAISFKGESDVDPALGHRAFANRPEPDRVAQVADR 358 Query: 359 VAAWHRLASKPAQKKQLALVLSNYPGRPHQIAHAVGLDALASVEALLADLAGAGFDLAPV 418 VAA+ +L P +++LA+++ +YP P + +AVGLD +SV A+L DL G+ + + Sbjct: 359 VAAFIKLQETPRAERKLAVLIPDYPSAPGRTGYAVGLDVPSSVLAMLHDLKEQGYGVEGI 418 Query: 419 ----RSLGDVLLHRRLTWDVAEYRTALSSLPLQLQDDLARAWGTPEDDPECRDGA----- 469 R+L D+L + +Y LP ++ + AWG E++ R+G Sbjct: 419 PQSPRALLDLLERGGDGLGLEDYVGLSKELPAEVMTAVEAAWGKAEEETGLREGGASHKP 478 Query: 470 -------FHFSAVQSGKSIIAVQPERGEVTHRDADYHDLSRTPRHAYVAFYLWLRQQ-GI 521 F F A G +A+ P+RG R ADYHD + PRHA +AF LWLR+ G+ Sbjct: 479 SLSSKKHFPFRATTFGNITVALAPDRGRSADRRADYHDPTLAPRHALLAFGLWLRKSLGV 538 Query: 522 DAVVHIGAHGTLEWLPGKSVALSSACWPEALTGDLPVVYPFIVNDPGEAAQAKRRIGAVT 581 A++H+GAHGTLEWLPGK+VALS C+PE +TG LPV+YPFIV++PGEAAQAKRRI AVT Sbjct: 539 HALIHVGAHGTLEWLPGKTVALSQTCFPEIVTGALPVIYPFIVSNPGEAAQAKRRIAAVT 598 Query: 582 IGHLPPPLAQAAVPEGLRSLERLLDEYSTADGLDPARRQRLIAAIRDEARIAGLEDDLSL 641 +GHLPPPL A + E LERL+DEY+ ADGLD RR RL I D A+ GL + + Sbjct: 599 LGHLPPPLTGAGLDENQHKLERLVDEYAQADGLDRRRRDRLARLIVDTAQKTGLAAEAGV 658 Query: 642 AASVSAAEAIPQIDRFVCDLKESQFGDGLHIFGQGACGEAERAALRDALA---------- 691 A + + EA+ +ID ++CDLK+ DGLHI+G+ E++ A R + Sbjct: 659 ARTDAPDEALRRIDAWLCDLKDFAIKDGLHIYGRAPDDESD-AMRRQSAEAEKAALLAAL 717 Query: 692 -GRRVAPGPSGSPWRGRGDVLPTGRNLFAVDPRAVPTPSAHAQGVKLAEELLRRHLQDHG 750 GR V GP+G+P RGR DVLPTGRNLF DPR +PTP+A+ G AEE++R +LQ HG Sbjct: 718 DGRHVKAGPAGAPARGRSDVLPTGRNLFTSDPRTMPTPTAYDLGKAAAEEVVRGYLQSHG 777 Query: 751 DWPKGLVVDLWGSSTMRTAGEDFAMALHLAGIAPRWDHGSGRVSGYDIIAPAELGRPRID 810 DWP+ LV+DLWGS+++RT GE+ A L L G P+WD +GR++G +++ PA LGRPR+D Sbjct: 778 DWPRSLVIDLWGSASLRTGGEEIAQGLALMGCRPQWDAATGRITGIEVLPPATLGRPRVD 837 Query: 811 VTLRVSGLFRDVFSGLAQLFEAAAEALSERCDEADENPYRERIS-------RVFGPRPGY 863 VT R+SGLFRD+F L +AAA A++ R +E ENP R R+FG PG Sbjct: 838 VTWRISGLFRDMFPTQIALIDAAANAVAARDEEDSENPLAARTRADGKISPRIFGTSPGT 897 Query: 864 YGVGIASMPDVFTEAAREAAGEAWLSASSWAL-ASDGEMRPDRAGIEARLAAADSFVHTQ 922 YG G+ + AARE G A+L A+S A + GE E R+A AD VHT Sbjct: 898 YGAGVEDLLSSGDWAAREEIGRAYLDATSHAYGGAGGEGISAPGAFETRIAEADLLVHTG 957 Query: 923 DLPETDLLLAADYAAHEAGIAAAARRLGTKVPALYHLDATRPDRPHARALTEEISRVVRV 982 D P D+L + A G +AA LG + LD T P +P R+++E +SRVVR Sbjct: 958 DDPGRDILEGSADVAFIGGFSAALAALGRNADVIV-LDTTDPQKPKPRSVSEAVSRVVRA 1016 Query: 983 RAANPAWIAGMMRHGFRGAAEISATLEHMAAFAHLAGAVPPHLFDLYYDATLGNDEVRCF 1042 RA NP +I+G MRHG RGA+E + T++ + FA A+ L + +DA +G+ +VR F Sbjct: 1017 