BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0002.p (424 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr4319 [J] COG0621 2-methylthioadenine synthetase Mlo Mesorhizo... 530 e-150 BMEI0132 [J] COG0621 2-methylthioadenine synthetase Bme Brucella... 515 e-146 AGc4885 [J] COG0621 2-methylthioadenine synthetase Atu Agrobacte... 500 e-141 CC3684 [J] COG0621 2-methylthioadenine synthetase Ccr Caulobacte... 488 e-137 SMc03855 [J] COG0621 2-methylthioadenine synthetase Sme Sinorhiz... 486 e-137 >mlr4319 [J] COG0621 2-methylthioadenine synthetase Mlo Mesorhizobium loti Length = 446 Score = 530 bits (1366), Expect = e-150, Method: Compositional matrix adjust. Identities = 268/423 (63%), Positives = 321/423 (75%), Gaps = 10/423 (2%) Query: 3 IDVVTFGCRLNAFESEVIRREAEQAGLT----DAIVINSCAVTNEAVAQARQSIRKLKRE 58 IDVVTFGCRLN +ESEV+RREAE AGL A++ N+CAVT EAV QARQ+IRK +R+ Sbjct: 22 IDVVTFGCRLNTYESEVMRREAESAGLGALQGGAVIFNTCAVTGEAVRQARQAIRKARRD 81 Query: 59 RPQARIVVTGCAAQTQSQMFADMAEVDRVVGNDEKMRGDAWRATRSAFEAPFGIDASEKV 118 P ARI+VTGCAAQT+ + FA M EVD V+GN+EK++ +++RA FG++ +EK Sbjct: 82 NPGARIIVTGCAAQTEPEKFAAMDEVDLVLGNEEKLKANSYRALPD-----FGVNDTEKA 136 Query: 119 AVADIMAVTEMAPHLLDGFERGLPRVFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVD 178 V DI +V E A H++D E G R FVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVV+ Sbjct: 137 RVNDIFSVRETAGHMVDAIE-GRARAFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVE 195 Query: 179 QVRALVERGHAEIVLTGVDLTSYGADLPGAPKLGQLTRQILRHVPELKRLRISSIDSIEA 238 QV+ L G+AEIVLTGVD+TS+GADLPGAPKLG+L + IL+ VP++KRLR+SSIDSIEA Sbjct: 196 QVKRLAGNGYAEIVLTGVDMTSFGADLPGAPKLGRLVKTILKQVPDVKRLRLSSIDSIEA 255 Query: 239 DRDLLDVIADDARLMPHLHLSLQSGDDMILKRMKRRHSRRDAIDFCAQVRRLRPDIALGA 298 D DLLD IA + RLMPHLHLSLQSGDDMILKRMKRRH R +I FC VR+LRP+I GA Sbjct: 256 DDDLLDAIATEPRLMPHLHLSLQSGDDMILKRMKRRHLRDQSIRFCEDVRKLRPEIVFGA 315 Query: 299 DIIAGFPTESEEMFARSLDLVEECDLTFLHVFPYSRRPGTPAARMPQVEGGAIKERARQL 358 DIIAGFPTE++ MF S+ +VEEC LT LHVFP+S R GTPAARMPQV +K+RA +L Sbjct: 316 DIIAGFPTETDAMFENSIKIVEECGLTHLHVFPFSPREGTPAARMPQVRREVVKQRAARL 375 Query: 359 RTAGEAALLRRLDAEVGATREVLIESGTQGRTEHFLPVAIDDDVPGAVRRLVVTGHDGAR 418 R AGEAA R L + G + +LIE GRTE F A+ PG + +TGHDGAR Sbjct: 376 RAAGEAAYRRHLSSLPGTRQSILIERDGLGRTEGFTLAALGTGAPGEIVEATITGHDGAR 435 Query: 419 LVA 421 L A Sbjct: 436 LNA 438 >BMEI0132 [J] COG0621 2-methylthioadenine