BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0030.p (299 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gcvA [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 261 1e-69 ZgcvA [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 261 1e-69 ECs3668 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 261 1e-69 STM2982 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 259 5e-69 YPO1029 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 251 1e-66 >gcvA [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 305 Score = 261 bits (668), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 145/297 (48%), Positives = 179/297 (60%), Gaps = 3/297 (1%) Query: 1 MTSRLPSLNGLRAFEAAARHMSFTLAASELNVTQTAISHQIRRLEEELGVRLFIRQNRSL 60 M+ RLP LN LR F+AAARH+SFT AA EL VTQ A+SHQI+ LE+ LG++LF R+NRSL Sbjct: 1 MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSL 60 Query: 61 SLTPEATEYLPGVRAAFNDLRLAADRLLRRDDDHVLTVSTLASLAAKWLLPRLSAFQEAH 120 LT E Y ++ F+ L A +L R LTVS L S A WL+PRLS+F A+ Sbjct: 61 LLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAY 120 Query: 121 SGIDVRITTSTSLVDFQRDKVDAAIRYGRGQWAGLRADWLMADELFPVCSPSLLQGTKPL 180 GIDVRI D D VD AI YGRG W GLR + L A+ L PVCSP LL G KPL Sbjct: 121 PGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKPL 180 Query: 181 KCPEDLRDHTLLHTSNANSDDWRLWLTAAGLPTDISKQPGVTFDLLFVTIQAAIDGIGIA 240 K PEDL HTLLH +A+ DW+ + GL I+ Q G F + +QAAI G G+A Sbjct: 181 KTPEDLAKHTLLH--DASRRDWQTYTRQLGL-NHINVQQGPIFSHSAMVLQAAIHGQGVA 237 Query: 241 MGRTSYVQDDIAKGRLVVPFKIALPADAGFYLVSPQGRADTPKLSAFRSWLGTTAHA 297 + Q +I GRLV PF L + FYLV +A+ K++AFR W+ A A Sbjct: 238 LANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWILAKAAA 294 >ZgcvA [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 305 Score = 261 bits (668), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 145/297 (48%), Positives = 179/297 (60%), Gaps = 3/297 (1%) Query: 1 MTSRLPSLNGLRAFEAAARHMSFTLAASELNVTQTAISHQIRRLEEELGVRLFIRQNRSL 60 M+ RLP LN LR F+AAARH+SFT AA EL VTQ A+SHQI+ LE+ LG++LF R+NRSL Sbjct: 1 MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSL 60 Query: 61 SLTPEATEYLPGVRAAFNDLRLAADRLLRRDDDHVLTVSTLASLAAKWLLPRLSAFQEAH 120 LT E Y ++ F+ L A +L R LTVS L S A WL+PRLS+F A+ Sbjct: 61 LLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAY 120 Query: 121 SGIDVRITTSTSLVDFQRDKVDAAIRYGRGQWAGLRADWLMADELFPVCSPSLLQGTKPL 180 GIDVRI D D VD AI YGRG W GLR + L A+ L PVCSP LL G KPL Sbjct: 121 PGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKPL 180 Query: 181 KCPEDLRDHTLLHTSNANSDDWRLWLTAAGLPTDISKQPGVTFDLLFVTIQAAIDGIGIA 240 K PEDL HTLLH +A+ DW+ + GL I+ Q G F + +QAAI G G+A Sbjct: 181 KTPEDLAKHTLLH--DASRRDWQTYTRQLGL-NHINVQQGPIFSHSAMVLQAAIHGQGVA 237 Query: 241 MGRTSYVQDDIAKGRLVVPFKIALPADAGFYLVSPQGRADTPKLSAFRSWLGTTAHA 297 + Q +I GRLV PF L + FYLV +A+ K++AFR W+ A A Sbjct: 238 LANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWILAKAAA 294 >ECs3668 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 305 Score = 261 bits (668), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 145/297 (48%), Positives = 179/297 (60%), Gaps = 3/297 (1%) Query: 1 MTSRLPSLNGLRAFEAAARHMSFTLAASELNVTQTAISHQIRRLEEELGVRLFIRQNRSL 60 M+ RLP LN LR F+AAARH+SFT AA EL VTQ A+SHQI+ LE+ LG++LF R+NRSL Sbjct: 1 MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSL 60 Query: 61 SLTPEATEYLPGVRAAFNDLRLAADRLLRRDDDHVLTVSTLASLAAKWLLPRLSAFQEAH 120 LT E Y ++ F+ L A +L R LTVS L S A WL+PRLS+F A+ Sbjct: 61 LLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAY 120 Query: 121 SGIDVRITTSTSLVDFQRDKVDAAIRYGRGQWAGLRADWLMADELFPVCSPSLLQGTKPL 180 GIDVRI D D VD AI YGRG W GLR + L A+ L PVCSP LL G KPL Sbjct: 121 PGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKPL 180 Query: 181 KCPEDLRDHTLLHTSNANSDDWRLWLTAAGLPTDISKQPGVTFDLLFVTIQAAIDGIGIA 240 K PEDL HTLLH +A+ DW+ + GL I+ Q G F + +QAAI G G+A Sbjct: 181 KTPEDLAKHTLLH--DASRRDWQTYTRQLGL-NHINVQQGPIFSHSAMVLQAAIHGQGVA 237 Query: 241 MGRTSYVQDDIAKGRLVVPFKIALPADAGFYLVSPQGRADTPKLSAFRSWLGTTAHA 297 + Q +I GRLV PF L + FYLV +A+ K++AFR W+ A A Sbjct: 238 LANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWILAKAAA 294 >STM2982 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 305 Score = 259 bits (662), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 143/291 (49%), Positives = 177/291 (60%), Gaps = 3/291 (1%) Query: 1 MTSRLPSLNGLRAFEAAARHMSFTLAASELNVTQTAISHQIRRLEEELGVRLFIRQNRSL 60 M+ RLP LN LR F+AAARH+SFT AA EL VTQ A+SHQI+ LE+ LG++LF R+NRSL Sbjct: 1 MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSL 60 Query: 61 SLTPEATEYLPGVRAAFNDLRLAADRLLRRDDDHVLTVSTLASLAAKWLLPRLSAFQEAH 120 LT E Y ++ F+ L A +L R LTVS S A +WL+PRLS+F A+ Sbjct: 61 LLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLPPSFAIQWLVPRLSSFNSAY 120 Query: 121 SGIDVRITTSTSLVDFQRDKVDAAIRYGRGQWAGLRADWLMADELFPVCSPSLLQGTKPL 180 GIDVRI D D VD AI YGRG W GLR + L A+ L PVCSP LL G KPL Sbjct: 121 PGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKPL 180 Query: 181 KCPEDLRDHTLLHTSNANSDDWRLWLTAAGLPTDISKQPGVTFDLLFVTIQAAIDGIGIA 240 K PEDL HTLLH +A+ DW+ + GL I+ Q G F + +QAAI G GIA Sbjct: 181 KTPEDLAKHTLLH--DASRRDWQAYTRQLGL-NHINVQQGPIFSHSAMVLQAAIHGQGIA 237 Query: 241 MGRTSYVQDDIAKGRLVVPFKIALPADAGFYLVSPQGRADTPKLSAFRSWL 291 + Q +I GRLV PF L + FYLV +A+ K++AFR W+ Sbjct: 238 LANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288 >YPO1029 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 305 Score = 251 bits (641), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 138/291 (47%), Positives = 175/291 (60%), Gaps = 3/291 (1%) Query: 1 MTSRLPSLNGLRAFEAAARHMSFTLAASELNVTQTAISHQIRRLEEELGVRLFIRQNRSL 60 M+ RLP LN LRAF+AAARH+SFT AA EL VTQ A+SHQI+ LE+ LG++LF R+NRSL Sbjct: 1 MSKRLPPLNALRAFDAAARHLSFTKAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSL 60 Query: 61 SLTPEATEYLPGVRAAFNDLRLAADRLLRRDDDHVLTVSTLASLAAKWLLPRLSAFQEAH 120 LT E Y ++ F + A +L R LTVS S A +WL+PRLS F A+ Sbjct: 61 LLTEEGQSYYLDIKEIFTSINEATRKLQARSAKGALTVSLPPSFAIQWLVPRLSGFNAAY 120 Query: 121 SGIDVRITTSTSLVDFQRDKVDAAIRYGRGQWAGLRADWLMADELFPVCSPSLLQGTKPL 180 GIDVRI D D VD AI YGRG W+GLR + L A+ L PVC+PSLL G L Sbjct: 121 PGIDVRIQAVDREEDKLADDVDVAIFYGRGNWSGLRTERLYAEFLLPVCAPSLLTGENGL 180 Query: 181 KCPEDLRDHTLLHTSNANSDDWRLWLTAAGLPTDISKQPGVTFDLLFVTIQAAIDGIGIA 240 K P DL +HTLLH + + DW + G+P I+ Q G F + +QAA+ G GIA Sbjct: 181 KVPSDLANHTLLH--DTSRRDWLAYTRQLGVP-QINVQQGPIFSHSAMVVQAAVHGQGIA 237 Query: 241 MGRTSYVQDDIAKGRLVVPFKIALPADAGFYLVSPQGRADTPKLSAFRSWL 291 + Q +I GRLV PF L + FYLV +A+ K++AFR W+ Sbjct: 238 LVNNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288