RAINPRFISGQMRHGPRGASEFAETVDRLVGFAETTHAISGALIEAVHDAYVGDADVRAF 1076 Query: 1043 MARENPAALAAIETCFSRLHEASLWQTRRNSI 1074 + RENPAA I F LW RNSI Sbjct: 1077 ILRENPAAAKVIAERFLSARRRGLWHPLRNSI 1108 >AGc5085 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1116 Score = 778 bits (2010), Expect = 0.0, Method: Compositional matrix adjust. Identities = 487/1109 (43%), Positives = 654/1109 (58%), Gaps = 35/1109 (3%) Query: 1 MHVVFRESRGLEETATPRDLGQDPADLVVLSFSDSDLAAFAAGWRRGRAALPSLRLANLA 60 MH++ S L++ P DL Q +D+VVLSFS SDLA W + LPSL ANL+ Sbjct: 1 MHILATTSSSLDDLIEPVDLNQPRSDVVVLSFSASDLAGLERAWGKAGETLPSLSAANLS 60 Query: 61 ELRHPLSVDTYIERTLSHARGILVRLIGGEPYWSYGLAAVHRLAKERGIALVVLPADGRD 120 ELRHP+SVD +IE+T HAR IL+R++GG W YG+ + LA+ RGI L++LP + + Sbjct: 61 ELRHPMSVDLWIEKTAEHARVILIRILGGAERWRYGVDQLAILARRRGIKLLLLPGECSE 120 Query: 121 -DLRLDGFSTLPVSTLRRLKVLCDKGGPVAAQAVIAQLALASGLYAGPVVGEIDLPEIGV 179 D +L+ ST+ L + +GG + A L++ +G P + LP+ G Sbjct: 121 RDEKLEAASTVDKPMLASVLSFFREGGRENMGRLAAGLSVLAGGGEWPDIKADPLPKAGF 180 Query: 180 YELRRGAVAALPASDGRP----LVLVTFYRSYLAAGDTAPVDALIEALREKGFDAHGVFV 235 Y G V A G P ++ + FYRS L A D APVDAL +AL +GF +FV Sbjct: 181 YRPDLGVVGQDEACAGFPAGASVLPILFYRSMLLAEDAAPVDALFQALSARGFAPLPIFV 240 Query: 236 TSLKAAGVADWLRAQFAHCPPAAIVNATAFSAAGDD-GTTPFDAALCPVFQVALSTARRE 294 + LK +L PAAI+ ATAF++ DD G T FD PVFQ ++T RR Sbjct: 241 SGLKDGEAIRFLETVLPALQPAAIIAATAFASHTDDRGETLFDRLGVPVFQAVMATTRRV 300 Query: 295 DWALSLRGLSPGDLAMHVVLPEVDGRLFAGVVSFKSPGERDPELQFAHLAHRPDAERVAA 354 W + RGL+P DLAMHVVLPE+DGR+ G +SFK D + ++ P+A+R+ Sbjct: 301 GWVENARGLNPSDLAMHVVLPELDGRILTGAISFKQ-ARTDGGVSLVNV---PEADRIEQ 356 Query: 355 IAARVAAWHRLASKPAQKKQLALVLSNYPGR-PHQIAHAVGLDALASVEALLADLAGAGF 413 +A R+AA+ RL S P + +++ +++ +YPG P + +AVGLD SV +L DLA AG+ Sbjct: 357 VANRIAAFLRLKSAPPRDRRIVILMPDYPGAAPGRTGYAVGLDVPQSVLEMLRDLAEAGY 416 Query: 414 DLAPV----RSLGDVLLHRRLTWDVAEYRTALSSLPLQLQDDLARAWGTPEDDPECRDGA 469 + + R+L D + + T D++ YR + L + WG E D DGA Sbjct: 417 AVEDIPETARALLDRIESQEATVDLSTYRDFFAGLTETASSSMNATWGAAEQDDAFADGA 476 Query: 470 FHFSAVQSGKSIIAVQPERGEVTHRDADYHDLSRTPRHAYVAFYLWLRQQ-GIDAVVHIG 528 FHF + G+ +A+ P+RG R DYHD + PRHA VAF W++ A+VH+G Sbjct: 477 FHFRVARFGQVFVALAPDRGRNEDRRVDYHDPALPPRHALVAFGAWMQSVVATHAIVHVG 536 Query: 529 AHGTLEWLPGKSVALSSACWPEALTGDLPVVYPFIVNDPGEAAQAKRRIGAVTIGHLPPP 588 AHGTLEWLPGK+VALS C+PE +TG LPVVYPFIV++PGEAA AKRRI AVTIGH+PP Sbjct: 537 AHGTLEWLPGKTVALSRDCFPEIVTGPLPVVYPFIVSNPGEAAVAKRRIAAVTIGHVPPV 596 Query: 589 