BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0039.p (430 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc02836 [V] COG1132 ABC-type multidrug transport system, ATPase... 298 2e-80 mll5362 [V] COG1132 ABC-type multidrug transport system, ATPase ... 293 5e-79 SMb20813 [V] COG1132 ABC-type multidrug transport system, ATPase... 291 1e-78 BMEII0250 [V] COG1132 ABC-type multidrug transport system, ATPas... 265 1e-70 AGl552 [V] COG1132 ABC-type multidrug transport system, ATPase a... 260 6e-69 >SMc02836 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Sme Sinorhizobium meliloti Length = 601 Score = 298 bits (762), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 158/435 (36%), Positives = 247/435 (56%), Gaps = 27/435 (6%) Query: 18 LIRRLVMEQGITYWRRYLTAFALMAVAAGSTAGATYVLGQVINQAYVDKNIPGIAMFAGI 77 +++R++ E G + R Y A A + V A +T +++ V+N+A+ ++ + + G Sbjct: 19 ILKRVIAENGRDHIRGYAFAIACLVVVAATTGFTAWIMEAVVNEAFANRRADIVLLICGA 78 Query: 78 TVVLLFIKGVATYGHMVILNKISNAILASNQRQLFAKLMSESIGFFSQRHSSEFLARLTA 137 ++G+ATYG V L+KI N I+A QR+L+A LM+ S+G+F + S++ A+++ Sbjct: 79 IFAAFVLRGLATYGQAVALSKIGNNIVARYQRRLYAHLMALSVGYFHEHRSAQLAAKVSQ 138 Query: 138 GAKSITDVLNMLVNAIGRDFLMLISMVAVMVWQDPLMSFIGLVAVPPAMLMLRRLVKRIK 197 I DVLNM V +I RD L LI +V VM +D L+S I PP +L LR + +R++ Sbjct: 139 NVSGIRDVLNMTVTSIARDLLTLIGLVVVMFSKDWLLSLIVFFVAPPLLLGLRYISRRLR 198 Query: 198 GLAYNQFTGTADIMETMQESLQGIRTVKAFTLEGTMQQRIDEHIATVESNANKMARVANR 257 + ++ MQE++QGI VKAFT+E ++++++ I E+ AN++AR++ R Sbjct: 199 LATREAVEVNSRVLGAMQETIQGITIVKAFTMENELRRKVESIIDRAENRANRIARLSER 258 Query: 258 SNPLMEMLGGFAVAGCLMYGGYSVVALGSTPGQFFTFLTAFLMATEPAKRLARLNIDLNS 317 + P+ E G A++ L Y + + PG FF F+TA LMA +PA+RLARL + + Sbjct: 259 TAPMTETFAGLAISSVLAYAAFRTIYHNVPPGAFFAFVTALLMAYDPARRLARLQVSMER 318 Query: 318 QLVGARMLLEVVDSPASEQTEDDRPALKLSDA-----------------------RIXPG 354 V ARM+ E++D+ ++ D L+L +A R G Sbjct: 319 AAVNARMIYEILDTVPHQRDRPDATELRLGEATVELRDVRFAYGTGEEILKGVSFRAEGG 378 Query: 355 KVTALVGPSGGGKSTVLALLLRFYETREGDILIDGQPISSVSRKSLRQQTAYVGQDVYLF 414 K TALVGPSG GKST+++L+ RFY+ G+ILIDGQ I+ V+++SLR AYV Q YLF Sbjct: 379 KTTALVGPSGAGKSTIISLIPRFYDPLSGEILIDGQNIAGVTKQSLRAGLAYVSQQPYLF 438 Query: 415 ----RDTXTPPRPPA 425 RD RP A Sbjct: 439 EGSIRDNIRYGRPDA 453 >mll5362 