BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0043.p (302 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gcvA [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 168 1e-41 ZgcvA [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 168 1e-41 ECs3668 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 168 1e-41 STM2982 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 166 5e-41 YPO1029 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 165 9e-41 >gcvA [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 305 Score = 168 bits (426), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 108/288 (37%), Positives = 155/288 (53%), Gaps = 6/288 (2%) Query: 9 IPPLPALLAFERAATQLSFRRAARDLSLSPSAISHQIRGLEEQFGTKLFVRGARQVRLTA 68 +PPL AL F+ AA LSF RAA +L ++ +A+SHQI+ LE+ G KLF R R + LT Sbjct: 5 LPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTE 64 Query: 69 DGERYLAKVSAALATLQEASRDMLRQRGEASGELWISSLPFFTSAVLLPALPEFKRRHPQ 128 +G+ Y + + L EA+R + Q A G L +S LP F L+P L F +P Sbjct: 65 EGQSYFLDIKEIFSQLTEATRKL--QARSAKGALTVSLLPSFAIHWLVPRLSSFNSAYPG 122 Query: 129 LTLRIEATHQYADFNGSRVDVAIRYGREHAAGLKVEPLVQVKGMPVCTPALVKAG--LRT 186 + +RI+A + D VDVAI YGR + GL+VE L +PVC+P L+ L+T Sbjct: 123 IDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKPLKT 182 Query: 187 PADLSREVLIHVTTQPRAWPAWLKEAGLPNLAPRGHLWLDSVPAMLEAAEHGLGVAIAIA 246 P DL++ L+H ++ R W + ++ GL ++ + +L+AA HG GVA+A Sbjct: 183 PEDLAKHTLLHDASR-RDWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVALANN 241 Query: 247 PLIKVRPGFGKRLVAPFAFEAAYSETIYLVSRTEQARDRRIAAVRRWI 294 + + G RLV PF YLV QA +IAA R+WI Sbjct: 242 VMAQSEIEAG-RLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288 >ZgcvA [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 305 Score = 168 bits (426), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 108/288 (37%), Positives = 155/288 (53%), Gaps = 6/288 (2%) Query: 9 IPPLPALLAFERAATQLSFRRAARDLSLSPSAISHQIRGLEEQFGTKLFVRGARQVRLTA 68 +PPL AL F+ AA LSF RAA +L ++ +A+SHQI+ LE+ G KLF R R + LT Sbjct: 5 LPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTE 64 Query: 69 DGERYLAKVSAALATLQEASRDMLRQRGEASGELWISSLPFFTSAVLLPALPEFKRRHPQ 128 +G+ Y + + L EA+R + Q A G L +S LP F L+P L F +P Sbjct: 65 EGQSYFLDIKEIFSQLTEATRKL--QARSAKGALTVSLLPSFAIHWLVPRLSSFNSAYPG 122 Query: 129 LTLRIEATHQYADFNGSRVDVAIRYGREHAAGLKVEPLVQVKGMPVCTPALVKAG--LRT 186 + +RI+A + D VDVAI YGR + GL+VE L +PVC+P L+ L+T Sbjct: 123 IDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKPLKT 182 Query: 187 PADLSREVLIHVTTQPRAWPAWLKEAGLPNLAPRGHLWLDSVPAMLEAAEHGLGVAIAIA 246 P DL++ L+H ++ R W + ++ GL ++ + +L+AA HG GVA+A Sbjct: 183 PEDLAKHTLLHDASR-RDWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVALANN 241 Query: 247 PLIKVRPGFGKRLVAPFAFEAAYSETIYLVSRTEQARDRRIAAVRRWI 294 + + G RLV PF YLV QA +IAA R+WI Sbjct: 242 VMAQSEIEAG-RLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288 >ECs3668 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 305 Score = 168 bits (426), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 108/288 (37%), Positives = 155/288 (53%), Gaps = 6/288 (2%) Query: 9 IPPLPALLAFERAATQLSFRRAARDLSLSPSAISHQIRGLEEQFGTKLFVRGARQVRLTA 68 +PPL AL F+ AA LSF RAA +L ++ +A+SHQI+ LE+ G KLF R R + LT Sbjct: 5 LPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTE 64 Query: 69 DGERYLAKVSAALATLQEASRDMLRQRGEASGELWISSLPFFTSAVLLPALPEFKRRHPQ 128 +G+ Y + + L EA+R + Q A G L +S LP F L+P L F +P Sbjct: 65 EGQSYFLDIKEIFSQLTEATRKL--QARSAKGALTVSLLPSFAIHWLVPRLSSFNSAYPG 122 Query: 129 LTLRIEATHQYADFNGSRVDVAIRYGREHAAGLKVEPLVQVKGMPVCTPALVKAG--LRT 186 + +RI+A + D VDVAI YGR + GL+VE L +PVC+P L+ L+T Sbjct: 123 IDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKPLKT 182 Query: 187 PADLSREVLIHVTTQPRAWPAWLKEAGLPNLAPRGHLWLDSVPAMLEAAEHGLGVAIAIA 246 P DL++ L+H ++ R W + ++ GL ++ + +L+AA HG GVA+A Sbjct: 183 PEDLAKHTLLHDASR-RDWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVALANN 241 Query: 247 PLIKVRPGFGKRLVAPFAFEAAYSETIYLVSRTEQARDRRIAAVRRWI 294 + + G RLV PF YLV QA +IAA R+WI Sbjct: 242 VMAQSEIEAG-RLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288 >STM2982 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 305 Score = 166 bits (421), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 107/288 (37%), Positives = 155/288 (53%), Gaps = 6/288 (2%) Query: 9 IPPLPALLAFERAATQLSFRRAARDLSLSPSAISHQIRGLEEQFGTKLFVRGARQVRLTA 68 +PPL AL F+ AA LSF RAA +L ++ +A+SHQI+ LE+ G KLF R R + LT Sbjct: 5 LPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTE 64 Query: 69 DGERYLAKVSAALATLQEASRDMLRQRGEASGELWISSLPFFTSAVLLPALPEFKRRHPQ 128 +G+ Y + + L EA+R + Q A G L +S P F L+P L F +P Sbjct: 65 EGQSYFLDIKEIFSQLTEATRKL--QARSAKGALTVSLPPSFAIQWLVPRLSSFNSAYPG 122 Query: 129 LTLRIEATHQYADFNGSRVDVAIRYGREHAAGLKVEPLVQVKGMPVCTPALVKAG--LRT 186 + +RI+A + D VDVAI YGR + GL+VE L +PVC+P L+ L+T Sbjct: 123 IDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKPLKT 182 Query: 187 PADLSREVLIHVTTQPRAWPAWLKEAGLPNLAPRGHLWLDSVPAMLEAAEHGLGVAIAIA 246 P DL++ L+H ++ R W A+ ++ GL ++ + +L+AA HG G+A+A Sbjct: 183 PEDLAKHTLLHDASR-RDWQAYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGIALANN 241 Query: 247 PLIKVRPGFGKRLVAPFAFEAAYSETIYLVSRTEQARDRRIAAVRRWI 294 + + G RLV PF YLV QA +IAA R+WI Sbjct: 242 VMAQSEIEAG-RLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288 >YPO1029 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 305 Score = 165 bits (418), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 104/288 (36%), Positives = 157/288 (54%), Gaps = 6/288 (2%) Query: 9 IPPLPALLAFERAATQLSFRRAARDLSLSPSAISHQIRGLEEQFGTKLFVRGARQVRLTA 68 +PPL AL AF+ AA LSF +AA +L ++ +A+SHQI+ LE+ G KLF R R + LT Sbjct: 5 LPPLNALRAFDAAARHLSFTKAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTE 64 Query: 69 DGERYLAKVSAALATLQEASRDMLRQRGEASGELWISSLPFFTSAVLLPALPEFKRRHPQ 128 +G+ Y + ++ EA+R + Q A G L +S P F L+P L F +P Sbjct: 65 EGQSYYLDIKEIFTSINEATRKL--QARSAKGALTVSLPPSFAIQWLVPRLSGFNAAYPG 122 Query: 129 LTLRIEATHQYADFNGSRVDVAIRYGREHAAGLKVEPLVQVKGMPVCTPALV--KAGLRT 186 + +RI+A + D VDVAI YGR + +GL+ E L +PVC P+L+ + GL+ Sbjct: 123 IDVRIQAVDREEDKLADDVDVAIFYGRGNWSGLRTERLYAEFLLPVCAPSLLTGENGLKV 182 Query: 187 PADLSREVLIHVTTQPRAWPAWLKEAGLPNLAPRGHLWLDSVPAMLEAAEHGLGVAIAIA 246 P+DL+ L+H T++ R W A+ ++ G+P + + +++AA HG G+A+ Sbjct: 183 PSDLANHTLLHDTSR-RDWLAYTRQLGVPQINVQQGPIFSHSAMVVQAAVHGQGIALVNN 241 Query: 247 PLIKVRPGFGKRLVAPFAFEAAYSETIYLVSRTEQARDRRIAAVRRWI 294 + + G RLV PF YLV QA +IAA R+WI Sbjct: 242 VMAQSEIEAG-RLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288