BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0029.p (277 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl807 [IQR] COG1028 Dehydrogenases with different specificities... 278 7e-75 SMb21111 [IQR] COG1028 Dehydrogenases with different specificiti... 268 7e-72 BMEI1709 [IQR] COG1028 Dehydrogenases with different specificiti... 265 9e-71 mll4781 [IQR] COG1028 Dehydrogenases with different specificitie... 261 1e-69 YPO1565 [IQR] COG1028 Dehydrogenases with different specificitie... 260 3e-69 >AGl807 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 264 Score = 278 bits (712), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 140/245 (57%), Positives = 171/245 (69%), Gaps = 5/245 (2%) Query: 34 MSDRLKGKRAFVTAAAVGIGRACALAFAREGATVFATDIDEGKLALLKQEGVAEVAKLDV 93 M G+ +TAA GIGRA A F GA V ATDI+E L+ LK AE L+V Sbjct: 22 MVQDFNGRTVVITAAGQGIGRATAERFISLGARVIATDINEQALSTLKG---AETRVLNV 78 Query: 94 RDTAAVEAIAKRAGKTDILLNAAGFVHHGTALECSDDDWDFSFDLNVKSMHRTTRAFLPG 153 D VE A G D+L N AGFVH GT L+C + DWDFSFDLN K+M+RT RAFLPG Sbjct: 79 LDGDGVEDFAADIGHADVLFNCAGFVHSGTILDCEEKDWDFSFDLNAKAMYRTCRAFLPG 138 Query: 154 MLAQGGGAIVNIASAAGAVKAAPNRYVYSATKAAVAALTRSVAADFITKGIRCNCICPGT 213 ML +G GAIVN++S A +VK PNR+ Y+A+KAAV LT+++AADF+TKGIRCN ICPGT Sbjct: 139 MLEKGKGAIVNMSSVASSVKGVPNRFAYTASKAAVVGLTKAIAADFVTKGIRCNAICPGT 198 Query: 214 IETPSMLERAAAAGPQGREM--FVARQPMGRLGTAEEIAALAVYLASDESSFTTGVAHVI 271 +++PS+ +R A G + + F+ARQPMGR+ T EEIAAL YLASDE+ FTTG HVI Sbjct: 199 VDSPSLHDRLRATGNYEQALADFIARQPMGRIATPEEIAALVTYLASDEAGFTTGQIHVI 258 Query: 272 DGGWT 276 DGGWT Sbjct: 259 DGGWT 263 >SMb21111 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 244 Score = 268 bits (686), Expect = 7e-72, Method: Compositional matrix adjust. Identities = 139/246 (56%), Positives = 172/246 (69%), Gaps = 4/246 (1%) Query: 34 MSDRLKGKRAFVTAAAVGIGRACALAFAREGATVFATDIDEGKLALLKQEGVAEVAKLDV 93 M+ L GK VTAAA GIGRA ALAFA+ GA V ATDI+ + L+ E +LDV Sbjct: 1 MTANLAGKVVLVTAAAQGIGRATALAFAKAGAKVHATDINADAVGSLEGEAGISTHRLDV 60 Query: 94 RDTAAVEAIAKRAGKTDILLNAAGFVHHGTALECSDDDWDFSFDLNVKSMHRTTRAFLPG 153 DTAAVEA+ G D+L N AGFVH G+ L D+D DF+FDLNVKSM RT RA LPG Sbjct: 61 LDTAAVEALVAEIGAVDVLFNCAGFVHAGSVLTMKDEDLDFAFDLNVKSMIRTIRAVLPG 120 Query: 154 MLAQGGGAIVNIASAAGAVKAAPNRYVYSATKAAVAALTRSVAADFITKGIRCNCICPGT 213 M+A+ G+IVN+AS A ++K PNR+ Y TKAAV LT++VAAD++ GIRCN ICPGT Sbjct: 121 MIARKDGSIVNMASVASSIKGVPNRFAYGVTKAAVIGLTKAVAADYVGDGIRCNAICPGT 180 Query: 214 IETPSMLERAAAAG--PQGREMFVARQPMGRLGTAEEIAALAVYLASDESSFTTGVAHVI 271 +E+PS+ R A G R F++RQPMGRLGT EEIA LAVYLA +++T+G A+ I Sbjct: 181 VESPSLESRMRAQGDYETARAAFISRQPMGRLGTPEEIADLAVYLAG--ATYTSGQAYAI 238 Query: 272 DGGWTL 277 DGGWT+ Sbjct: 239 DGGWTI 244 >BMEI1709 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bme Brucella melitensis Length = 244 Score = 265 bits (677), Expect = 9e-71, Method: Compositional matrix adjust. Identities = 139/248 (56%), Positives = 178/248 (71%), Gaps = 8/248 (3%) Query: 34 MSDRLKGKRAFVTAAAVGIGRACALAFAREGATVFATDIDEGKLALLKQEGVAEVA--KL 