BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0046.p (272 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM0212 [GEPR] COG0477 Permeases of the major facilitator superf... 157 2e-38 Cj0339 [GEPR] COG0477 Permeases of the major facilitator superfa... 153 5e-37 ydfJ [GEPR] COG0477 Permeases of the major facilitator superfami... 122 9e-28 ECs2778 [GEPR] COG0477 Permeases of the major facilitator superf... 122 1e-27 ECs2152 [GEPR] COG0477 Permeases of the major facilitator superf... 120 4e-27 >STM0212 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 433 Score = 157 bits (397), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 91/255 (35%), Positives = 147/255 (57%), Gaps = 6/255 (2%) Query: 1 VTMLPREDLMSWGWRLPFLASFLLIVVGIFVRMRITETPVY-----TEAVVARGKVESNP 55 VT LP+E L+SWGWR+PFL S LL++ G+++R R+ ETPV+ +A+ R + E P Sbjct: 173 VTQLPQEALLSWGWRIPFLLSALLVLPGLYMRHRLDETPVFRAFKKQQAINHRQQREERP 232 Query: 56 AMEALRRHPRNFFVVLGARMAENGLGYFFPVFGLSYVITTLGVPKAEALSALMLAFTVEL 115 ++ +R R+ +++ R AE+ + VF +S+ T LG+ L +M + Sbjct: 233 VVKVVREQWRSILLIIILRFAESVPFFLATVFAVSWATTQLGIASLTILYIVMFTCLLAY 292 Query: 116 FAILGFAALSDRIGRRPVYMFGALAGVALAFPFFWMVGTREWIMIALAFILARAVVTAAM 175 + F +SDR G R VY+FGAL A+AFPFFW++ +R I++ + ++L + ++ Sbjct: 293 PMHVLFGIMSDRRGCRQVYIFGALFVAAMAFPFFWLLESRSLILMTMGYVLLINIGHNSL 352 Query: 176 FGPQAAYFAELFPPQRRFAGFAFARELGSLLSGGPAPFVATALVAAYGTWWP-VACYAMF 234 Q ++FA LF P R++G + +LG++++GG PF+A AL A Y W VA Y + Sbjct: 353 NAVQPSFFAGLFHPPVRYSGSSIGAQLGAVVAGGFTPFIAKALSAVYDNSWALVAGYVVL 412 Query: 235 LSACTVIAIWIGPET 249 + + A I PET Sbjct: 413 TALASAFAAKIAPET 427 >Cj0339 [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 453 Score = 153 bits (386), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 85/257 (33%), Positives = 137/257 (53%), Gaps = 6/257 (2%) Query: 4 LPREDLMSWGWRLPFLASFLLIVVGIFVRMRITETPVYTEAVVARGKVESNPAMEALR-- 61 + WGWR+PF+ S L+ + +++R + ETPV+ + K+ N + Sbjct: 190 MDEASFKEWGWRVPFMGSILIALFAVYIRFHVKETPVFEKQKNEMMKLRLNNEKHMKKDE 249 Query: 62 ----RHPRNFFVVLGARMAENGLGYFFPVFGLSYVITTLGVPKAEALSALMLAFTVELFA 117 + R F+ ++G R+ ENG Y F + YV L + K+ A +A+M+A V Sbjct: 250 RSFWQRSRAFWTMVGLRIGENGPSYLAQGFIVGYVTKILLLDKSVATTAVMIASLVGFLV 309 Query: 118 ILGFAALSDRIGRRPVYMFGALAGVALAFPFFWMVGTREWIMIALAFILARAVVTAAMFG 177 I LSD+ GR Y L + AFP F ++ ++ I++ L I+ ++ + +FG Sbjct: 310 IPLAGYLSDKFGRCITYRMFCLLLMIYAFPAFMLLDSKNEIIVILTIIVGMSLASLGIFG 369 Query: 178 PQAAYFAELFPPQRRFAGFAFARELGSLLSGGPAPFVATALVAAYGTWWPVACYAMFLSA 237 QAA+ ELF + R+ AFA+ELGS+LSGG AP VA+AL+A YG+WWP+A Y + + Sbjct: 370 VQAAWGVELFGVKNRYTKMAFAKELGSILSGGTAPMVASALLAYYGSWWPIATYFVLTAG 429 Query: 238 CTVIAIWIGPETYQENI 254 + + PET ++ Sbjct: 430 IGFVTTFFAPETRGRDL 446 >ydfJ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 427 Score = 122 bits (306), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 80/265 (30%), Positives = 136/265 (51%), Gaps = 9/265 (3%) Query: 3 MLPREDLMSWGWRLPFLASFLLIVVGIFVRMRITETPVYTEAVVARGKVESNPAMEALRR 