LAQAAVPEGLRSLERLLDEYSTADGLDPARRQRLIAAIRDEARIAGLEDDLSLAASVSAA 648 L A + +LE+L+DEY+ ADGLD RR RL I ++A GL + + A A Sbjct: 597 LVNAGLSPEQLALEQLVDEYAQADGLDRRRRDRLAKLIVEKALETGLAAEAGVGAKDDAD 656 Query: 649 EAIPQIDRFVCDLKESQFGDGLHIFGQGACGEAERAALRDALA----------GRRVAPG 698 A+ +ID F+CDLK+ DG H+FG+ GEA+ L+ A A GR +APG Sbjct: 657 AALSRIDAFLCDLKDFAIKDGQHVFGRSPEGEADPLRLQSAKAEKAALLAALDGRHIAPG 716 Query: 699 PSGSPWRGRGDVLPTGRNLFAVDPRAVPTPSAHAQGVKLAEELLRRHLQDHGDWPKGLVV 758 PSG+P RGR DVLPTGRNL+A DPR +PTP+A G EE+LR HLQ HGDWPK LV Sbjct: 717 PSGAPARGRLDVLPTGRNLYAADPRTMPTPTAFDLGRMAGEEVLRHHLQSHGDWPKHLVF 776 Query: 759 DLWGSSTMRTAGEDFAMALHLAGIAPRWDHGSGRVSGYDIIAPAELGRPRIDVTLRVSGL 818 DLWGS+++R GED A ALHL G P D +GRV+G +++ PA LGRPR+DVT R+SGL Sbjct: 777 DLWGSASLRNGGEDVAQALHLMGARPIHDPATGRVTGIEVLPPASLGRPRVDVTFRISGL 836 Query: 819 FRDVFSGLAQLFEAAAEALSERCDEADENPYRERI-------SRVFGPRPGYYGVGIASM 871 FRD+F L L +AAA+A++ R + +NP E +R+FG PG YG GI Sbjct: 837 FRDMFPALIALLDAAAKAVARRDEAPGDNPLAEEAAALGHIPARIFGSAPGTYGAGIEEK 896 Query: 872 PDVFTEAAREAAGEAWLSASSWAL-ASDGEMRPDRAGIEARLAAADSFVHTQDLPETDLL 930 T RE G+A+L A++ A +DG + AG + AD VHT D P DLL Sbjct: 897 LASGTWDEREELGQAYLDAANHAFGGADGLEIFEDAGFTELVRRADLLVHTGDDPGRDLL 956 Query: 931 LAADYAAHEAGIAAAARRLGTKVPALYHLDATRPDRPHARALTEEISRVVRVRAANPAWI 990 + A G +AA LG + + LD T P RP AR++T+ ++RVVR RA NP +I Sbjct: 957 DGSSDVAFIGGFSAAKAVLG-GIADIVALDTTDPARPRARSMTQALTRVVRARAVNPRFI 1015 Query: 991 AGMMRHGFRGAAEISATLEHMAAFAHLAGAVPPHLFDLYYDATLGNDEVRCFMARENPAA 1050 AG MRHG RGAAE + T++ + FA V L + YDA GN+EVR F+ RENP A Sbjct: 1016 AGQMRHGPRGAAEFAETVDRLVGFAETTHVVSSSLIEALYDAYFGNEEVRDFILRENPKA 1075 Query: 1051 LAAIETCFSRLHEASLWQTRRNSIAAALQ 1079 + F LW +RRN++ A L+ Sbjct: 1076 AEVMAARFLSARRRGLWHSRRNAVDAELE 1104 >BMEI0695 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Bme Brucella melitensis Length = 1263 Score = 451 bits (1159), Expect = e-126, Method: Compositional matrix adjust. Identities = 276/710 (38%), Positives = 383/710 (53%), Gaps = 48/710 (6%) Query: 1 MHVVFRESRGLEETATPRDLGQDPADLVVLSFSDSDLAAFAAGWRRGRAALPSLRLANLA 60 MH++ + + + DLGQ P ++V LS +D++LA+ A R +PSLRLAN Sbjct: 1 MHLLLAQKGTISDGNEAVDLGQTPGEIVFLSAADTELASIAQAHRLA-PDMPSLRLANFL 59 Query: 61 ELRHPLSVDTYIERTLSHARGILVRLIGGEPYWSYGLAAVHRLAKERGIALVVLPADGRD 120 L HP+SVD Y+ERT HA+ I+VR+IGGE YW YGL A+H A G + VLP D + Sbjct: 60 GLTHPMSVDAYVERTARHAKLIVVRIIGGETYWPYGLEALHACAITHGAKMAVLPGDDKP 119 Query: 121 