BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0006.p (528 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SSO1663 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase,... 213 1e-54 aq_708 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, ... 207 5e-53 mlr7024 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase,... 191 4e-48 MJ0964 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, ... 184 5e-46 PAE2030 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase,... 179 2e-44 >SSO1663 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit Sso Sulfolobus solfataricus Length = 683 Score = 213 bits (541), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 109/305 (35%), Positives = 173/305 (56%), Gaps = 9/305 (2%) Query: 1 MYTIGVDVGGTYTDLVA-TDKTGRTVFAKSPSTPADQSIGVMAGLEELARRLGVTRTAML 59 M +G+D+GG +TD+V ++ G +AK +TP D S GV+ ++E LG T Sbjct: 1 MIRVGIDIGGAFTDVVVYNEENGEISWAKVETTPDDPSNGVLEAIDEAKVNLGYVNT--- 57 Query: 60 AATDRLVHGTTVATNALLERKGARVALLTTEGHRDVVEMREGLKPDRYDLRTPPPEPLVP 119 ++HG T+A N ++ERKGA+V L+TT+G RD++E++ + D Y+ R P P VP Sbjct: 58 -----IIHGQTLAINTIVERKGAKVGLITTKGFRDILEIQRANRRDMYNFRYKKPTPFVP 112 Query: 120 RERRFGVRERLKADGSAAVALDATALGDVIAEVKRSGANSVAVCFLHAYLNPAHELAAAE 179 R R V ER+K++G +L+ + + I ++K ++AV F+++Y+NP HEL E Sbjct: 113 RYLRLEVTERIKSNGDILTSLNENEVVEAIKKLKAENVEAIAVSFINSYVNPIHELKVGE 172 Query: 180 QLAKELPDVSVSRSSDVLPQIKEYERVSTTIVNAYVAPTVRRYLTNLERSLAEAGFAGSL 239 + + P++ V+ S +V + +EYER ST ++NAYV P + +YL+ LE GF G+ Sbjct: 173 IIKRVDPNIIVTLSHEVTREWREYERTSTAVLNAYVMPKMSKYLSKLENEFKNRGFKGNY 232 Query: 240 FVVLSHGGMAPVEEASRLAAGTVLSGPAGGISGSAAGGHGAGDRKEPLPVGQFQPLRDDL 299 F +LS+GGMA + A R T+ SGP G+ G+ G++ G + L Sbjct: 233 FAMLSNGGMATFDYAKRFPIYTLESGPVAGVIGAIKISDILGEKNIIAMDGGSTTTKASL 292 Query: 300 ARRLE 304 R LE Sbjct: 293 VRNLE 297 >aq_708 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit Aae Aquifex aeolicus Length = 660 Score = 207 bits (527), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 131/283 (46%), Positives = 175/283 (61%), Gaps = 19/283 (6%) Query: 4 IGVDVGGTYTDLVATD-KTGRTVFAKSPSTPADQSIGVMAGLEELARRLGVTRTAMLAAT 62 +GVD GGT+TD V D K R + K PSTP++ + V+ GLE+L R A Sbjct: 5 VGVDTGGTFTDFVYWDGKEWRVL--KIPSTPSNPAEAVLKGLEKLRRG---------KAL 53 Query: 63 DRLVHGTTVATNALLERKGARVALLTTEGHRDVVEMREGLKPDRYDLRTPPPEPLVPRER 122 D +VHG+TVATNALLERKGA+ AL+T +G DV+E+ + YDL P+PLVPRE Sbjct: 54 D-VVHGSTVATNALLERKGAKTALITNKGFEDVIEIGRQNRERLYDLYYRKPKPLVPREL 112 Query: 123 RFGVRERLKADGSAAVALDATALGDVIAEVKRSGANSVAVCFLHAYLNPAHELAAAEQLA 182 RFG+ R+ A G ++ L +++ +K G SVAVC LH+Y NP HE E+L Sbjct: 113 RFGLNCRINAKGEVLKPINREELKEILKALKEKGVESVAVCMLHSYANPEHEKEVEEELK 172 Query: 183 KELPDVSVSRSSDVLPQIKEYERVSTTIVNAYVAPTVRRYLTNLERSLAEAGFAGSLFVV 242 K L V VS SS++LP+ +EYER STT++NAYV+P + +YL L+ L E G LF V Sbjct: 173 KNL-SVFVSLSSEILPEFREYERCSTTVINAYVSPKMSKYLYYLKDRLRE----GDLFRV 227 Query: 243 L-SHGGMAPVEEASRLAAGTVLSGPAGGISGSAAGGHGAGDRK 284 + S+GG+ E AS+ A T+LSGPAGG+ G+ G AG K Sbjct: 228 MQSNGGLISPETASKEAVRTILSGPAGGVIGALHLGKLAGFEK 270 >mlr7024 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit Mlo Mesorhizobium loti Length = 692 Score = 191 bits (484), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 113/284 (39%), Positives = 157/284 (55%), Gaps = 5/284 (1%) Query: 2 