BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0024.0001.p (438 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value dgoT [GEPR] COG0477 Permeases of the major facilitator superfami... 126 1e-28 STM3827 [GEPR] COG0477 Permeases of the major facilitator superf... 124 5e-28 BS_yjmG [GEPR] COG0477 Permeases of the major facilitator superf... 124 5e-28 RSp0828 [GEPR] COG0477 Permeases of the major facilitator superf... 123 7e-28 RSp1614 [GEPR] COG0477 Permeases of the major facilitator superf... 123 9e-28 >dgoT [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 445 Score = 126 bits (316), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 103/402 (25%), Positives = 179/402 (44%), Gaps = 29/402 (7%) Query: 24 LLFLFMVVNFADKIVVGLAGVPIKKEMGLTQEQFGDLGSSFFLLFSISAIVVGFIVNRVA 83 ++F+ +V+ + D+ + +A I++E G+T+ + G + S+F L+++ I G+ ++RV Sbjct: 35 MIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVG 94 Query: 84 TRWVLLILAVIWSLAQFPMVGTVSFTTLVICRIILGAGEGPAFSVAAHAIYKWFPDEKRT 143 +R I WS+A +L+ R I G E PAF + WFP+ +R Sbjct: 95 SRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERA 154 Query: 144 LPTAILSQGSAFGVILAVPALNWIIVNHSWHHAFGALGIVGLIWAVAWFALGKE------ 197 + G G+ P L WI SWH F G +G+IW++ WF + + Sbjct: 155 SAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKG 214 Query: 198 ------------GPLVSTSAVTADEPRIPYL----KLLTSRTFIGCVVATFGAYWALSLG 241 G LV A E R P KL+ R IG + F L Sbjct: 215 ISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVASTLWFF 274 Query: 242 LTWFTSFIIEGLGFSQHQAGFVSILPWIFGATIVLLTGWISQLMLTRGFTTRGARGVLGS 301 LTWF +++ + G + +AGF++ +P++ VLL+GW++ L++ +GF+ AR Sbjct: 275 LTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPII 334 Query: 302 VPLIVGGAILAMLPYAPPGGIM--IALLVIGSGLCGSIYVVCPPMLGEFTPVSQRGAIIA 359 L++ I+ P IM +AL G+G + ++ P+ G Sbjct: 335 CGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITW----SLVSSLAPMRLIGLTGG 390 Query: 360 IYGALYTISGILAPMVMGNVIQ-HAATPMAGYMSGFTINAAI 400 ++ + GI P+V+G + Q + P Y+S + A+ Sbjct: 391 VFNFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGAL 432 >STM3827 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 445 Score = 124 bits (311), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 99/394 (25%), Positives = 177/394 (44%), Gaps = 29/394 (7%) Query: 24 LLFLFMVVNFADKIVVGLAGVPIKKEMGLTQEQFGDLGSSFFLLFSISAIVVGFIVNRVA 83 ++F+ +V+ + D+ + +A + I+KE G+T+ + G + S+F L+++ I G+ ++R+ Sbjct: 35 MIFITVVICYVDRANLAVASMHIQKEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRIG 94 Query: 84 TRWVLLILAVIWSLAQFPMVGTVSFTTLVICRIILGAGEGPAFSVAAHAIYKWFPDEKRT 143 +R I WS+A +L+ R I G E PAF + WFP+ +R Sbjct: 95 SRLTYFIAIFGWSVATLLQGFATGLLSLIGLRAITGIFEAPAFPANNRMVTSWFPEHERA 