DLRLDGFSTLPVSTLRRLKVLCDKGGPVAAQAVIAQLALASGLYAGPVVGEIDLPEIGVY 180 D LD FST+P L + G +A Y ++ + PE Sbjct: 120 DHGLDRFSTIPAGERDDLWHYLIESGAANTHGFLA--------YCKALISGCEKPEAAAP 171 Query: 181 ELRRG------AVAALP------ASDGRPLVLVTFYRSYLAAGDTAPVDALIEALREKGF 228 L+ G AV++L A P+ + YR+ + +G T PVDALI AL+ +G Sbjct: 172 LLKAGLWWPGEAVSSLTSVQRHWADPAAPVAAIILYRALVQSGQTQPVDALIAALQARGL 231 Query: 229 DAHGVFVTSLK---AAGVADWLRAQFAHCPPAAIVNATAF---SAAGDDGTTPFDAALCP 282 + +FV+SLK +A V D L F CPP ++NAT F S + T D Sbjct: 232 NPLPIFVSSLKDPLSAAVVDGL---FEDCPPDIVLNATGFAISSPGAERKPTVLDKRGNM 288 Query: 283 VFQVALSTARREDWALSLRGLSPGDLAMHVVLPEVDGRLFAGVVSFKSPGERDPELQFAH 342 V QV S + W S +GL DLAM+V LPEVDGR+ + VSFKS + D ++ Sbjct: 289 VLQVIFSGTPKTVWEASQQGLLARDLAMNVALPEVDGRVLSRAVSFKSAQQFDASVEANI 348 Query: 343 LAHRPDAERVAAIAARVAAWHRLASKPAQKKQLALVLSNYPGRPHQIAHAVGLDALASVE 402 + H P +RVA +A A W RL KP ++++AL+L+NYP R ++ + VGLD A Sbjct: 349 VTHEPHPDRVAFVAELAANWVRLKRKPPAERRVALILANYPNRDGRLGNGVGLDTPAGTV 408 Query: 403 ALLADLAGAGFDLAPVRSLGDVLLHR---------------RLTWDVAEYRTALSSLPLQ 447 +L +A G+ + + + D L+ R T + +Y+ L L Sbjct: 409 EVLRAMAAEGYRVGEIPADSDALMRALMAGPTNAARDGREIRETISLNQYKALFGKLALT 468 Query: 448 LQDDLARAWGTPEDDPE-CRD-GAFHFSAVQSGKSIIAVQPERGEVTHRDADYHDLSRTP 505 +Q ++ WG PE+DP R+ AF ++ G++ + +QP RG YH L P Sbjct: 469 IQAEVEARWGAPENDPYFARELDAFALPLMRFGETFVGIQPARGYNIDPKETYHSLDLVP 528 Query: 506 RHAYVAFYLWLRQ-QGIDAVVHIGAHGTLEWLPGKSVALSSACWPEALTGDLPVVYPFIV 564 H Y+A+Y +LR G+DAVVH+G HG LEWLPGK++ALS C+PEA+ G +P +YPFIV Sbjct: 529 PHGYIAYYAYLRAVAGVDAVVHMGKHGNLEWLPGKALALSQNCYPEAVFGPMPHIYPFIV 588 Query: 565 NDPGEAAQAKRRIGAVTIGHLPPPLAQAAVPEGLRSLERLLDEYSTADGLDPARRQRLIA 624 NDPGE QAKRR AV I HL PPL +A L+ LE L+DEY A G+DP R RL A Sbjct: 589 NDPGEGTQAKRRASAVIIDHLTPPLTRAESYGPLKDLEALVDEYYEASGVDPRRLLRLKA 648 Query: 625 AIRDEARIAGLEDDLSLAASVSAAEAIPQIDRFVCDLKESQFGDGLHIFG 674 I D R GL+ D + A+ ++D ++CDLKE Q DGLH+FG Sbjct: 649 QILDLVRDIGLDRDAGIHDHDDEDMALQKLDAYLCDLKEMQIRDGLHVFG 698 Score = 352 bits (904), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 191/428 (44%), Positives = 251/428 (58%), Gaps = 22/428 (5%) Query: 677 ACGEAERAALRDALAGRRVAPGPSGSPWRGRGDVLPTGRNLFAVDPRAVPTPSAHAQGVK 736 +CG +E AL+GR V PGPSG+P RGR DVLPTGRN F+ D RAVPTP+A G K Sbjct: 822 SCGPSEIDGFLAALSGRFVPPGPSGAPTRGRPDVLPTGRNFFSTDSRAVPTPAAWELGKK 881 Query: 737 LAEELLRRHLQDHGDWPKGLVVDLWGSSTMRTAGEDFAMALHLAGIAPRWDHGSGRVSGY 796 AE L+ R+ QDHG+WP + WG+S MRT G+D A AL L G+ P WD S RV+GY Sbjct: 882 