BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0013.p (587 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll0994 [GEPR] COG0477 Permeases of the major facilitator superf... 468 e-131 PA3137 [GEPR] COG0477 Permeases of the major facilitator superfa... 347 3e-95 AGl781 [GEPR] COG0477 Permeases of the major facilitator superfa... 259 1e-68 PA1236 [GEPR] COG0477 Permeases of the major facilitator superfa... 246 8e-65 CC3715 [GEPR] COG0477 Permeases of the major facilitator superfa... 238 4e-62 >mll0994 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 537 Score = 468 bits (1205), Expect = e-131, Method: Compositional matrix adjust. Identities = 243/365 (66%), Positives = 296/365 (81%), Gaps = 1/365 (0%) Query: 1 MSGLALSSPSAA-PRAAAVAADPNRASMAVWISIVAAMIGAFMAILNIQITNASLLNIEG 59 M+ +A S P+ A P + AS VW+++V + +GAFMA+LNIQI NASL +I+G Sbjct: 1 MTSIASSMPAPARPARNETGSAGTAASPRVWVAVVGSSLGAFMAVLNIQIVNASLADIQG 60 Query: 60 GIGTGVDNGSWISTSYLIGEIVVIPLTDYLSRVFSFRKIIIGFATLFAIFSVACAFTHDL 119 IG G+D+G WIST+YLI EIVVIPLT +LS+VFS R +I A LF FSVACAF +L Sbjct: 61 AIGAGIDDGGWISTAYLIAEIVVIPLTGWLSQVFSLRNYLIANAVLFLAFSVACAFAANL 120 Query: 120 PSMIAMRGLQGFFGGVLIPMAFTLVFTKLPKAQQPVGLAMFALAVTFAPAIGPTIGGYLT 179 MI +R +QGF GGVLIPMAFT+V T LPKA+QP+GLA+FA++ TFAPAIGPTIGGYLT Sbjct: 121 GQMIVLRAIQGFTGGVLIPMAFTIVITLLPKARQPIGLALFAMSATFAPAIGPTIGGYLT 180 Query: 180 ENYGWQTIFFVNVIPTAVMVITLYFTLERQPMQLHLLREGDWLGIVTMAIGLSSLQAVLE 239 EN+GWQ IF+VN++P A+MV L+F+L+RQPM+L LL EGDW GI TMAIGL++LQ VLE Sbjct: 181 ENWGWQYIFYVNIVPGALMVGMLWFSLDRQPMRLALLGEGDWPGIATMAIGLAALQTVLE 240 Query: 240 EGNKNDWFGSPFVVRLSVIAAVALVAFLIVEFTVEKPLLNLRLLARRNFGFGMLANFLLG 299 EGNKNDWFGS FV+RL+++AAV+L F+ +E T PLLNLRLL RRNFGFG+LANF+LG Sbjct: 241 EGNKNDWFGSLFVLRLAIVAAVSLSLFVWIELTSSHPLLNLRLLLRRNFGFGILANFMLG 300 Query: 300 IALYGSVFILPQYLSRIQGYNAEQIGMVLAWTGLPQLVLIPLVPRLMQRFDPRIIISVGF 359 ALYGSVFILP YL+RIQGYNAEQIG+VLAWTGLPQL+LIPLVP LMQRFD R++I GF Sbjct: 301 TALYGSVFILPVYLARIQGYNAEQIGLVLAWTGLPQLLLIPLVPYLMQRFDVRLVIVTGF 360 Query: 360 ALFGS 364 ALF + Sbjct: 361 ALFAA 365 Score = 156 bits (395), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 80/154 (51%), Positives = 106/154 (68%), Gaps = 2/154 (1%) Query: 357 VGFALFGSVYLLPAYLGQVQRYNAEQIGQVLAWTGLPQLILIPLVPKLMQRFDPRFIAFT 416 +G AL+GSV++LP YL ++Q YNAEQIG VLAWTGLPQL+LIPLVP LMQRFD R + T Sbjct: 299 LGTALYGSVFILPVYLARIQGYNAEQIGLVLAWTGLPQLLLIPLVPYLMQRFDVRLVIVT 358 Query: 417 