YTIGVDVGGTYTDLVATD-KTGRTVFAKSPSTPADQSIGVMAGLEELARRLGVTRTAMLA 60 + +GVD+GGT+ D A + +GR K +TP D +M GL LA R G T M Sbjct: 16 WKVGVDIGGTFIDFCALEANSGRVASLKVLTTPEDPGAELMTGLRLLAEREGFDPTRM-- 73 Query: 61 ATDRLVHGTTVATNALLERKGARVALLTTEGHRDVVEMREGLKPDRYDLRTPPPEPLVPR 120 R VHGTTV N +++RKGA +AL T G DV+E+ PD Y L P+PL+ R Sbjct: 74 --TRFVHGTTVGINTIIQRKGAPLALFTNAGFEDVIELARLRMPDMYSLFCSRPDPLISR 131 Query: 121 ERRFGVRERLKADGSAAVALDATALGDVIAEVKRSGANSVAVCFLHAYLNPAHELAAAEQ 180 + FG+ R++ADGS + A D A+ +A K +GA + VCFLHA+ N A E + Sbjct: 132 DMVFGIPTRMRADGSESQAPDMVAVEKAVAAAKANGALGIIVCFLHAWRNAAQEASVKAA 191 Query: 181 LAKELPDVSVSRSSDVLPQIKEYERVSTTIVNAYVAPTVRRYLTNLERSLAEAGFAGSLF 240 +A+ PD+ V S++V P I+EYER ST I+N YV P V YLT LE L + G Sbjct: 192 IARLAPDLFVFSSAEVWPVIREYERSSTAILNGYVHPRVSSYLTALEARLKDRGVPARPM 251 Query: 241 VVLSHGGMAPVEEASRLAAGTVLSGPAGGISGSAAGGHGAGDRK 284 + S+GG+ E R +LSG A G+ G++ AG+ + Sbjct: 252 LTKSNGGLMNAAEGKRACVNMLLSGTASGVIGASWLARQAGENR 295 >MJ0964 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit Mja Methanococcus jannaschii Length = 680 Score = 184 bits (467), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 100/287 (34%), Positives = 151/287 (52%), Gaps = 12/287 (4%) Query: 2 YTIGVDVGGTYTDLVATDKTGRTV-FAKSPSTPADQSIGVMAGLEELARRLGVTRTAMLA 60 Y +G+D+GGT+TDLV D+ + K P+TP +G + +E T Sbjct: 5 YRVGIDIGGTFTDLVYFDEYSKEFHVVKVPTTPKSPDVGAINAIE--------TAKIEFD 56 Query: 61 ATDRLVHGTTVATNALLERKG---ARVALLTTEGHRDVVEMREGLKPDRYDLRTPPPEPL 117 + L+H TT+ TN L ++ ++AL+TT+G +DV+E+ +P YDL P+PL Sbjct: 57 KINILIHATTLGTNMFLGQEHLNPPKIALITTKGFKDVIEIGRQRRPKLYDLFFEKPKPL 116 Query: 118 VPRERRFGVRERLKADGSAAVALDATALGDVIAEVKRSGANSVAVCFLHAYLNPAHELAA 177 + R R+ V ER+ A+G+ L+ L + +K+ V + FLH+Y NP HE A Sbjct: 117 IKRRDRYEVEERIDANGNIITPLNEEELQKIAEIIKKKDYEVVVISFLHSYKNPIHEKKA 176 Query: 178 AEQLAKELPDVSVSRSSDVLPQIKEYERVSTTIVNAYVAPTVRRYLTNLERSLAEAGFAG 237 E + +V V S ++ P+ KEYER STT++NAY+ P V YL N SL GF G Sbjct: 177 REIIKNLCSNVDVITSYEINPEYKEYERTSTTVINAYLKPLVSNYLKNFIDSLKNKGFNG 236 Query: 238 SLFVVLSHGGMAPVEEASRLAAGTVLSGPAGGISGSAAGGHGAGDRK 284 +V+ S GG++ ++ A+ A + SGPA G A D K Sbjct: 237 KFYVMQSSGGISNIKYATERPAAFIESGPAAGAIAVAYFSKILNDNK 283 >PAE2030 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit Pya Pyrobaculum aerophilum Length = 647 Score = 179 bits (453), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 112/274 (40%), Positives = 154/274 (56%), Gaps = 19/274 (6%) Query: 4 IGVDVGGTYTDLVATDKTGRTVFAKSPSTPADQSIGVMAGLEELARRLGVTRTAMLAATD 63 + VDVGGT+TD VA D+ GR + K STP V+ GL + + Sbjct: 3 VAVDVGGTFTDFVALDEEGRLITFKLLSTPKSPEAAVINGLSRVGK------------IG 50 Query: 64 RLVHGTTVATNALLERKG---ARVALLTTEGHRDVVEMREGLKPDRYDLRTPPPEPLVPR 120 ++H +T+ TNALL + G +VAL TT+G RDVVE+ +P YDL P PLVPR Sbjct: 51 EVLHASTIGTNALLGQVGLELPKVALFTTKGFRDVVEIGRQNRPRLYDLYFEKPRPLVPR 110 Query: 121 ERRFGVRERLKADGSAAVALDATALGDVIAEVKRSGANSVAVCFLHAYLNPAHELAAAEQ 180 E RF + ER+ ADG+ +D + +G SVAV FLH+Y+N ++E+ A E Sbjct: 111 ELRFEIEERVLADGTVLKEVDPDEVSRNAKTAADAGVVSVAVSFLHSYINSSNEIKAGEV 170 Query: 181 LAKELPDVSVSRSSDVLPQIKEYERVSTTIVNAYVAPTVRRYLTNLERSLAEAGFAGSLF 240 L + VS+ SS+V P+ +EYER ST +VNA + P V RYL L + + G G L+ Sbjct: 171 LRRYFRYVSL--SSEVAPEPREYERTSTVVVNAALMPLVGRYLEELGKYVESLG--GRLY 226 Query: 241 VVLSHGGMAPVEEASRLAAGTVLSGPAGGISGSA 274 V+ S GG+ VEEA R + SGPAGG+ +A Sbjct: 227 VMSSSGGLVTVEEAVRKPVHLIESGPAGGVVAAA 260