SAELLITRYTQDHGEWPTSFGLTAWGTSNMRTGGDDIAQALALIGVQPVWDMASRRVTGY 941 Query: 797 DIIAPAELGRPRIDVTLRVSGLFRDVFSGLAQLFEAAAEALSERCDEADENPYRERIS-- 854 +I+ PA+L RPR+DVTLR+SG FRD F LF+ A A+ ++ ++NP R+ Sbjct: 942 EIVPPAKLARPRVDVTLRISGFFRDAFPEQIALFDKAVRAVGALDEDVEDNPIAARMKAE 1001 Query: 855 --------------------RVFGPRPGYYGVGIASMPDVFTEAAREAAGEAWLSASSWA 894 RVFG +PG YG G+ ++ D A R EAWL +A Sbjct: 1002 QARLVAGGADPQTAERRAGYRVFGSKPGAYGAGLQALIDENGWAGRNDLAEAWLVWGGYA 1061 Query: 895 LASDGEMRPDRAGIEARLAAADSFVHTQDLPETDLLLAADYAAHEAGIAAAARRLGTKVP 954 + E + +R +E RL + + V QD E DLL + DY E G+AA L +P Sbjct: 1062 YGAGEEGQAERGLLEERLRSVQAVVQNQDNREHDLLDSDDYYQFEGGMAATVESLTGAMP 1121 Query: 955 ALYHLDATRPDRPHARALTEEISRVVRVRAANPAWIAGMMRHGFRGAAEISATLEHMAAF 1014 ++YH D +RP++P RAL EE+SRVVR RAANP WIAG+MRHG++GAAEI+AT++++ AF Sbjct: 1122 SVYHNDHSRPEKPVIRALEEELSRVVRGRAANPKWIAGVMRHGYKGAAEIAATVDYLFAF 1181 Query: 1015 AHLAGAVPPHLFDLYYDATLGNDEVRCFMARENPAALAAIETCFSRLHEASLWQTRRNSI 1074 A G V H F+ Y A + + V FMA +NPAALA + E W R NS Sbjct: 1182 AATTGKVGNHHFEAVYQAYIADRAVHDFMAEKNPAALAETAAKLNEAIERGFWTPRSNSA 1241 Query: 1075 AAALQEAS 1082 L+ S Sbjct: 1242 RFELENLS 1249 >SMc04303 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Sme Sinorhizobium meliloti Length = 1275 Score = 432 bits (1112), Expect = e-120, Method: Compositional matrix adjust. Identities = 274/710 (38%), Positives = 385/710 (54%), Gaps = 38/710 (5%) Query: 1 MHVVFRESRGLEETATPRDLGQDPADLVVLSFSDSDLAAFAAGWRRGRAALPSLRLANLA 60 MH++ + + + DLGQ P D++ LS +D++LA+ AA R+ RA SLR+A+L Sbjct: 1 MHLLLAQKGTIADGNEAIDLGQSPGDILFLSAADTELASIAAAHRQ-RAGARSLRIASLM 59 Query: 61 ELRHPLSVDTYIERTLSHARGILVRLIGGEPYWSYGLAAVHRLAKERGIALVVLPADGRD 120 L HP+SVDTY+ERT HA+ I+VR +GG Y+ Y L A++ A + VLP D + Sbjct: 60 NLMHPMSVDTYVERTARHAKLIVVRPLGGASYFRYVLEALYAAAVANKFQIAVLPGDDKP 119 Query: 121 DLRLDGFSTLPVSTLRRLKVLCDKGGPVAA-------QAVI--------AQLALASGLYA 165 D LD FST+ V +RL C +GG A QA+I A+ L +G++ Sbjct: 120 DPGLDPFSTVSVEDRQRLWGYCTEGGAENAGLFLDYAQALIDGGDKPQPARPLLKAGIWW 179 Query: 166 GPVVGEIDLPE-IGVYELRRGA-VAALPASDGRPLVLVTFYRSYLAAGDTAPVDALIEAL 223 P G I + E + + ELRR A ++ P V V FYR+ + +G+T PV+ALIEAL Sbjct: 180 -PGRGVIGVEEWVRLSELRRAVPTAQADRAEHEPTVAVCFYRALVQSGETKPVEALIEAL 238 Query: 224 REKGFDAHGVFVTSLKAAGVADWLRAQFAHCPPAAIVNATAFSAAG---DDGTTPFDAAL 280 +G A VFV+SLK L A FA P ++NAT F+ + D T ++ Sbjct: 239 AAEGVRALPVFVSSLKDPVSIGTLEAVFAEALPDVVMNATGFAVSAPGADRQPTVLESGG 298 Query: 281 CPVFQVALSTARREDWALSLRGLSPGDLAMHVVLPEVDGRLFAGVVSFKSPGERDPELQF 