62 +L +E+L++WGWR+PFLAS +++V I++RM + E+PV+ E V + + PA Sbjct: 152 ILSKEELLAWGWRIPFLASVVVMVFAIWLRMNLKESPVF-EKVNDSNQPTAKPAPAGSMF 210 Query: 63 HPRNFFVVLGARMAENGLGYFFPVFGLSYVITTLGVPKAEALSALMLAFTVELFAILGFA 122 ++F++ G R + G F Y++ TL KA ALM++ + I Sbjct: 211 QSKSFWLATGLRFGQAGNSGLIQTFLAGYLVQTLLFNKAIPTDALMISSILGFMTIPFLG 270 Query: 123 ALSDRIGRRPVYMFGALAGVALAFPFFWMVGTREW----IMIALAFILARAVVTAAMFGP 178 LSD+IGRR Y+ + + LA+P ++ + + IM+AL I AV+ +F Sbjct: 271 WLSDKIGRRIPYIIMNTSAIVLAWPMLSIIVDKSYAPSTIMVALIVIHNCAVL--GLFAL 328 Query: 179 QAAYFAELFPPQRRFAGFAFARELGSLLSGGPAPFVATALVAAYGTWWPVACYAMFLSAC 238 + AE+F + RF A ++E+G L++ G P +A +W+P+A M S Sbjct: 329 ENITMAEMFGCKNRFTRMAISKEIGGLIASGFGPILAGIFCTMTESWYPIAIMIMAYSVI 388 Query: 239 TVIAIWIGPETYQENIAA--DASEQ 261 +I+ PE +++A DA+E Sbjct: 389 GLISALKMPEVKDRDLSALEDAAED 413 >ECs2778 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 438 Score = 122 bits (305), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 77/243 (31%), Positives = 121/243 (49%), Gaps = 4/243 (1%) Query: 3 MLPREDLMSWGWRLPFLASFLLIVVGIFVRMRITETPVYTEAVVARGKVESN-PAMEALR 61 M E +SWGWR+PFL S +L++ ++VR + E+ + + + + P +EAL Sbjct: 187 MTTDEQFLSWGWRIPFLFSIVLVLGALWVRNGMEESAEFEQQQYNQAAAKKRIPVIEALL 246 Query: 62 RHPRNFFVVLGARMAENGLGYFFPVFGLSYVITTLGVPKAEALSALMLAFTVELFAILGF 121 RHP F ++ R+ E Y F L+Y +G+P+ L+ +L + I F Sbjct: 247 RHPGAFLKIIALRLCELLTMYIVTAFALNYSTQNMGLPRELFLNIGLLVGGLSCLTIPCF 306 Query: 122 AALSDRIGRRPVYMFGALAGVALAFPFFWMVGTREWIMIALAFILARAVVTAAMFGPQAA 181 A L+DR GRR VY+ GAL G AFPFF + + I I+ + + Q Sbjct: 307 AWLADRFGRRRVYITGALIGTLSAFPFFMALEAQSIFWIVFFSIMLANIAHDMVVCVQQP 366 Query: 182 YFAELFPPQRRFAGFAFARELGSLLSGGPAPFVATALVAAY-GTWWPVACYAMFLSACTV 240 F E+F R++G ++ S++ GG PF+A AL+ + G W VA Y L+ C + Sbjct: 367 MFTEMFGASYRYSGAGVGYQVASVVGGGFTPFIAAALITYFAGNWHSVAIY--LLAGCLI 424 Query: 241 IAI 243 A+ Sbjct: 425 SAM 427 >ECs2152 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 427 Score = 120 bits (301), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 80/265 (30%), Positives = 135/265 (50%), Gaps = 9/265 (3%) Query: 3 MLPREDLMSWGWRLPFLASFLLIVVGIFVRMRITETPVYTEAVVARGKVESNPAMEALRR 62 +L +E+L++WGWR+PFLAS +++V I++RM + E+PV+ E V + + PA Sbjct: 152 ILSKEELLAWGWRIPFLASVVVMVFAIWLRMNLKESPVF-EKVNDSNQPTAKPAPAGSIF 210 Query: 63 HPRNFFVVLGARMAENGLGYFFPVFGLSYVITTLGVPKAEALSALMLAFTVELFAILGFA 122 ++F++ G R + G F Y++ TL KA ALM++ I Sbjct: 211 QSKSFWLATGLRFGQAGNSGLIQTFLAGYLVQTLLFNKAIPTDALMISSIPGFMTIPFLG 270 Query: 123 ALSDRIGRRPVYMFGALAGVALAFPFFWMVGTREW----IMIALAFILARAVVTAAMFGP 178 LSD+IGRR Y+ + + LA+P ++ + + IM+AL I AV+ +F Sbjct: 271 WLSDKIGRRIPYIIMNTSAIVLAWPMLSIIVDKSYAPSTIMVALIVIHNCAVL--GLFAL 328 Query: 179 QAAYFAELFPPQRRFAGFAFARELGSLLSGGPAPFVATALVAAYGTWWPVACYAMFLSAC 238 + AE+F + RF A ++E+G L++ G P +A +W+P+A M S Sbjct: 329 ENITMAEMFGCKNRFTRMAISKEIGGLIASGFGPILAGIFCTMTESWYPIAIMIMAYSVI 388 Query: 239 TVIAIWIGPETYQENIAA--DASEQ 261 +I+ PE +++A DA+E Sbjct: 389 GLISALKMPEVKDRDLSALEDAAED 413