GMILFAVSSFMNIAMSLDYSGDQFFVPNIVRAIGQAIMLAPLSAVSLGSVAPQDAAAASG 476 G LFA S+FMN+ M+ Y+ DQ F PNIVRAIGQA++ APLSA+++ + ++A +AS Sbjct: 359 GFALFAASNFMNVHMTAGYASDQLFWPNIVRAIGQALVFAPLSAIAVSGIEQENAGSASS 418 Query: 477 ISNX--RLRAVRRLQLHEHLHDQRLCHRPAVLAQ 508 + N L + L + +R + VL Q Sbjct: 419 LFNMIRNLGGAVGIALLQTFLTKRQQYHSNVLVQ 452 >PA3137 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 499 Score = 347 bits (891), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 162/331 (48%), Positives = 239/331 (72%) Query: 33 IVAAMIGAFMAILNIQITNASLLNIEGGIGTGVDNGSWISTSYLIGEIVVIPLTDYLSRV 92 +++AM+GAFMA+L+IQITN+SL +I+G + ++ GSWISTSYL+ EI++IP+T +L ++ Sbjct: 1 MLSAMLGAFMAVLDIQITNSSLKDIQGALAATLEEGSWISTSYLVAEIIMIPMTAWLVQL 60 Query: 93 FSFRKIIIGFATLFAIFSVACAFTHDLPSMIAMRGLQGFFGGVLIPMAFTLVFTKLPKAQ 152 S R++ + + F + S+ C+F +L SMI R +QGF GG LIP+AFTL KLP+ Sbjct: 61 LSARRLAVMISVGFLVSSLLCSFAWNLESMIVFRAMQGFTGGALIPLAFTLALVKLPEHH 120 Query: 153 QPVGLAMFALAVTFAPAIGPTIGGYLTENYGWQTIFFVNVIPTAVMVITLYFTLERQPMQ 212 +P G+A+FA+ TFAP+IGPT+GG+LTEN+GW+ IF++NV P +M+ L + LE++ Sbjct: 121 RPKGMALFAITATFAPSIGPTLGGWLTENFGWEYIFYINVPPGLLMIAGLLYGLEKKAPH 180 Query: 213 LHLLREGDWLGIVTMAIGLSSLQAVLEEGNKNDWFGSPFVVRLSVIAAVALVAFLIVEFT 272 LL+ D+ GIVT+ IGL LQ LEEG++ DW S +V L +A +LV F+I++ + Sbjct: 181 WELLKSTDYAGIVTLGIGLGCLQVFLEEGHRKDWLESQLIVSLGSVALFSLVLFVILQLS 240 Query: 273 VEKPLLNLRLLARRNFGFGMLANFLLGIALYGSVFILPQYLSRIQGYNAEQIGMVLAWTG 332 PL++L +L RNFG +++ LG+ LYGS+++LP YL++IQGYNA QIG V+ W G Sbjct: 241 RPNPLIDLGILRNRNFGLASISSIGLGMGLYGSIYVLPLYLAQIQGYNAMQIGEVIMWMG 300 Query: 333 LPQLVLIPLVPRLMQRFDPRIIISVGFALFG 363 +PQL LIPLVP+LM+ PR++ + GF LFG Sbjct: 301 IPQLFLIPLVPKLMKLVSPRLLCAAGFGLFG 331 >AGl781 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 527 Score = 259 bits (662), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 136/370 (36%), Positives = 213/370 (57%), Gaps = 1/370 (0%) Query: 31 ISIVAAMIGAFMAILNIQITNASLLNIEGGIGTGVDNGSWISTSYLIGEIVVIPLTDYLS 90 I+ A + G FM+IL+IQI +ASL I+ G+G G D +W+ TSYLI E+++IPL+ L+ Sbjct: 25 IAFFAMVFGMFMSILDIQIVSASLAEIQAGLGAGSDEIAWVQTSYLIAEVIMIPLSGTLA 84 Query: 91 RVFSFRKIIIGFATLFAIFSVACAFTHDLPSMIAMRGLQGFFGGVLIPMAFTLVFTKLPK 150 R+ S R + A F + S CA ++ MI R +QGF GG +IP F FT P Sbjct: 85 RILSTRVLFATCAAGFTLSSALCATATNIDQMIVYRAIQGFIGGGMIPSVFAAAFTIFPP 144 Query: 151 AQQPVGLAMFALAVTFAPAIGPTIGGYLTENYGWQTIFFVNVIPTAVMVITLYFTLERQP 210 +++ V + L T AP IGPT+GGYL+ + W +F VN+IP ++ I + ++ Sbjct: 145 