154 Query: 144 LPTAILSQGSAFGVILAVPALNWIIVNHSWHHAFGALGIVGLIWAVAWFALGKE------ 197 + G G+ P L WI SWH F G +G+IW++ WF + + Sbjct: 155 SAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLVWFKVYQPPRLTKS 214 Query: 198 ------------GPLVSTSAVTADEPRIPYL----KLLTSRTFIGCVVATFGAYWALSLG 241 G LV A E R P KL+ R +G + F L Sbjct: 215 LSQAELEYIRDGGGLVDGDAPAKKEARQPLTKADWKLVFHRKLVGVYLGQFAVNSTLWFF 274 Query: 242 LTWFTSFIIEGLGFSQHQAGFVSILPWIFGATIVLLTGWISQLMLTRGFTTRGARGVLGS 301 LTWF +++ + G + +AGF++ +P++ VLL+GW++ ++ +GF+ AR Sbjct: 275 LTWFPNYLTQEKGITALKAGFMTTVPFLAAFFGVLLSGWLADKLVKKGFSLGVARKTPII 334 Query: 302 VPLIVGGAILAMLPYAPPGGIM--IALLVIGSGLCGSIYVVCPPMLGEFTPVSQRGAIIA 359 L++ I+ P IM +A+ G+G + ++ P+ G Sbjct: 335 CGLLISTCIMGANYTNDPLWIMALMAIAFFGNGFAS----ITWSLISSLAPMRLIGLTGG 390 Query: 360 IYGALYTISGILAPMVMGNVIQ-HAATPMAGYMS 392 ++ + + GI P+V+G + Q + P Y+S Sbjct: 391 MFNFIGGLGGISVPLVIGYLAQSYGFAPALVYIS 424 >BS_yjmG [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 422 Score = 124 bits (310), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 105/379 (27%), Positives = 178/379 (46%), Gaps = 24/379 (6%) Query: 24 LLFLFM--VVNFADKIVVGLAGVPIKKEMGLTQEQFGDLGSSFFLLFSISAIVVGFIVNR 81 +LFLF+ V+N+ D+ + +A I+ ++ L+ Q G + SSF + ++I + G +R Sbjct: 10 ILFLFLAGVINYLDRSALSIAAPFIQDDLTLSATQMGLIFSSFSIGYAIFNFLGGVASDR 69 Query: 82 VATRWVLLILAVIWSLAQFPMVGTVSFTTLVICRIILGAGEGPAFSVAAHAIYKWFPDEK 141 + L + V+WSL + F +L+I RI+ G GEGP + + WFP + Sbjct: 70 YGAKLTLFVAMVVWSLFSGAVALAFGFVSLLIIRILFGMGEGPLSATINKMVNNWFPPTQ 129 Query: 142 RTLPTAILSQGSAFGVILAVPALNWIIVNHSWHHAFGALGIVGLIWAVAWFALGKEGPLV 201 R + + G+ G ++ P + I V SW +F + I+GLIWAV WF KE P Sbjct: 130 RASVIGVTNSGTPLGGAISGPIVGMIAVAFSWKVSFVLIMIIGLIWAVLWFKFVKEKPQE 189 Query: 202 S------TSAVTADEPRIPYLKLLTSRTFIGCVVATFGAYWALSLGLTWFTSFIIEGLGF 255 + A T+ +IP L +T + A F + L LTWF S++++ G Sbjct: 190 TIKEAPAIKAETSPGEKIPLTFYLKQKTVLFTAFAFFAYNYILFFFLTWFPSYLVDERGL 249 Query: 256 SQHQAGFVSILPWIFGATIVLLTGWISQLMLTRGFTTRGARGVLGS-----VPLIVGGAI 310 S ++++PWI G + G++S + + T R +GVL S V + A+ Sbjct: 250 SVESMSVITVIPWILGFIGLAAGGFVSDYVYKK--TAR--KGVLFSRKVVLVTCLFSSAV 305 Query: 311 L---AMLPYAPPGGI-MIALLVIGSGLCGSIYVVCPPMLGEFTPVSQRGAIIAIYGALYT 366 L A L G + ++AL V L G+IY ++ + + G++ L Sbjct: 306 LIGFAGLVATTAGAVTLVALSVFFLYLTGAIYWA---VIQDVVDQNNVGSVGGFMHFLAN 362 Query: 367 ISGILAPMVMGNVIQHAAT 385 +GI+ P + G ++ T Sbjct: 363 TAGIIGPALTGFIVDQTGT 381 >RSp0828 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 450 Score = 123 bits (309), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 94/367 (25%), Positives = 176/367 (47%), Gaps = 40/367 (10%) Query: 2 TTQATSKRTSEGTPKGAWQITFLLFLFMVVNFADKIVVGLAGVPIKKEMGLTQEQFGDLG 