BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0008.p (381 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc2701 [E] COG0404 Glycine cleavage system T protein (aminometh... 531 e-151 SMc02047 [E] COG0404 Glycine cleavage system T protein (aminomet... 519 e-147 PA2442 [E] COG0404 Glycine cleavage system T protein (aminomethy... 454 e-127 CC3355 Non COG 347 3e-95 BMEII0559 [E] COG0404 Glycine cleavage system T protein (aminome... 311 1e-84 >AGc2701 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 379 Score = 531 bits (1369), Expect = e-151, Method: Compositional matrix adjust. Identities = 253/377 (67%), Positives = 304/377 (80%) Query: 5 ETSPLKQTPLHALHLARGAKMVPFAGYDMPVQYAAGVLKEHLHTRKEAGLFDVSHMGQLV 64 +T+ LK TPLH+LH + GA+MVPFAGYDMPVQY AGVLKEHL TR AGLFDVSHMGQ++ Sbjct: 3 DTAALKTTPLHSLHTSLGARMVPFAGYDMPVQYPAGVLKEHLQTRTSAGLFDVSHMGQVI 62 Query: 65 LKAKSGKVADAALALEKLVPQDIVGIAPGRQRYAQFTNNEGGLLDDLMVANFGDHLFLVV 124 LKA+SG DAA ALEKLVP DI G+ GRQRY FT++ G +LDDLM+ N GDHLF+VV Sbjct: 63 LKARSGNNEDAARALEKLVPVDIFGLKEGRQRYGFFTDDNGNILDDLMITNRGDHLFVVV 122 Query: 125 NAACKEEDEAHLRAHLSDSCEIVALADRALIALQGPKAESALAKLCPDVSSMKFMDAGPR 184 NA+CK+ D AH++AHLSD+CEI L DRALIALQGP+AE+ LA+L VS MKFMD Sbjct: 123 NASCKDADVAHMKAHLSDTCEITLLVDRALIALQGPRAEAVLAELWAGVSEMKFMDVQGV 182 Query: 185 RVADIDCFVSRSGYTGEDGFEISVPADKAEALVTALLDNPDVLPIGLGARDSLRLEAGLC 244 + D+ C VSRSGY+GEDGFEISVPADKAE + ALL++PD PIGLGARDSLRLEAGLC Sbjct: 183 PLHDVPCIVSRSGYSGEDGFEISVPADKAEEIAKALLEHPDCEPIGLGARDSLRLEAGLC 242 Query: 245 LYGHDIDTTTTPVEGALEWSVQKVRRSGGARAGGFPGADKILAQFADGAGRRRVGLKPDG 304 LYG+DIDTTT+P+E +LEW++QK RR+GG R GGFPGA++IL + DG RRRVGLKP+G Sbjct: 243 LYGNDIDTTTSPIEASLEWAIQKARRAGGEREGGFPGAERILRELKDGTSRRRVGLKPEG 302 Query: 305 RAPVREGAALFADAASTEQIGKVTSGGFGPSLNAPVAMGYLPTALSTAGTTVFAEVRGQR 364 +APVR + LFADA +IG+VTSGGFGPS+ PVAMGY+P + + GT +FAEVRG+ Sbjct: 303 KAPVRGHSKLFADAEGVTEIGEVTSGGFGPSVEGPVAMGYVPVSYAAPGTAIFAEVRGKY 362 Query: 365 LPLKVAATPFVPNTYKR 381 LP+ VAA PF+ TYKR Sbjct: 363 LPVTVAALPFIKPTYKR 379 >SMc02047 