synthetase Bme Brucella melitensis Length = 447 Score = 515 bits (1326), Expect = e-146, Method: Compositional matrix adjust. Identities = 259/426 (60%), Positives = 316/426 (74%), Gaps = 10/426 (2%) Query: 1 MGIDVVTFGCRLNAFESEVIRREAEQAGLTD----AIVINSCAVTNEAVAQARQSIRKLK 56 M +++VTFGCRLN +ESEV++REA+ AGL AI+ N+CAVT EAV QARQ+IRK + Sbjct: 21 MSVEIVTFGCRLNTYESEVMKREADAAGLGTLKDGAIIFNTCAVTAEAVRQARQAIRKAR 80 Query: 57 RERPQARIVVTGCAAQTQSQMFADMAEVDRVVGNDEKMRGDAWRATRSAFEAPFGIDASE 116 RE P ARI+VTGCAAQT++ FA M EVD V+GN+EK++ +++R FG++ E Sbjct: 81 RENPDARIIVTGCAAQTEADNFAAMGEVDLVLGNEEKLKSNSYRML-----PDFGVNQFE 135 Query: 117 KVAVADIMAVTEMAPHLLDGFERGLPRVFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAV 176 KV V DIM V E A H++D E G R FVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAV Sbjct: 136 KVRVNDIMEVRETASHMVDAIE-GRARAFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAV 194 Query: 177 VDQVRALVERGHAEIVLTGVDLTSYGADLPGAPKLGQLTRQILRHVPELKRLRISSIDSI 236 VDQV+ LV G+AE+VLTGVD+TSYG DLP +LG+L + +L VP+L+RLR+SSIDSI Sbjct: 195 VDQVKRLVGNGYAEVVLTGVDMTSYGPDLPSNLRLGKLVKTVLAQVPDLQRLRLSSIDSI 254 Query: 237 EADRDLLDVIADDARLMPHLHLSLQSGDDMILKRMKRRHSRRDAIDFCAQVRRLRPDIAL 296 EAD DL++ IA + RLMPHLHLSLQ+GDDMILKRMKRRH R D+I FC R LRPDI Sbjct: 255 EADEDLMEAIASEKRLMPHLHLSLQAGDDMILKRMKRRHLRDDSIRFCQTARALRPDIVF 314 Query: 297 GADIIAGFPTESEEMFARSLDLVEECDLTFLHVFPYSRRPGTPAARMPQVEGGAIKERAR 356 GADIIAGFPTE+EEMF SL +VEEC LT LHVFPYS R GTPAARMPQV +KERA Sbjct: 315 GADIIAGFPTETEEMFQNSLKIVEECGLTHLHVFPYSPREGTPAARMPQVRREIVKERAA 374 Query: 357 QLRTAGEAALLRRLDAEVGATREVLIESGTQGRTEHFLPVAIDDDVPGAVRRLVVTGHDG 416 +LR G+ A + L+A G + +L+E RTE F A+D G + +VTGHDG Sbjct: 375 RLRAEGDRAYEKHLNALHGTRQRLLVEKEGVARTEGFTLAAVDQGNAGEIIERIVTGHDG 434 Query: 417 ARLVAQ 422 +L+ + Sbjct: 435 EKLLTR 440 >AGc4885 [J] COG0621 2-methylthioadenine synthetase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 448 Score = 500 bits (1288), Expect = e-141, Method: Compositional matrix adjust. Identities = 251/418 (60%), Positives = 313/418 (74%), Gaps = 6/418 (1%) Query: 2 GIDVVTFGCRLNAFESEVIRREAEQAGLTDAIVINSCAVTNEAVAQARQSIRKLKRERPQ 61 G++V+TFGCRLN +ESEV+R EAE+AGL +A+++N+CAVT EAV QARQ+IR+ +R+ P Sbjct: 27 GVEVITFGCRLNTYESEVMRAEAEKAGLNNAVLVNTCAVTGEAVRQARQAIRRARRDNPH 86 Query: 62 ARIVVTGCAAQTQSQMFADMAEVDRVVGNDEKMRGDAWRATRSAFEAPFGIDASEKVAVA 121 ARI+VTGCAAQT+ Q FADM EVD V+GN+EK++ ++RA FG+ A EK+ V Sbjct: 87 ARIIVTGCAAQTEKQTFADMPEVDAVLGNEEKLKSASYRALPD-----FGVSAEEKLRVN 141 Query: 122 DIMAVTEMAPHLLDGFERGLPRVFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQVR 181 DIM++ AP ++ + G R F+QVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQ R Sbjct: 142 DIMSIKATAPQMVKHID-GHVRAFIQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQAR 200 Query: 182 ALVERGHAEIVLTGVDLTSYGADLPGAPKLGQLTRQILRHVPELKRLRISSIDSIEADRD 241 L E G+ EIVLTGVD TSYGADLPG P LG L + +L+ VP++ RLR+SSIDSIEAD Sbjct: 201 RLTESGYCEIVLTGVDATSYGADLPGEPSLGYLAKTLLKQVPDIIRLRLSSIDSIEADHH 260 Query: 242 LLDVIADDARLMPHLHLSLQSGDDMILKRMKRRHSRRDAIDFCAQVRRLRPDIALGADII 301 L+D+IAD+ R MPHLHLSLQ GDDMILKRMKRRH R DAI FC +VR LRPDIA GAD+I Sbjct: 261 LMDLIADEPRFMPHLHLSLQHGDDMILKRMKRRHLRADAIRFCNEVRSLRPDIAFGADMI 320 Query: 302 AGFPTESEEMFARSLDLVEECDLTFLHVFPYSRRPGTPAARMPQVEGGAIKERARQLRTA 361 AGFPTE+EEM + L EEC ++ LHVFPYS R GTPA RMPQ++ +KERA +LR Sbjct: 321 AGFPTETEEMLENAATLAEECGISSLHVFPYSPREGTPAVRMPQLDRALVKERAGRLRAR 380 Query: 362 GEAALLRRLDAEVGATREVLIESGTQGRTEHFLPVAIDDDVPGAVRRLVVTGHDGARL 419 GEA L VG+ + VL+E+ T++F VA D P + ++ +TGH+G L Sbjct: 381 GEALKQAHLQNMVGSVQTVLVENSGFAHTDNFTLVAAPDLAPRTLAQVAITGHNGKHL 438 >CC3684 [J] COG0621 2-methylthioadenine synthetase Ccr Caulobacter vibrioides Length = 443 Score = 488 bits (1256), Expect = e-137, Method: Compositional matrix adjust. Identities = 249/422 (59%), Positives = 302/422 (71%), Gaps = 14/422 (3%) Query: 2 GIDVVTFGCRLNAFESEVIRREAEQAGLTDAIVINSCAVTNEAVAQARQSIRKLKRERPQ 61 G+DVVTFGCRLNA+ESE +R A GL+DA+V N+CAVTNEAV QARQ+IRK +RERP Sbjct: 32 GVDVVTFGCRLNAYESEAMRARASADGLSDAVVFNTCAVTNEAVRQARQAIRKARRERPG 91 Query: 62 ARIVVTGCAAQTQSQMFADMAEVDRVVGNDEKMRGDAWRATRSAFEAPFGIDASEKVAVA 121 ARI+VTGCAAQ FA M EVD V+GN EK A D S +V V Sbjct: 92 ARIIVTGCAAQVDPAAFAAMPEVDLVLGNAEKAAPGAL------------TDTSTRVRVN 139 Query: 122 DIMAVTEMAPHLLDGFERGLPRVFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQVR 181 DIM++ E A HL+DG + R +V+VQNGCDHRCTFCIIPYGRGNSRS P G VV+QVR Sbjct: 140 DIMSIKETAGHLIDGL-KDRARAYVEVQNGCDHRCTFCIIPYGRGNSRSAPAGEVVEQVR 198 Query: 182 ALVERGHAEIVLTGVDLTSYGADLPGAPKLGQLTRQILRHVPELKRLRISSIDSIEADRD 241 L G+ E+VLTGVD+TS+GADLPG P LGQL +ILR VP+L RLR+SSID+ E D D Sbjct: 199 KLAAEGYREVVLTGVDVTSWGADLPGQPTLGQLVGRILRMVPDLPRLRLSSIDAAEIDPD 258 Query: 242 LLDVIADDARLMPHLHLSLQSGDDMILKRMKRRHSRRDAIDFCAQVRRLRPDIALGADII 301 L ++ + RLMP+LHLSLQ+GD++ILKRMKRRHSR DA+ A+VRR+RPD A GAD+I Sbjct: 259 LFKLLETEPRLMPYLHLSLQAGDNLILKRMKRRHSREDALKLVAEVRRVRPDTAFGADLI 318 Query: 302 AGFPTESEEMFARSLDLVEECDLTFLHVFPYSRRPGTPAARMPQVEGGAIKERARQLRTA 361 AGFPTE++E F +L LVEE L FLHVFPYS RPGTPAARMP V+G IK+RAR+LR A Sbjct: 319 AGFPTETDEAFENTLKLVEEAGLAFLHVFPYSARPGTPAARMPPVKGPVIKDRARRLREA 378 Query: 362 GEAALLRRLDAEVGATREVLIESGTQGRTEHFLPVAIDDDVP-GAVRRLVVTGHDGARLV 420 G+ L R L +VG L+E R E F +A + P G + VTGHDG+R++ Sbjct: 379 GQRGLERHLQRQVGRVLSGLVERDGVARAEDFTEIAFAGEAPSGQILAFRVTGHDGSRVI 438 Query: 421 AQ 422 A+ Sbjct: 439 AE 440 >SMc03855 [J] COG0621 2-methylthioadenine synthetase Sme Sinorhizobium meliloti Length = 424 Score = 486 bits (1250), Expect = e-137, Method: Compositional matrix adjust. Identities = 246/423 (58%), Positives = 314/423 (74%), Gaps = 6/423 (1%) Query: 2 GIDVVTFGCRLNAFESEVIRREAEQAGLTDAIVINSCAVTNEAVAQARQSIRKLKRERPQ 61 G++V+TFGCRLN +ESEV+R EAE+AGL +A+++N+CAVT EAV QARQ+IR+ +RE P Sbjct: 3 GVEVITFGCRLNTYESEVMRAEAEKAGLNNAVLVNTCAVTAEAVRQARQAIRRARRENPH 62 Query: 62 ARIVVTGCAAQTQSQMFADMAEVDRVVGNDEKMRGDAWRATRSAFEAPFGIDASEKVAVA 121 ARI+VTGCAAQT+ + FA+MAEVD V+GN+EK+ ++R+ FG+ A EK+ V Sbjct: 63 ARIIVTGCAAQTEKETFAEMAEVDAVLGNEEKLASVSYRSLPD-----FGVSAEEKLRVN 117 Query: 122 DIMAVTEMAPHLLDGFERGLPRVFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQVR 181 DIM+V AP ++ + G R F+QVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQ R Sbjct: 118 DIMSVRATAPQMVKHID-GHVRAFIQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQAR 176 Query: 182 ALVERGHAEIVLTGVDLTSYGADLPGAPKLGQLTRQILRHVPELKRLRISSIDSIEADRD 241 L E G+ EIVLTGVD TSYGADLPG P LG L + +L+ VPE+ RLR+SSIDSIEAD Sbjct: 177 RLAESGYREIVLTGVDATSYGADLPGTPTLGLLAKTLLKQVPEILRLRLSSIDSIEADGH 236 Query: 242 LLDVIADDARLMPHLHLSLQSGDDMILKRMKRRHSRRDAIDFCAQVRRLRPDIALGADII 301 LLD+IA++ R MPHLHLSLQ GDD+ILKRMKRRHS DA FC +VRRLRP I+LGAD+I Sbjct: 237 LLDLIAEEPRFMPHLHLSLQHGDDLILKRMKRRHSSADARAFCDEVRRLRPGISLGADMI 296 Query: 302 AGFPTESEEMFARSLDLVEECDLTFLHVFPYSRRPGTPAARMPQVEGGAIKERARQLRTA 361 AGFPTE+E MF ++ L E+C + LHVFPYS RPGTPAARMPQ++ +KERA +LR Sbjct: 297 AGFPTETEPMFENAMRLAEDCGIAHLHVFPYSPRPGTPAARMPQLDRALVKERAARLRAK 356 Query: 362 GEAALLRRLDAEVGATREVLIESGTQGRTEHFLPVAIDDDVPGAVRRLVVTGHDGARLVA 421 G L+ +G+++ +L+E TE+F V P ++ + +TGH+G L Sbjct: 357 GAELHAGHLEGMIGSSQTILVEMNGLAHTENFTLVDAAGLEPRSLVAVGITGHNGKHLTI 416 Query: 422 QDR 424 + + Sbjct: 417 ERK 419