340 PV QV S + RE W S +GL DL M+V LPEVDGR+ + VSFK+ DP ++ Sbjct: 299 APVLQVIFSGSSREGWETSAQGLMARDLGMNVALPEVDGRVLSRAVSFKAASVYDPLVEA 358 Query: 341 AHLAHRPDAERVAAIAARVAAWHRLASKPAQKKQLALVLSNYPGRPHQIAHAVGLDALAS 400 + H P +R A A W +L + +++A+V++NYP R ++ + VGLD A Sbjct: 359 NIVGHEPLTDRARFAARLAANWTKLRRTRPEGRRVAIVMANYPNRDGRLGNGVGLDTPAG 418 Query: 401 VEALLADLAGAGFDLAPVRSLGDVLL---------------HRRLTWDVAEYRTALSSLP 445 +L + G+ + V GD L+ R T + Y+ +LP Sbjct: 419 TIEVLKAMTAEGYAVGNVPDDGDALIGFLMAGPTNAASRDREIRETISLNRYKGFFDALP 478 Query: 446 LQLQDDLARAWGTPEDDPECRDGAFHFSAVQSGKSIIAVQPERGEVTHRDADYHDLSRTP 505 ++Q+++ WG E DP DG F + G ++ +QP RG YH P Sbjct: 479 KKIQEEVTARWGAAEADPFFIDGVFALPLARFGDVLVGIQPARGYNIDPKETYHAPDLVP 538 Query: 506 RHAYVAFYLWLRQQ-GIDAVVHIGAHGTLEWLPGKSVALSSACWPEALTGDLPVVYPFIV 564 H Y+AFY +LR+ G A+VH+G HG LEWLPGK++ALS C+PE + G +P +YPFIV Sbjct: 539 PHGYLAFYAYLREVFGAHAIVHMGKHGNLEWLPGKALALSEECYPEVIFGPMPHLYPFIV 598 Query: 565 NDPGEAAQAKRRIGAVTIGHLPPPLAQAAVPEGLRSLERLLDEYSTADGLDPARRQRLIA 624 NDPGE QAKRR AV I HL PPL +A L+ LE L+DEY A G DP R + L Sbjct: 599 NDPGEGTQAKRRTSAVIIDHLTPPLTRAESYGPLKDLEALVDEYYEAAGGDPRRLRLLSR 658 Query: 625 AIRDEARIAGLEDDLSLAASVSAAEAIPQIDRFVCDLKESQFGDGLHIFG 674 I D R GL+ D + S A+ ++D ++CDLKE Q DGLH+FG Sbjct: 659 QILDLVRDIGLDHDAGIEKGDSENRALEKLDAYLCDLKEMQIRDGLHVFG 708 Score = 340 bits (871), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 193/428 (45%), Positives = 252/428 (58%), Gaps = 22/428 (5%) Query: 677 ACGEAERAALRDALAGRRVAPGPSGSPWRGRGDVLPTGRNLFAVDPRAVPTPSAHAQGVK 736 + GEAE L L GR VAPGPSG+P RGR DVLPTGRN ++VD R+VPTP+A+ G K Sbjct: 835 SSGEAEIKGLLTGLDGRFVAPGPSGAPTRGRPDVLPTGRNFYSVDSRSVPTPAAYELGKK 894 Query: 737 LAEELLRRHLQDHGDWPKGLVVDLWGSSTMRTAGEDFAMALHLAGIAPRWDHGSGRVSGY 796 AE L+RR+LQDHG+WP + WG+S MRT G+D A AL L G P WD S RV+GY Sbjct: 895 SAELLIRRYLQDHGEWPSSFGLTAWGTSNMRTGGDDIAQALALIGAKPVWDMASRRVTGY 954 Query: 797 DIIAPAELGRPRIDVTLRVSGLFRDVFSGLAQLFEAAAEAL------------------- 837 +II A LGR R+DVTLR+SG FRD F LF+ A A+ Sbjct: 955 EIIPLAVLGRTRVDVTLRISGFFRDAFPEQIALFDKAVRAVGALDEDDADNMIAARMRAE 1014 Query: 838 SERCDE--ADENPYRERIS-RVFGPRPGYYGVGIASMPDVFTEAAREAAGEAWLSASSWA 894 + R +E AD R R S RVFG +PG YG G+ ++ D R EA+LS +A Sbjct: 1015 TRRWEERGADAKEARRRASYRVFGSKPGAYGAGLQALVDEKGWETRGDLAEAYLSWGGYA 1074 Query: 895 LASDGEMRPDRAGIEARLAAADSFVHTQDLPETDLLLAADYAAHEAGIAAAARRLGTKVP 954 + + + +R E RL + ++ V QD E DLL + DY E G++AAA LG + P Sbjct: 1075 