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase) Sme Sinorhizobium meliloti Length = 379 Score = 519 bits (1337), Expect = e-147, Method: Compositional matrix adjust. Identities = 249/377 (66%), Positives = 295/377 (78%) Query: 5 ETSPLKQTPLHALHLARGAKMVPFAGYDMPVQYAAGVLKEHLHTRKEAGLFDVSHMGQLV 64 + S LK TPLHALHL+ GA+MVPFAGYDMPVQY GVLKEHLHTR AGLFDVSHMGQ+V Sbjct: 3 DVSTLKHTPLHALHLSLGARMVPFAGYDMPVQYPEGVLKEHLHTRAAAGLFDVSHMGQIV 62 Query: 65 LKAKSGKVADAALALEKLVPQDIVGIAPGRQRYAQFTNNEGGLLDDLMVANFGDHLFLVV 124 ++ KSGK+ DAALALEKLVP D++G+A GRQRY FTN GG+LDDLM+ N GDHLFLVV Sbjct: 63 VRPKSGKIEDAALALEKLVPADVLGLAEGRQRYGLFTNAAGGILDDLMIVNRGDHLFLVV 122 Query: 125 NAACKEEDEAHLRAHLSDSCEIVALADRALIALQGPKAESALAKLCPDVSSMKFMDAGPR 184 NAACK+ D AHL+ L C++ L DRALIALQGP+A + L +L DVSSM+FMD Sbjct: 123 NAACKDADLAHLKDGLGSVCDVTMLTDRALIALQGPRAGAVLCELWADVSSMRFMDVTEA 182 Query: 185 RVADIDCFVSRSGYTGEDGFEISVPADKAEALVTALLDNPDVLPIGLGARDSLRLEAGLC 244 + D+ C +SRSGYTGEDGFEIS+PA+ A + LL++PDVLPIGLGARDSLRLEAGLC Sbjct: 183 DLHDVSCIISRSGYTGEDGFEISIPAEAAVDVTQRLLEHPDVLPIGLGARDSLRLEAGLC 242 Query: 245 LYGHDIDTTTTPVEGALEWSVQKVRRSGGARAGGFPGADKILAQFADGAGRRRVGLKPDG 304 LYG+DIDT T+P+E LEW++QK RR+GG RAGGFPGA +ILA+ DG RRRVGL+P+G Sbjct: 243 LYGNDIDTNTSPIEAGLEWAIQKSRRAGGERAGGFPGAGRILAELTDGVSRRRVGLRPEG 302 Query: 305 RAPVREGAALFADAASTEQIGKVTSGGFGPSLNAPVAMGYLPTALSTAGTTVFAEVRGQR 364 RAPVR A LFAD G VTSGGFGPS++ PVAMGY+ + GT +FAEVRG+ Sbjct: 303 RAPVRGNANLFADEEGRTAAGTVTSGGFGPSVDGPVAMGYVDAEHAEVGTRLFAEVRGKY 362 Query: 365 LPLKVAATPFVPNTYKR 381 LP+ V A PF+ TYKR Sbjct: 363 LPIAVTALPFIKQTYKR 379 >PA2442 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase) Pae Pseudomonas aeruginosa Length = 373 Score = 454 bits (1169), Expect = e-127, Method: Compositional matrix adjust. Identities = 234/374 (62%), Positives = 273/374 (72%), Gaps = 8/374 (2%) Query: 9 LKQTPLHALHLARGAKMVPFAGYDMPVQYAAGVLKEHLHTRKEAGLFDVSHMGQLVLKAK 68 L +TPLHALHL GAKMVPFAGYDMPVQY AGVLKEHLHTR++AGLFDVSHMGQ+ L Sbjct: 6 LAKTPLHALHLELGAKMVPFAGYDMPVQYPAGVLKEHLHTREQAGLFDVSHMGQIRLVG- 64 Query: 69 SGKVADAALALEKLVPQDIVGIAPGRQRYAQFTNNEGGLLDDLMVANFGDHLFLVVNAAC 