BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0089.p (213 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO3043 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 257 1e-68 SMc02867 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizob... 249 5e-66 RSc0010 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 246 3e-65 PA0426 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 246 3e-65 ECs3332 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia... 244 8e-65 >YPO3043 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1043 Score = 257 bits (656), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 127/201 (63%), Positives = 156/201 (77%), Gaps = 4/201 (1%) Query: 1 MERLADKLPRGFGYEWTGQSLQEKLSGSQAPFLLALSVLVVFLLLAALYESWTIPLAVLL 60 ME+L +LP GFG EWTG S QE+LSGSQAP L A+S+LVVFL LAALYESW+IP +V+L Sbjct: 842 MEKLVSQLPNGFGLEWTGMSYQERLSGSQAPALYAISLLVVFLCLAALYESWSIPFSVML 901 Query: 61 TIPLGILGAVVAATVRGLSNDVYFTVGLITIIGLAAKDAILIIEFAKDLRAQGKPLVEAT 120 +PLG++GAV A +RGL NDVYF VGL+TIIGL+AK+AILI+EFA +L +GK LVEAT Sbjct: 902 VVPLGVIGAVAATWMRGLENDVYFQVGLLTIIGLSAKNAILIVEFANELNNRGKDLVEAT 961 Query: 121 IEACSLRFRPILMTGLAFVCGVLPMAIATGAGGASQQALGTSVMGGMIAVVILALLLVPV 180 +EA R RPILMT LAF+ GVLPMAI+ GAG SQ A+GT VMGGMI+ +LA+ VP+ Sbjct: 962 LEASRQRLRPILMTSLAFIFGVLPMAISQGAGSGSQHAVGTGVMGGMISATVLAIFFVPL 1021 Query: 181 FFVSVQRVLAG----DRETAP 197 FFV V+R G ++E P Sbjct: 1022 FFVLVRRRFPGRIIPNKEINP 1042 >SMc02867 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1048 Score = 249 bits (635), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 121/175 (69%), Positives = 148/175 (84%) Query: 1 MERLADKLPRGFGYEWTGQSLQEKLSGSQAPFLLALSVLVVFLLLAALYESWTIPLAVLL 60 MERL +LP GFGYEWTGQSLQE SGSQAP L+ALS L+VFL LAALYESW+IP++V++ Sbjct: 839 MERLVAELPAGFGYEWTGQSLQEIQSGSQAPLLIALSCLLVFLCLAALYESWSIPVSVIM 898 Query: 61 TIPLGILGAVVAATVRGLSNDVYFTVGLITIIGLAAKDAILIIEFAKDLRAQGKPLVEAT 120 +PLG++GAV+A T+R + NDVYF VGLI IIGL+AK+AILIIEFAK+LR QGK L+++T Sbjct: 899 VVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLIDST 958 Query: 121 IEACSLRFRPILMTGLAFVCGVLPMAIATGAGGASQQALGTSVMGGMIAVVILAL 175 +EA LRFRPILMT LAF GVLP+AIATGA SQ+A+GT VMGGMI+ +LA+ Sbjct: 959 LEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAI 1013 >RSc0010 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1049 Score = 246 bits (628), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 130/194 (67%), Positives = 160/194 (82%) Query: 1 MERLADKLPRGFGYEWTGQSLQEKLSGSQAPFLLALSVLVVFLLLAALYESWTIPLAVLL 60 ME LA +LP G G+EWTGQSLQEK SGSQAP L ALS+L VFL+LAALYESW+IP AV+L Sbjct: 841 MEHLASRLPAGIGFEWTGQSLQEKSSGSQAPALYALSLLAVFLVLAALYESWSIPAAVIL 900 Query: 61 TIPLGILGAVVAATVRGLSNDVYFTVGLITIIGLAAKDAILIIEFAKDLRAQGKPLVEAT 120 +PLG+LGA++ T+R + +DVYF VGLI ++GL+AK+AILIIEFAKDL+AQGK L+EAT Sbjct: 901 VVPLGVLGALLGVTLRFMPDDVYFKVGLIAVVGLSAKNAILIIEFAKDLQAQGKGLIEAT 960 Query: 121 IEACSLRFRPILMTGLAFVCGVLPMAIATGAGGASQQALGTSVMGGMIAVVILALLLVPV 180 +EA LRFRPI+MT AF+ GVLP+AIATGA ASQ+A+GT VMGGMI +LA++LVPV Sbjct: 961 LEAVHLRFRPIIMTSFAFILGVLPLAIATGASSASQRAIGTGVMGGMITATVLAVVLVPV 1020 Query: 181 FFVSVQRVLAGDRE 194 FFV V+R+ G Sbjct: 1021 FFVVVRRIFKGSER 1034 >PA0426 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1046 Score = 246 bits (627), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 115/192 (59%), Positives = 155/192 (80%) Query: 1 MERLADKLPRGFGYEWTGQSLQEKLSGSQAPFLLALSVLVVFLLLAALYESWTIPLAVLL 60 +E + +LP+G GY WTG S +E+LSGSQAP L ALS+LVVFL LAALYESW+IP +V+L Sbjct: 843 VEEIVKQLPKGVGYSWTGLSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPFSVML 902 Query: 61 TIPLGILGAVVAATVRGLSNDVYFTVGLITIIGLAAKDAILIIEFAKDLRAQGKPLVEAT 120 +PLG++GA++A ++RGLSNDV+F VGL+T IGL+AK+AILI+EFAK+L QGK +VEA Sbjct: 903 VVPLGVIGALLATSMRGLSNDVFFQVGLLTTIGLSAKNAILIVEFAKELHEQGKGIVEAA 962 Query: 121 IEACSLRFRPILMTGLAFVCGVLPMAIATGAGGASQQALGTSVMGGMIAVVILALLLVPV 180 IEAC +R RPI+MT LAF+ GV+P+AI+TGAG SQ A+GT V+GGM+ +LA+ VP+ Sbjct: 963 IEACRMRLRPIVMTSLAFILGVVPLAISTGAGSGSQHAIGTGVIGGMVTATVLAIFWVPL 1022 Query: 181 FFVSVQRVLAGD 192 F+V+V + + Sbjct: 1023 FYVAVSTLFKDE 1034 >ECs3332 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia coli O157:H7 Length = 1037 Score = 244 bits (624), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 116/187 (62%), Positives = 147/187 (78%) Query: 1 MERLADKLPRGFGYEWTGQSLQEKLSGSQAPFLLALSVLVVFLLLAALYESWTIPLAVLL 60 ME L +LP GFG EWT S QE+LSG+QAP L A+S+LVVFL LAALYESW++P +V+L Sbjct: 842 MESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVML 901 Query: 61 TIPLGILGAVVAATVRGLSNDVYFTVGLITIIGLAAKDAILIIEFAKDLRAQGKPLVEAT 120 +PLG++GA++A +RGL NDVYF VGL+T+IGL+AK+AILI+EFA ++ +G L EAT Sbjct: 902 VVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEAT 961 Query: 121 IEACSLRFRPILMTGLAFVCGVLPMAIATGAGGASQQALGTSVMGGMIAVVILALLLVPV 180 + AC R RPILMT LAF+ GVLPMA +TGAG Q A+GT VMGGMI+ ILA+ VP+ Sbjct: 962 LHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPL 1021 Query: 181 FFVSVQR 187 FFV V+R Sbjct: 1022 FFVLVRR 1028