YGAGEDGKAERGLFEERLRSIEAVVQNQDNREHDLLDSDDYYQFEGGMSAAAEHLGGQRP 1134 Query: 955 ALYHLDATRPDRPHARALTEEISRVVRVRAANPAWIAGMMRHGFRGAAEISATLEHMAAF 1014 A+YH D +RP++P R+L EEI RVV R NP WI G+MRHG++GA EI+AT+++M AF Sbjct: 1135 AIYHNDHSRPEKPVIRSLEEEIGRVVHARVVNPKWIDGVMRHGYKGAFEIAATVDYMFAF 1194 Query: 1015 AHLAGAVPPHLFDLYYDATLGNDEVRCFMARENPAALAAIETCFSRLHEASLWQTRRNSI 1074 A GAV H F+ Y A + +++V F+ +NPAAL+ I + LW R NS Sbjct: 1195 AATTGAVRDHHFEAAYQAYIADEKVLGFLREKNPAALSEISERLLEAIDRGLWNPRSNSA 1254 Query: 1075 AAALQEAS 1082 L S Sbjct: 1255 RFELNSLS 1262 >alr1689 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Nos Nostoc sp. PCC 7120 Length = 1302 Score = 419 bits (1076), Expect = e-116, Method: Compositional matrix adjust. Identities = 261/735 (35%), Positives = 393/735 (53%), Gaps = 60/735 (8%) Query: 1 MHVVFRESRGLEETATPRDLGQDPADLVVLSFSDSDLAAFAAGWRRGRAALPSLRLANLA 60 MH + S G ++ L Q PA V+++ +D+D+ AA + A P++R+ANL Sbjct: 1 MHRISTTSVGWNQSEGVIFLEQTPAPFVLITAADTDIQTLAAAVPKLPATFPAIRVANLL 60 Query: 61 ELRHPLSVDTYIERTLSHARGILVRLIGGEPYWSYGLAAVHRLAKERGIALVVLPADGRD 120 L+ +S+DTY E+ L A+ I++RL+GG YW+YGL V + + GI L+V+P D Sbjct: 61 LLQQQISIDTYAEQVLELAQVIILRLLGGRSYWAYGLEVVQEIVERTGITLIVMPGDDAL 120 Query: 121 DLRLDGFSTLPVSTLRRLKVLCDKGGP---VAAQAVIAQLALASGLYAGPVVGEIDLPEI 177 D L ST PV T+ ++ +GG V A +I+ ++L + Y P + P + Sbjct: 121 DPELISQSTAPVGTVNQIWQYFYEGGVENIVNALQLISDVSLKT-TYKPPAPQRV--PRV 177 Query: 178 GVYELRRGA---------VAALPASDGR--PLVLVTFYRSYLAAGDTAPVDALIEALREK 226 G+YE G V P S P V + FYR++ AG+ +DAL AL ++ Sbjct: 178 GLYEWGMGTNRQGDKGNEVEFSPTSSQSLIPKVGILFYRAHYLAGNIQVIDALCAALWQR 237 Query: 227 GFDAHGVFVTSLK----AAGVADWLRAQFAHCPPAAIVNATAFSAAGDDGTTP----FDA 278 VF++SL+ A + D+ + + + + ++N T+FS A + P ++ Sbjct: 238 NLQPVPVFISSLRDPDVQAELIDFFQPKDSQ-QISLLLNTTSFSLARLETEAPQTELWEK 296 Query: 279 ALCPVFQVALSTARREDWALSLRGLSPGDLAMHVVLPEVDGRLFAGVVSFKSPGERDPEL 338 PV QV LS E W L GLSP D+AM+V LPEVDGR+ + VSFK+ R+P+L Sbjct: 297 LDVPVLQVILSGGFVEQWEAQLNGLSPRDIAMNVALPEVDGRIISRAVSFKAIQTRNPDL 356 Query: 339 QFAHLAHRPDAERVAAIAARVAAWHRLASKPAQKKQLALVLSNYPGRPHQIAHAVGLDAL 398 + + + P ++R+ +A A W L S+P Q++++AL+L+NYP R ++A+ VGLD Sbjct: 357 ETDVVVYEPISDRIDFVAQLAANWVHLRSQPPQQRRIALILANYPNRDGRLANGVGLDTP 416 Query: 399 ASVEALLADLAGAGFDLAPVRSLGDVLLHR-----------------RLTWDVAEYRTAL 441 S +L L +G+ ++ + + GD L+ + + EY+ Sbjct: 417 ESCVEILKALQQSGYVVSNLPANGDELIQLLTAGVTNDPEGREIRPVQQSLSSEEYQEYF 476 Query: 442 SSLPLQLQDDL----ARAWGTPEDDPECRDGAFHFSAVQSGKSIIAVQPERGEVTHRDAD 