128 AD ALALE LVP DI+ + G+QRYA FT+ +GG+LDDLMVAN GD L LVVNAAC Sbjct: 65 ----ADVALALESLVPVDILDLPVGQQRYALFTDEQGGILDDLMVANLGDCLLLVVNAAC 120 Query: 129 KEEDEAHLRAHLSDSCEIVAL-ADRALIALQGPKAESALAKLCPDVSSMKFMDAGPRRVA 187 K +D AHLR HL C + L +RAL+ALQGP A L +L P V+ M FM + Sbjct: 121 KHQDLAHLRRHLEGRCSVEPLFEERALLALQGPAAVRVLERLAPQVAQMTFMQFARVELL 180 Query: 188 DIDCFVSRSGYTGEDGFEISVPADKAEALVTALLDNPDVLPIGLGARDSLRLEAGLCLYG 247 DC+VSRSGYTGEDG+EISVPA AEAL LL P+V PIGLGARDSLRLEAGLCLYG Sbjct: 181 GQDCYVSRSGYTGEDGYEISVPAAHAEALARRLLAEPEVAPIGLGARDSLRLEAGLCLYG 240 Query: 248 HDIDTTTTPVEGALEWSVQKVRRSGGARAGGFPGADKILAQFADGAGRRRVGLKPDGRAP 307 HD+D+ TTPVE +L W++ K RR+ G RAGGFPGA++I AQ A G +RVG P GR P Sbjct: 241 HDMDSATTPVEASLGWAISKARRADGVRAGGFPGAERIFAQQAQGVASKRVGFLPQGRMP 300 Query: 308 VREGAALFADAASTEQIGKVTSGGFGPSLNAPVAMGYLPTALSTAGTTVFAEVRGQRLPL 367 VREGA + A IGKV+SGGFGPSLNAP+AMGY+P+ L+ G+ V A VRG+ + L Sbjct: 301 VREGAEIV--DAQGRAIGKVSSGGFGPSLNAPLAMGYVPSELAGLGSEVTAMVRGKPVTL 358 Query: 368 KVAATPFVPNTYKR 381 V+ PFV Y R Sbjct: 359 VVSKMPFVAQRYYR 372 >CC3355 Non COG Length = 375 Score = 347 bits (889), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 192/379 (50%), Positives = 243/379 (64%), Gaps = 12/379 (3%) Query: 4 SETSPLKQTPLHALHLARGAKMVPFAGYDMPVQYAAGVLKEHLHTRKEAGLFDVSHMGQL 63 S LK+TPL+ H+A GA+MVPFAGY MPVQY GVLKEHL TR+ AGLFDVSHMGQ Sbjct: 6 SSDQDLKKTPLYDAHVAAGARMVPFAGYSMPVQYKDGVLKEHLWTREHAGLFDVSHMGQA 65 Query: 64 VLKAKSGKVADAALALEKLVPQDIVGIAPGRQRYAQFTNNEGGLLDDLMVANFG-DHLFL 122 ++ + + A + EK+V D G+ G+QRY N +GG++DDLM A D LF+ Sbjct: 66 RIRGE-----NPAKSFEKVVSADYQGLKAGKQRYGVLLNADGGIVDDLMTARPDEDGLFV 120 Query: 123 VVNAACKEEDEAHLRAHLSDSCEIVALADRALIALQGPKAESALAKLCPDVSSMKFMDAG 182 VVN ACK+ D A + L+ + L DRAL+ALQGP+A + LA P+ + M FMDA Sbjct: 121 VVNGACKDNDYAIIARELAGEATVTRLEDRALLALQGPEAAAVLAAHVPEAAQMVFMDAK 180 Query: 183 PRRVADIDCFVSRSGYTGEDGFEISVPADKAEALVTALLDNPDVLPIGLGARDSLRLEAG 242 +D +SRSGYTGEDG+EISVPAD AE + LL + V PIGLGARDSLRLEAG Sbjct: 181 ALSAFGVDAIISRSGYTGEDGYEISVPADAAERVWNTLLADERVKPIGLGARDSLRLEAG 