61 T A S +E T + + I +LF+ +N+AD+ + +AG ++K++G+ G + Sbjct: 7 TVGAQSVPRTERTSRVRFMILAMLFIVTTINYADRATISMAGSAMQKDLGIDAVSLGYIF 66 Query: 62 SSFFLLFSISAIVVGFIVNRVATRWVLLILAVIWSLAQFPMVGTVSFTT-------LVIC 114 S+F + I+ I G++++R +R V ++WSL M GT+ F T + Sbjct: 67 SAFGWAYVIAQIPGGWLLDRFGSRRVYSFSILLWSLFTL-MQGTIGFFTGMAAIVLVFFL 125 Query: 115 RIILGAGEGPAFSVAAHAIYKWFPDEKRTLPTAILSQGSAFGVILAVPALNWIIVNHSWH 174 R ++G E P+F + + WFP +R +AI + ++ P + W++ WH Sbjct: 126 RFMVGVAEAPSFPANSRIVAAWFPANERGTASAIFNSAQYAATVIFAPLMAWLVHAFGWH 185 Query: 175 HAFGALGIVGLIWAVAWFAL---GKEGPLVSTSAVTADE------------------PRI 213 + F +G++G++ A+AW K+ P ++ + + E P + Sbjct: 186 YVFIVMGVIGIVMALAWKRFMHDPKDHPRITRAEIEYIEAGGGLVNMDRAGVAKTEGPDM 245 Query: 214 PYLK-LLTSRTFIGCVVATFGAYWALSLGLTWFTSFIIEGLGFSQHQAGFVSILPWIFGA 272 Y+K LL +R +G +A + +TWF ++++ G S +AGFV+ +P + G Sbjct: 246 GYIKQLLRNRMLMGVYIAQYCINALTYFFITWFPVYLVQARGMSILKAGFVASIPAVCGF 305 Query: 273 TIVLLTGWISQLMLTRGFTTRGARGVLGSVPLIVGGAI---LAMLPYAPPGGIMIALLVI 329 +L G +S +L RG + AR VP+++G + + + Y GI++AL+ + Sbjct: 306 LGGILGGLVSDALLRRGASLSVAR----KVPIVLGMLLSMSMVICNYVDAQGIVVALMAL 361 Query: 330 ---GSGL 333 G GL Sbjct: 362 SFFGKGL 368 >RSp1614 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 448 Score = 123 bits (308), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 95/395 (24%), Positives = 172/395 (43%), Gaps = 23/395 (5%) Query: 4 QATSKRTSEGTPKGAWQITFLLFLFMVVNFADKIVVGLAGVPIKKEMGLTQEQFGDLGSS 63 Q T +R K W + L++ + +N+ D+ V+ A I+KE L+ + G + S+ Sbjct: 2 QDTPQRGQRS--KVRWLVAGLMWAAIAINYIDRTVLSAAAPHIQKEFHLSAVEMGVVMSA 59 Query: 64 FFLLFSISAIVVGFIVNRVATRWVLLILAVIWSLAQFPMVGTVSFTTLVICRIILGAGEG 123 FF +++ + G + +R + VL + WSLA F +LV R+ LG GE Sbjct: 60 FFWSYALLQLPAGILADRFGQKKVLGFAVLWWSLATAVTGLATGFKSLVGLRVALGVGEA 119 Query: 124 PAFSVAAHAIYKWFPDEKRTLPTAILSQGSAFGVILAVPALNWIIVNHSWHHAFGALGIV 183 A+ A +WFP ++R AI GS G +A+P + W++V W F G + Sbjct: 120 GAYPSNAGITSRWFPKQERATVAAIFDSGSKLGSAIALPLIAWLLVTFDWKITFTVAGSL 179 Query: 184 GLIWAVAWFALGKEGPLVSTS---------------AVTADEPRIPYLKLLTSRTFIGCV 228 G++W V W + ++ P A AD P +P+ KLLT R Sbjct: 180 GIVWCVVWALVFRDSPAEHEGVNAAELAHIQKGLPPARGADAPAMPWTKLLTHRNVWAMC 239 Query: 229 VATFGAYWALSLGLTWFTSFIIEGLGFSQHQAGFVSILPWIFGATIVLLTGWISQLMLTR 288 + F + +TW +++++ G + GF++ LP + + GW S + Sbjct: 240 IGFFMINYNSYFFITWLPTYLVKERGMGLMEMGFMASLPLFVSMFVEVFAGWASDRVYAS 299 Query: 289 GFTTRGARGVLGSVPLIVGGAILAMLPYAPPGGIMIALLVI---GSGLCGSIYVVCPPML 345 G + A L V +V + + + +A + + LL I G+ + S P Sbjct: 300 GRLSLTATRKLFLVIGLVMASSIGLAAFAQSAVVAVILLCIAKSGTTVAASQVWALP--- 356 Query: 346 GEFTPVSQRGAIIAIYGALYTISGILAPMVMGNVI 380 + P + + + ++ + G++ P+V G ++ Sbjct: 357 ADVAPGNTVSMVAGLQNSVSNMGGVVGPIVTGAIV 391