497 + LP +Q + R WG E + +Q G + +QP RG + + Sbjct: 477 AGLPATVQQGINERWGRDWGLGEQASNFPSSSCPIPGIQFGNVFVGIQPSRGYDIDPNLN 536 Query: 498 YHDLSRTPRHAYVAFYLWLRQQ-GIDAVVHIGAHGTLEWLPGKSVALSSACWPEALTGDL 556 YH P HAY+AFY W+R+ G DAVVH+G HG LEWLPGKS+ALSS C+PEA+ G + Sbjct: 537 YHAPDLEPTHAYLAFYYWVRESFGADAVVHVGKHGNLEWLPGKSLALSSNCYPEAVFGPM 596 Query: 557 PVVYPFIVNDPGEAAQAKRRIGAVTIGHLPPPLAQAAVPEGLRSLERLLDEYSTADGLDP 616 P +YPFIVNDPGE +QAKRR AV I HL PP+ +A + L+ LE L+DEY A+ LDP Sbjct: 597 PHLYPFIVNDPGEGSQAKRRAQAVIIDHLTPPMTRAELYGALQKLENLVDEYYEAESLDP 656 Query: 617 ARRQRLIAAIRDEARIAGLEDDLSLAASVSAAEAIPQ--------IDRFVCDLKESQFGD 668 +R + IRD R ++++L + E I +D ++C+LKE+Q D Sbjct: 657 SR----LGVIRDRIRDLVIQENLYKDLGIEKEEDIVNFESLILNSLDGYLCELKEAQIRD 712 Query: 669 GLHIFGQGACGEAER 683 GLHIFGQ G R Sbjct: 713 GLHIFGQCPQGRQLR 727 Score = 258 bits (660), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 154/425 (36%), Positives = 219/425 (51%), Gaps = 39/425 (9%) Query: 681 AERAALRDALAGRRVAPGPSGSPWRGRGDVLPTGRNLFAVDPRAVPTPSAHAQGVKLAEE 740 AE L L G + SG+P RGR +VLPTGRN +AVD RA+PT +A G K AE Sbjct: 858 AEITNLLHGLDGGYIPSAASGAPTRGRPEVLPTGRNFYAVDIRAIPTETAWDIGRKAAEN 917 Query: 741 LLRRHLQDHGDWPKGLVVDLWGSSTMRTAGEDFAMALHLAGIAPRWDHGSGRVSGYDIIA 800 L+ + Q+HG++PK L + +WG++TMRT G+D A AL L G+ P WD + RV DI+ Sbjct: 918 LVECYTQEHGEYPKTLGLSVWGTATMRTGGDDIAEALALLGVQPVWDGAARRVVDLDILP 977 Query: 801 PAELGRPRIDVTLRVSGLFRDVFSGLAQLFEAAAEALSERCDEADENPYRERIS------ 854 + LGRPR+DVTLR+SG FRD F L LFE A A++ + ++NP +I Sbjct: 978 LSILGRPRVDVTLRISGFFRDAFPNLMDLFEQAVNAVAALDEPPEQNPLAAQIRQDTDFW 1037 Query: 855 ----------------RVFGPRPGYYGVGIASMPDVFTEAAREAAGEAWLSASSWALASD 898 R+FG +PG YG G+ + + + A+++ S +A +S Sbjct: 1038 IQQGLTPETAFERSRYRLFGSKPGAYGAGLQGLIESQNWQNDQDLANAYINWSCYAYSSG 1097 Query: 899 GEMRPDRAGIEA--------------RLAAADSFVHTQDLPETDLLLAADYAAHEAGIAA 944 + AG E RL + QD E DLL + DY + G+ A Sbjct: 1098 ---KSQEAGTEINPPSPIPSPEAFTQRLGQMQIVLQNQDNREHDLLDSDDYYQFQGGLTA 1154 Query: 945 AARRLGTKVPALYHLDATRPDRPHARALTEEISRVVRVRAANPAWIAGMMRHGFRGAAEI 1004 A R L K P Y D + P +P R L EEI+RV R R NP WI GMMRHG++GA E+ Sbjct: 1155 AIRSLQGKNPETYFGDNSIPSQPRVRQLREEIARVYRSRVVNPKWIEGMMRHGYKGAFEM 1214 Query: 1005 SATLEHMAAFAHLAGAVPPHLFDLYYDATLGNDEVRCFMARENPAALAAIETCFSRLHEA 1064 +AT++ + A+ V +++ A L + V ++ +NP AL I ++ Sbjct: 1215 AATVDFLFAYDATTRCVEDYMYQGVMQAYLLDPVVCTYIENKNPHALRDIAERLLEANQR 1274 Query: 1065 SLWQT 1069 LW+ Sbjct: 1275 GLWEN 1279