240 Query: 243 LCLYGHDIDTTTTPVEGALEWSVQKVRRSGGARAGGFPGADKILAQFADGAGRRRVGLKP 302 L LYGHD+D T +P+E L ++V + RR AG + GA +I + A R RV LK Sbjct: 241 LPLYGHDLDETVSPIEAGLNFAVGRSRRE----AGDYLGAARIAKELAGELSRVRVNLKV 296 Query: 303 DGRAPVREGAALFADAASTEQIGKVTSGGFGPSLNAPVAMGYLPTALSTAGTTVFAEVRG 362 AP REGA + +A + IGKVTSGGF PSL P+A+G+ P A + GT + VRG Sbjct: 297 LEGAPAREGAEIADEAGNV--IGKVTSGGFAPSLGFPIAIGFAPPAYAAVGTKLKVIVRG 354 Query: 363 QRLPLKVAATPFVPNTYKR 381 + +V A+PFVPN Y R Sbjct: 355 KPAAAEVVASPFVPNRYVR 373 >BMEII0559 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase) Bme Brucella melitensis Length = 367 Score = 311 bits (798), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 179/379 (47%), Positives = 228/379 (60%), Gaps = 17/379 (4%) Query: 5 ETSPLKQTPLHALHLARGAKMVPFAGYDMPVQYAAGVLKEHLHTRKEAGLFDVSHMGQLV 64 +T+ L PL LH GA+ FAG++MP Y GV+KEHLHTR AGLFD+SHM + Sbjct: 3 DTAHLNTLPLQDLHEKAGARFGGFAGWNMPTTYPLGVMKEHLHTRDHAGLFDISHMKLVE 62 Query: 65 LKAKSGKVADAALALEKLVPQDIVGIAPGRQRYAQFTNNEGGLLDDLMVANFGDHLFLVV 124 + ADAA L + P D + G+ +Y F N+ GG+LDDL+V G+ F+VV Sbjct: 63 VSG-----ADAAALLAETCPLDPTILKTGQSKYTFFLNDNGGVLDDLIVTRLGEDRFMVV 117 Query: 125 -NAACKEEDEAHLRAHLSDSCEIVALADRALIALQGPKAESALAKLCPDVSSMKFMDA-G 182 NA + D HL S V DR +ALQGP+AE+ + + + FM Sbjct: 118 ANAGNADADIEHLNEAASGKAVKVNPLDRVFLALQGPEAEAVITDAGLPGADLAFMSGFE 177 Query: 183 PRRVADIDCFVSRSGYTGEDGFEISVPADKAEALVTALLDNPDVLPIGLGARDSLRLEAG 242 P++ F++RSGYTGEDGFEI +PAD+A AL LL + V IGL ARDSLRLEAG Sbjct: 178 PKQ----SWFMTRSGYTGEDGFEIGLPADEARALAEKLLADERVEWIGLAARDSLRLEAG 233 Query: 243 LCLYGHDIDTTTTPVEGALEWSVQKVRRSGGARAGGFPGADKILAQFADGAGRRRVGLKP 302 LCL+G DI T PV L W++ K R A F GA +L A GA +RVGLKP Sbjct: 234 LCLHGQDITPETDPVSAGLTWAITKAVREKAA----FNGAKAVLDAIAKGASAKRVGLKP 289 Query: 303 DGRAPVREGAALFADAASTEQIGKVTSGGFGPSLNAPVAMGYLPTALSTAGTTVFAEVRG 362 +GR PVR GA LF + S QIG VTSGGFGPS PVAMGY+ +L+T GT VFA+VRG Sbjct: 290 EGRQPVRAGADLFDE--SGRQIGTVTSGGFGPSAGFPVAMGYVEASLATPGTRVFADVRG 347 Query: 363 QRLPLKVAATPFVPNTYKR 381 ++P+ V A PF P+ Y++ Sbjct: 348 NKVPVDVHALPFTPHRYRK 366