SKRSVVSPIIGLVATLAPTIGPTVGGYLSNAFSWHWLFLVNIIPGIIVTILTWSLIDFDK 204 Query: 211 MQLHLLREGDWLGIVTMAIGLSSLQAVLEEGNKNDWFGSPFVVRLSVIAAVALVAFLIVE 270 + L ++ DW G+++MA+ L SL+ VLEEGN DWF +V SV + V F Sbjct: 205 PETSLWKKFDWWGLISMAVFLGSLEYVLEEGNNKDWFNDEHIVIGSVAMVIGAVVFFWRA 264 Query: 271 FTVEKPLLNLRLLARRNFGFGMLANFLLGIALYGSVFILPQYLSRIQGYNAEQIGMVLAW 330 F V+ P++++R A RNF G L +F++GI LYG ++ P YL R++GY+A IG + Sbjct: 265 FKVDFPVVDIRAFADRNFSIGSLFSFVMGIGLYGLTYLYPLYLGRVRGYDALMIGETMFV 324 Query: 331 TGLPQLVLIPLVPRLMQRFDPRIIISVGFALFGSVYLLPAYLGQVQRYNAEQIGQVLAWT 390 +GL P+ ++ + DPR+++++GF FG + Y+ + I Q+L Sbjct: 325 SGLAMFFTAPIAGKVSTKLDPRVMMAIGFISFGCGTWIMTYVTTDWDFYELLIPQILRGF 384 Query: 391 GLPQLILIPL 400 GL + ++P+ Sbjct: 385 GL-MMCMVPI 393 Score = 81.3 bits (199), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 47/163 (28%), Positives = 79/163 (48%), Gaps = 2/163 (1%) Query: 357 VGFALFGSVYLLPAYLGQVQRYNAEQIGQVLAWTGLPQLILIPLVPKLMQRFDPRFIAFT 416 +G L+G YL P YLG+V+ Y+A IG+ + +GL P+ K+ + DPR + Sbjct: 292 MGIGLYGLTYLYPLYLGRVRGYDALMIGETMFVSGLAMFFTAPIAGKVSTKLDPRVMMAI 351 Query: 417 GMILFAVSSFMNIAMSLDYSGDQFFVPNIVRAIGQAIMLAPLSAVSLGSVAPQDAAAASG 476 G I F +++ ++ D+ + +P I+R G + + P++ ++LG++ P ASG Sbjct: 352 GFISFGCGTWIMTYVTTDWDFYELLIPQILRGFGLMMCMVPINNIALGTLPPARIRNASG 411 Query: 477 ISNX--RLRAVRRLQLHEHLHDQRLCHRPAVLAQHRPCDRPGA 517 + N L L + L QR LA+H P A Sbjct: 412 LFNLTRNLGGAVGLAVINTLLSQRTDDHYVRLAEHVSYSNPQA 454 >PA1236 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 503 Score = 246 bits (629), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 143/355 (40%), Positives = 234/355 (65%), Gaps = 1/355 (0%) Query: 18 VAADPNRASMAVWISIVAAMIGAFMAILNIQITNASLLNIEGGIGTGVDNGSWISTSYLI 77 ++AD ++ S+ W+++ + G FMA +N+ +T+A+L IEG +G + GSWIST+YL+ Sbjct: 1 MSAD-DKVSLRAWVAVTGGLFGCFMAGMNVHVTSAALPEIEGALGATFEEGSWISTAYLV 59 Query: 78 GEIVVIPLTDYLSRVFSFRKIIIGFATLFAIFSVACAFTHDLPSMIAMRGLQGFFGGVLI 137 EI +IPLT +L VFS R++++ + +F + S++CA +L ++I +R +QG G VLI Sbjct: 60 AEISMIPLTAWLVEVFSLRRVMLLGSLVFLLSSLSCALAPNLSTLILIRVIQGASGAVLI 119 Query: 138 PMAFTLVFTKLPKAQQPVGLAMFALAVTFAPAIGPTIGGYLTENYGWQTIFFVNVIPTAV 197 P++ L+ T+LP ++ P+G+A+F+L+ + A A GP+IGG+L + Y W+ IF + ++P Sbjct: 120 PLSMQLILTELPSSRIPLGMALFSLSNSVAQAAGPSIGGWLADAYSWRWIFLLQLLPGIA 179 Query: 198 MVITLYFTLERQPMQLHLLREGDWLGIVTMAIGLSSLQAVLEEGNKNDWFGSPFVVRLSV 257 ++ + +++ + LR+ DWLGI M GL +LQ VLEEG + DWF S F+ +V Sbjct: 180 LLAAVAWSIRPRDGDRERLRQADWLGIGAMVAGLGALQIVLEEGGRRDWFESGFIRTFAV 