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Mlo Mesorhizobium loti Length = 617 Score = 293 bits (751), Expect = 5e-79, Method: Compositional matrix adjust. Identities = 153/423 (36%), Positives = 246/423 (58%), Gaps = 23/423 (5%) Query: 18 LIRRLVMEQGITYWRRYLTAFALMAVAAGSTAGATYVLGQVINQAYVDKNIPGIAMFAGI 77 L+ RLV E + Y A M V AG TA + ++L ++ N+ +DK + + M A Sbjct: 46 LVARLVRESFREHMFGYGAAILSMLVVAGMTAASAWILREITNEFVIDKRVDRVNMIAAA 105 Query: 78 TVVLLFIKGVATYGHMVILNKISNAILASNQRQLFAKLMSESIGFFSQRHSSEFLARLTA 137 + +KG+A + ++++ NAI+A QR+++ +++++ I F+ SS+ + R+T Sbjct: 106 VAGIFVLKGLANFVQAYFMSRVGNAIIADRQRKIYDRILAQGIEFYHSTSSSDLITRMTN 165 Query: 138 GAKSITDVLNMLVNAIGRDFLMLISMVAVMVWQDPLMSFIGLVAVPPAMLMLRRLVKRIK 197 A++ +VL+++V + RD + L++++ VMVWQ P++S I VA P A+ + R++KR++ Sbjct: 166 NAQAARNVLDLIVTSYVRDLVTLLALIGVMVWQQPVLSLICFVAGPVAIYGVNRILKRVR 225 Query: 198 GLAYNQFTGTADIMETMQESLQGIRTVKAFTLEGTMQQRIDEHIATVESNANKMARVANR 257 A +F I++ MQE+ G+R VK+F LE M++R+ + +A VE AN +A + Sbjct: 226 NFAAMEFRSVGQIVQVMQETAIGVRVVKSFNLESLMRKRMYKAVADVEDRANNIAALEAV 285 Query: 258 SNPLMEMLGGFAVAGCLMYGGYSVVALGSTPGQFFTFLTAFLMATEPAKRLARLNIDLNS 317 ++P+ME L G A+AG +M G V+ G PG F+ A L+A EPAKRLAR+ I L S Sbjct: 286 TSPVMETLAGLAIAGAVMVSGLLVLQGGQMPGNIMAFIAALLLAYEPAKRLARVRISLES 345 Query: 318 QLVGARMLLEVVDSPASEQTEDDR-----------------------PALKLSDARIXPG 354 +VG RM+ ++ D P + + D P L D + G Sbjct: 346 GIVGVRMMFQLADEPLTLAEKPDAKPLRAGPGEIRFDAISFAYQNGPPVLDRFDLTLEAG 405 Query: 355 KVTALVGPSGGGKSTVLALLLRFYETREGDILIDGQPISSVSRKSLRQQTAYVGQDVYLF 414 K+TALVGPSGGGKST+L L++R Y+ + G +L+DGQ IS + SLR++ AYV QD +LF Sbjct: 406 KMTALVGPSGGGKSTILNLIMRMYDPKSGKVLLDGQDISHATLASLREKIAYVSQDTFLF 465 Query: 415 RDT 417 T Sbjct: 466 AGT 468 >SMb20813 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Sme Sinorhizobium meliloti Length = 607 Score = 291 bits (746), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 161/436 (36%), Positives = 246/436 (56%), Gaps = 29/436 (6%) Query: 18 LIRRLVMEQGITYWRRYLTAFALMAVAAGSTAGATYVLGQVINQAYVDKNIPGIAMFAGI 77 ++RR++ E G + Y A A + V A +TA ++ VIN+A+ K + + Sbjct: 25 ILRRVIAENGRDHIGGYAFAIACLMVVAATTAFTAWISETVINEAFAHKR-GDVVLLVCF 83 Query: 78 TVVLLFI-KGVATYGHMVILNKISNAILASNQRQLFAKLMSESIGFFSQRHSSEFLARLT 136 ++ F+ +G+ATYG V L+KI N+I+AS +R+L+ LM+ SIGFF ++ S+ A++ Sbjct: 84 SIFAAFVLRGLATYGQAVALSKIGNSIVASYKRRLYTHLMALSIGFFQEKRSAHLTAKIN 143 Query: 137 AGAKSITDVLNMLVNAIGRDFLMLISMVAVMVWQDPLMSFIGLVAVPPAMLMLRRLVKRI 196 I DVLNM V ++ RD L L+ +V VM+ +D L+S I V PP +L LR + +R+ Sbjct: 144 QNISGIRDVLNMTVTSVARDVLTLVGLVGVMISKDWLLSLITFVGAPPLLLGLRYISRRL 203 Query: 197 KGLAYNQFTGTADIMETMQESLQGIRTVKAFTLEGTMQQRIDEHIATVESNANKMARVAN 256 + + ++ MQE++QGI VKAFT+E + ++++ I E+ AN++AR++ Sbjct: 204 RLATREAVEANSRVLGAMQETIQGISIVKAFTMEDELGRKVEGIIKGAENRANRIARLSE 263 Query: 257 RSNPLMEMLGGFAVAGCLMYGGYSVVALGSTPGQFFTFLTAFLMATEPAKRLARLNIDLN 316 R+ PL E G A++G L Y + + PG F F+TA L+A +P +RLARL + L Sbjct: 264 RTAPLTETFAGLAISGVLAYAAFRTIYSNVAPGALFAFVTALLLAYDPVRRLARLQVSLE 323 Query: 317 SQLVGARMLLEVVDS-------PASEQTEDDRPALKLSDARIX----------------P 353 V ARML E++D+ P + Q ++ D R Sbjct: 324 RAAVNARMLYEILDTVPHQRDLPGARQLAFSEATVEFRDVRFSYGNGEEVLKGVSFLAEG 383 Query: 354 GKVTALVGPSGGGKSTVLALLLRFYETREGDILIDGQPISSVSRKSLRQQTAYVGQDVYL 413 GK TALVGPSG GKST+++L+ RFY+ + G ILIDGQ I++V+++SLR AYV Q YL Sbjct: 384 GKTTALVGPSGAGKSTIISLIPRFYDPQSGVILIDGQDIAAVTKQSLRNGLAYVSQQAYL 443 Query: 414 F----RDTXTPPRPPA 425 F RD RP A Sbjct: 444 FEGSIRDNIRYGRPEA 459 >BMEII0250 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Bme Brucella melitensis Length = 611 Score = 265 bits (677), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 149/438 (34%), Positives = 238/438 (54%), Gaps = 24/438 (5%) Query: 4 FPKKITD-DPYGAAILIRRLVMEQGITYWRRYLTAFALMAVAAGSTAGATYVLGQVINQA 62 F KK DP A +IRR++ E Y + YL A + GS Y++ +I++ Sbjct: 6 FKKKNRKIDPGEATRVIRRMMSENIREYKQNYLIAIIASLIVGGSNGALAYMMKPMIDKI 65 Query: 63 YVDKNIPGIAMFAGITVVLLFIKGVATYGHMVILNKISNAILASNQRQLFAKLMSESIGF 122 + ++N+ + + G + + ++G++ Y V L KI N ++A Q+++F LM + F Sbjct: 66 FYEQNLALVWVICGALLTIFVLRGISGYVQAVELAKIGNNLVARYQKRIFDHLMKLGLDF 125 Query: 123 FSQRHSSEFLARLTAGAKSITDVLNMLVNAIGRDFLMLISMVAVMVWQDPLMSFIGLVAV 182 ++ S A++ I D+LNM +++I RDF+ L+ +V +M + DP++S + Sbjct: 126 YNDTRSGHLAAQINQNVAGIRDLLNMTISSIARDFISLVGLVGMMFYMDPVLSVAIFLIG 185 Query: 183 PPAMLMLRRLVKRIKGLAYNQFTGTADIMETMQESLQGIRTVKAFTLEGTMQQRIDEHIA 242 PP +L + + +RI+ + + ++ MQES+QGI VKAFT+E ++ +ID+ I Sbjct: 186 PPLILAVAYISRRIRSVTREVVHLNSHLLGAMQESIQGIAIVKAFTMEDQLRAKIDDLID 245 Query: 243 TVESNANKMARVANRSNPLMEMLGGFAVAGCLMYGGYSVVALGSTPGQFFTFLTAFLMAT 