91 M+ RL GK A VTAA GIG+A ALAF GA V+ATDI+ LA K EG+A + +L Sbjct: 1 MTIRLDGKTALVTAAGQGIGQASALAFVEAGAKVYATDINADALA--KLEGIAGIVTRRL 58 Query: 92 DVRDTAAVEAIAKRAGKTDILLNAAGFVHHGTALECSDDDWDFSFDLNVKSMHRTTRAFL 151 DV D AAV+A+ G+ DIL N AGFVH+GT LE D++ DF+ +LNV+SM RT RA L Sbjct: 59 DVLDDAAVKALVAEIGQIDILFNCAGFVHNGTILEMKDEELDFAVNLNVRSMIRTIRAVL 118 Query: 152 PGMLAQGGGAIVNIASAAGAVKAAPNRYVYSATKAAVAALTRSVAADFITKGIRCNCICP 211 PGML + GAI+N+AS A +VK NR+VY TKAAV LT++VAAD+++KGIRCN ICP Sbjct: 119 PGMLERKDGAIINMASVASSVKGVSNRFVYGLTKAAVIGLTKAVAADYVSKGIRCNAICP 178 Query: 212 GTIETPSMLERAAAAGPQ--GREMFVARQPMGRLGTAEEIAALAVYLASDESSFTTGVAH 269 GT+E+PS+ +R A G R F+ARQP+GR+G EEIA LAVYLA +++TTG A+ Sbjct: 179 GTVESPSLQDRLRAQGDYEAARAAFIARQPIGRIGQPEEIADLAVYLAG--ATYTTGQAY 236 Query: 270 VIDGGWTL 277 IDGGW++ Sbjct: 237 NIDGGWSI 244 >mll4781 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 243 Score = 261 bits (667), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 137/246 (55%), Positives = 174/246 (70%), Gaps = 5/246 (2%) Query: 34 MSDRLKGKRAFVTAAAVGIGRACALAFAREGATVFATDIDEGKLALLKQEGVAEVAKLDV 93 M+D L GK +TAAA GIG+A ALAFA+ GATV ATDI+E LA L + + KLDV Sbjct: 1 MAD-LAGKVVVITAAAQGIGKASALAFAKTGATVHATDINETLLAELAKTPGIKTRKLDV 59 Query: 94 RDTAAVEAIAKRAGKTDILLNAAGFVHHGTALECSDDDWDFSFDLNVKSMHRTTRAFLPG 153 + AV G+ D+L N AGFVH G+ LE D D DF+F+LNV++M RT RA LPG Sbjct: 60 LNDEAVNTTFAEIGRVDVLFNCAGFVHSGSILEMKDGDLDFAFNLNVRAMIRTIRAVLPG 119 Query: 154 MLAQGGGAIVNIASAAGAVKAAPNRYVYSATKAAVAALTRSVAADFITKGIRCNCICPGT 213 ML +G G+IVN++S AGA K PNR+ Y TKAAV LT+++AAD++ KGIRCN ICPGT Sbjct: 120 MLERGDGSIVNMSSVAGAGKGVPNRFAYGVTKAAVIGLTKAIAADYVGKGIRCNAICPGT 179 Query: 214 IETPSMLERAAAAGPQ--GREMFVARQPMGRLGTAEEIAALAVYLASDESSFTTGVAHVI 271 +E+PS+ +R A G R F+ARQPMGRLGT EEIA LAVYLA +++T+G A+ I Sbjct: 180 VESPSLQDRMHAQGDYEAARAAFIARQPMGRLGTPEEIADLAVYLAG--ATYTSGQAYNI 237 Query: 272 DGGWTL 277 DGGW++ Sbjct: 238 DGGWSI 243 >YPO1565 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ype Yersinia pestis Length = 246 Score = 260 bits (664), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 131/247 (53%), Positives = 172/247 (69%), Gaps = 10/247 (4%) Query: 37 RLKGKRAFVTAAAVGIGRACALAFAREGATVFATDIDEGKLALLKQEGVAEVAKLDVRDT 96 LKGK+A VTAA GIG A FAR+GA V A+DI+ L+ + G+ V+ LDV DT Sbjct: 2 NLKGKKALVTAAGQGIGFNTATLFARKGAEVIASDINIAALSNIP--GITAVS-LDVTDT 58 Query: 97 AAVEAIAKRAGKTDILLNAAGFVHHGTALECSDDDWDFSFDLNVKSMHRTTRAFLPGMLA 156 A+ +A+ G D+L N AG VH G L CS+ +W F+ DLNV +M RAFLPGM+A Sbjct: 59 LAINDVAQAIGPIDVLFNCAGVVHSGDILTCSEQEWQFALDLNVTAMFHMIRAFLPGMIA 118 Query: 157 QGGGAIVNIASAAGAVKAAPNRYVYSATKAAVAALTRSVAADFITKGIRCNCICPGTIET 216 G+I+N++S A ++K PNR+ YS +KAAV LTRSVAAD++T+GIRCN ICPGT+E+ Sbjct: 119 CQQGSIINMSSVASSIKGVPNRFAYSTSKAAVIGLTRSVAADYVTQGIRCNAICPGTVES 178 Query: 217 PSMLER-AAAAGPQGR------EMFVARQPMGRLGTAEEIAALAVYLASDESSFTTGVAH 269 PS+ +R A A +GR + F ARQP+GR+G AEEIA LA+YLASD S++TTG H Sbjct: 179 PSLRQRIAVQAHAEGRSEADVFQAFAARQPIGRIGKAEEIAQLALYLASDASAYTTGTIH 238 Query: 270 VIDGGWT 276 +IDGGW+ Sbjct: 239 IIDGGWS 245