239 Query: 258 IAAVALVAFLIVEFTVEKPLLNLRLLARRNFGFGMLANFLLGIALYGSVFILPQYLSRIQ 317 +A +AL+ F+ + +P +NLRLL NFG LA + G A +G VF++P YLS++Q Sbjct: 240 LAVLALLLFVQRQLWGARPFINLRLLGSYNFGVSSLAMAVFGAATFGLVFLVPNYLSQLQ 299 Query: 318 GYNAEQIGMVLAWTGLPQLVLIPLVPRLMQRFDPRIIISVGFALFGSVYLLPAYL 372 G+NA QIG L GL QL+L PL+PRLM+ +P+++++ GFA+ + A+L Sbjct: 300 GFNARQIGDSLILYGLVQLLLAPLLPRLMRWLNPKLLVAGGFAIMALGCWMGAHL 354 >CC3715 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 533 Score = 238 bits (606), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 138/363 (38%), Positives = 206/363 (56%), Gaps = 15/363 (4%) Query: 9 PSAAPRAAAVAADPNRASMAVWISIV----AAMIGAFMAILNIQITNASLLNIEGGIGTG 64 P+ +P A A P + W + A +IG FMAIL+IQI ASL I+ G+G Sbjct: 7 PADSPSAPAT---PGATAPVDWTKLFLGFGAMVIGQFMAILDIQIVAASLPQIQAGVGAS 63 Query: 65 VDNGSWISTSYLIGEIVVIPLTDYLSRVFSFRKIIIGFATLFAIFSVACAFTHDLPSMIA 124 D SWI T+YLI E+V+IPL+ YLSR++ +K+ + F + S+ + + MI Sbjct: 64 TDQVSWIQTAYLIPEVVMIPLSGYLSRLWGTQKLYLASCAGFIVMSILTGLSTSIDMMII 123 Query: 125 MRGLQGFFGGVLIPMAFTLVFTKLPKAQQPVGLAMFALAVTFAPAIGPTIGGYLTENYGW 184 R LQGF GG +IP F + FT P ++ + L VT AP +GPT+GG+LTE W Sbjct: 124 TRALQGFIGGAMIPTVFAVAFTAFPPERRVTASVIMGLIVTLAPTVGPTLGGHLTEWLSW 183 Query: 185 QTIFFVNVIPTAVMVITLYFTLER----QPMQLHLLREGDWLGIVTMAIGLSSLQAVLEE 240 + +FF+NV PT ++V+ F + R L + DW G+ MA+ L S+Q VLEE Sbjct: 184 RWLFFINV-PTGLIVL---FGVARWGDFDKGDPSLAKGFDWFGLAVMAVFLMSMQYVLEE 239 Query: 241 GNKNDWFGSPFVVRLSVIAAVALVAFLIVEFTVEKPLLNLRLLARRNFGFGMLANFLLGI 300 G K DW ++ L+V+A V F+ + T P++ LR A RNF G+L + G Sbjct: 240 GAKEDWLSDSLILWLTVVAVFGGVVFVWRQLTYRNPIVELRAFANRNFTVGVLMTAVSGA 299 Query: 301 ALYGSVFILPQYLSRIQGYNAEQIGMVLAWTGLPQLVLIPLVPRLMQRFDPRIIISVGFA 360 +L+G F+LPQ+L R++ Y+A ++G + +GL + P+ RL+++ DPR+ + VGF Sbjct: 300 SLFGGTFLLPQFLGRVRHYSASEVGTTMVISGLSMFLTGPIAGRLVRKTDPRLPMCVGFL 359 Query: 361 LFG 363 L G Sbjct: 360 LAG 362 Score = 63.5 bits (153), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 33/122 (27%), Positives = 63/122 (51%) Query: 358 GFALFGSVYLLPAYLGQVQRYNAEQIGQVLAWTGLPQLILIPLVPKLMQRFDPRFIAFTG 417 G +LFG +LLP +LG+V+ Y+A ++G + +GL + P+ +L+++ DPR G Sbjct: 298 GASLFGGTFLLPQFLGRVRHYSASEVGTTMVISGLSMFLTGPIAGRLVRKTDPRLPMCVG 357 Query: 418 MILFAVSSFMNIAMSLDYSGDQFFVPNIVRAIGQAIMLAPLSAVSLGSVAPQDAAAASGI 477 +L +M ++ D+ +F R +G I + +++ ++ P ASG+ Sbjct: 358 FLLAGFGMYMAHGVTKDWGFWEFAGVQACRGVGVMIAMIATQQITMSTLPPHMVKNASGL 417 Query: 478 SN 479 N Sbjct: 418 VN 419