302 E +NK+A+V+ R+ P+ E+L G AV+G L+Y GY + PG F F+TA L+A Sbjct: 246 QSEGRSNKIAKVSERTTPISEILAGVAVSGVLVYSGYRAILEHQPPGATFAFITAMLLAY 305 Query: 303 EPAKRLARLNIDLNSQLVGARMLLEVVDSPASEQTEDDRPALKLSDARI----------- 351 +PA+RLARL + L LV ARM+ EV+D ++ LK I Sbjct: 306 DPARRLARLQVGLEKALVNARMIYEVLDIEPRQRDLQGATELKAGPGEIRFDNIYFSYNQ 365 Query: 352 ------------XPGKVTALVGPSGGGKSTVLALLLRFYETREGDILIDGQPISSVSRKS 399 G+ TA+VG SG GKST+++L+ RFY+ G IL DGQ I+ V+++S Sbjct: 366 TAPVLHGVTFMAKAGETTAVVGASGAGKSTLISLVQRFYDLDRGRILFDGQDIAGVTKQS 425 Query: 400 LRQQTAYVGQDVYLFRDT 417 LR AYV Q YLF T Sbjct: 426 LRHAIAYVSQQPYLFEGT 443 >AGl552 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 587 Score = 260 bits (664), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 136/423 (32%), Positives = 238/423 (56%), Gaps = 23/423 (5%) Query: 18 LIRRLVMEQGITYWRRYLTAFALMAVAAGSTAGATYVLGQVINQAYVDKNIPGIAMFAGI 77 L+ RL E + Y A M + AG+T+ + +++ ++N Y+ + + A Sbjct: 13 LLTRLFKENFKKHVGWYSAAIVAMLLVAGTTSLSAWIMRDIVNSVYLKQGFDVVLEIAFA 72 Query: 78 TVVLLFIKGVATYGHMVILNKISNAILASNQRQLFAKLMSESIGFFSQRHSSEFLARLTA 137 + +KG+AT+ L+K N+I+A QR+++ +L+ + + FF SSE L R+T Sbjct: 73 VAAIFIVKGLATFVQSYYLSKAGNSIVAEQQRKIYDRLLKQGVSFFQNLPSSELLVRVTY 132 Query: 138 GAKSITDVLNMLVNAIGRDFLMLISMVAVMVWQDPLMSFIGLVAVPPAMLMLRRLVKRIK 197 A++ V++ +V + RD L+ ++ VM Q+ L+S I ++ P A+ +R +++R++ Sbjct: 133 NAQAARSVIDTIVTSFVRDLFSLLGLIIVMFAQNFLLSAISMIIGPVAIFSVRLVLRRVR 192 Query: 198 GLAYNQFTGTADIMETMQESLQGIRTVKAFTLEGTMQQRIDEHIATVESNANKMARVANR 257 + + +I+ +QE+ G+R +KAF+LE M+QR+++ ++ VE AN +A++ Sbjct: 193 KIMEAELASLGEIVNVVQETSIGVRVIKAFSLEKLMRQRMNKAVSDVEHRANGIAKLEAA 252 Query: 258 SNPLMEMLGGFAVAGCLMYGGYSVVALGSTPGQFFTFLTAFLMATEPAKRLARLNIDLNS 317 ++P+ME L G A+A + GY+V+ G +PG F+TA L+A EPAKRLAR+ + + Sbjct: 253 TSPIMETLSGLAIAVVIAVSGYTVLEKGGSPGDLMAFITALLLAYEPAKRLARMRVQIEG 312 Query: 318 QLVGARMLLEVVDSPASEQTEDD-----------------------RPALKLSDARIXPG 354 ++G RM+ EV+D+P + + D +P LK G Sbjct: 313 GMIGVRMMFEVLDAPLTLAEKKDAQPLPKASGNVELKNVSFEYVANQPVLKDVSVLFEGG 372 Query: 355 KVTALVGPSGGGKSTVLALLLRFYETREGDILIDGQPISSVSRKSLRQQTAYVGQDVYLF 414 K+TALVGPSG GKST++ L++R Y+ + G + I+G + VS SLR+ +YVGQ+ +LF Sbjct: 373 KMTALVGPSGSGKSTIINLMMRLYDPQSGSVEINGMDLRDVSFASLREHVSYVGQETFLF 432 Query: 415 RDT 417 T Sbjct: 433 SGT 435