BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0027.p (283 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC2575 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ccr C... 149 7e-36 SSO2624 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso ... 147 2e-35 APE1484_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ap... 142 1e-33 Rv1070c [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mtu ... 141 2e-33 MT1100 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC M... 141 2e-33 >CC2575 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ccr Caulobacter vibrioides Length = 265 Score = 149 bits (376), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 97/268 (36%), Positives = 143/268 (53%), Gaps = 21/268 (7%) Query: 26 RDRVAVITLNRPDARNSLS-----DTLTPALRTMIRTCGENPEVGVLLVTGAGKAFCAGG 80 R +A++TLNRPDA N+L D + A + ++ ++ +++TGAGKAF AGG Sbjct: 9 RGHIAILTLNRPDAMNALGAPGDGDQVAAACEAI----NDDQDIRCVILTGAGKAFSAGG 64 Query: 81 NVKGMGAHR-----DKKKLEMSYEDKVADLQERQRLLTGALASVRKPTIAALPGPAVGAG 135 +VK M A + K+ Y + R++ A+ + P+IAA+ G A+G G Sbjct: 65 DVKAMKAREGAFGGNGVKVRDGYRKNI------HRIVR-AIYGLEVPSIAAVNGAAIGLG 117 Query: 136 LAIAMACDIRIAAQSAFISTGYLRVALSGDYGMAWLLTRLVGTSRARELMFTSEKVDAAR 195 +A DIRIAA +A +L++ L G AWL+ R +G SRA EL+FT + +DAA+ Sbjct: 118 CDVACMTDIRIAADTARFGVTFLKLGLIPGDGGAWLMPRTIGMSRAAELLFTGDVIDAAK 177 Query: 196 CEQIGLVNRVVPDETLQDEAFALAKSIAEGPTLALRYMKDNLDEALQFDFATARDHEAER 255 + GL+++ VP L EA ALA+ IA+ P ALR K L + T + A Sbjct: 178 AAEWGLISKAVPAGDLMGEALALAERIAQQPPHALRMAKSLLKHGQTASYDTLMEMSAAA 237 Query: 256 LIRLTTTADHKEAVQAFIEKRKPVCRGS 283 T DH E V A +EKR PV +G+ Sbjct: 238 QAIAHHTEDHMEGVDAILEKRSPVFKGA 265 >SSO2624 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso Sulfolobus solfataricus Length = 266 Score = 147 bits (372), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 89/252 (35%), Positives = 137/252 (54%), Gaps = 11/252 (4%) Query: 27 DRVAVITLNRPDARNSLSDTLTPALRTMIRTCGENPEVGVLLVTGAGKAFCAGGNVKGMG 86 D + +I LNRPD N+++ + L ++ + ++ V+++TG GKAF AG +VK M Sbjct: 18 DNIGIIKLNRPDKLNAINFQMVDELVDVLNKLDNDDKIKVVIITGNGKAFSAGADVKEM- 76 Query: 87 AHRDKKKLEMSYEDKVADLQERQRLLTGALASVRKPTIAALPGPAVGAGLAIAMACDIRI 146 LE E+ +++ L L + +KP IAAL G G GL +AMACDI I Sbjct: 77 -------LETPLEEI---MKKGHMPLWEKLRTFKKPVIAALNGITAGGGLELAMACDIII 126 Query: 147 AAQSAFISTGYLRVALSGDYGMAWLLTRLVGTSRARELMFTSEKVDAARCEQIGLVNRVV 206 A++SA + + + + G LTR++G +A EL+ T + +D+ E+ GLVN+VV Sbjct: 127 ASESAKLGQPEINLGIMPGAGGTQRLTRVLGKYKAMELVLTGKLIDSKEAERYGLVNKVV 186 Query: 207 PDETLQDEAFALAKSIAEGPTLALRYMKDNLDEALQFDFATARDHEAERLIRLTTTADHK 266 PD +L DEA LA+ IAE P +++ K+ + A D E T + K Sbjct: 187 PDNSLIDEAIRLAREIAEKPIISIILAKEAVARAWDTLLQQGLDFERRNFYLALNTKEAK 246 Query: 267 EAVQAFIEKRKP 278 E ++AF+EKRKP Sbjct: 247 EGMRAFLEKRKP 258 >APE1484_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ape Aeropyrum pernix Length = 257 Score = 142 bits (357), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 94/264 (35%), Positives = 137/264 (51%), Gaps = 9/264 (3%) Query: 19 DELLCVIRDRVAVITLNRPDARNSLSDTLTPALRTMIRTCGENPEVGVLLVTGAGKAFCA 78 + LL + +A I LNRPD N++S + L + E +V +++TGAG+AF A Sbjct: 2 ETLLVRVEKPIAWIVLNRPDKLNAISPKMIMELSQALDELEERSDVRAVILTGAGRAFSA 61 Query: 79 GGNVKGMGAHRDKKKLEMSYEDKVADLQERQRLLTGALASVRKPTIAALPGPAVGAGLAI 138 G +V L S + QE LT + KP I A+ G A+G GL + Sbjct: 62 GADVTAFAQVTPIDILRFSRK-----FQE----LTLKIQFYTKPVIVAIKGYALGGGLEL 112 Query: 139 AMACDIRIAAQSAFISTGYLRVALSGDYGMAWLLTRLVGTSRARELMFTSEKVDAARCEQ 198 AM+ DIRIA++ A + + + G L RL G +RA+EL+ T + + A+ E+ Sbjct: 113 AMSGDIRIASEDAMLGQPEINLGFIPGAGGTQRLARLAGPARAKELIMTGDMIPASDAEK 172 Query: 199 IGLVNRVVPDETLQDEAFALAKSIAEGPTLALRYMKDNLDEALQFDFATARDHEAERLIR 258 +G+VNRVVP E L+ EA +LA +AE P +AL K +D L+ + EA Sbjct: 173 MGIVNRVVPPELLEQEASSLALKLAEKPPIALAAAKYAIDFGLESNIWAGLQLEASLFSV 232 Query: 259 LTTTADHKEAVQAFIEKRKPVCRG 282 L +T D E V AF+EKRKP +G Sbjct: 233 LFSTEDVIEGVTAFLEKRKPKFKG 256 >Rv1070c [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mtu Mycobacterium tuberculosis H37Rv Length = 257 Score = 141 bits (355), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 92/263 (34%), Positives = 143/263 (54%), Gaps = 14/263 (5%) Query: 18 TDELLCVIRD-RVAVITLNRPDARNSLSDTLTPALRTMIRTCGENPEVGVLLVTGAGKAF 76 T E + V RD RV +ITLNRP A N+L+ + + + ++P++G +++TG+ KAF Sbjct: 2 TYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAF 61 Query: 77 CAGGNVKGMGAHRDKKKLEMSYEDK-VADLQERQRLLTGALASVRKPTIAALPGPAVGAG 135 AG ++K M ++++ D AD G LA+VR PTIAA+ G A+G G Sbjct: 62 AAGADIKEMA--------DLTFADAFTADFFATW----GKLAAVRTPTIAAVAGYALGGG 109 Query: 136 LAIAMACDIRIAAQSAFISTGYLRVALSGDYGMAWLLTRLVGTSRARELMFTSEKVDAAR 195 +AM CD+ IAA +A +++ + G + LTR +G ++A +L+ T +DAA Sbjct: 110 CELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAE 169 Query: 196 CEQIGLVNRVVPDETLQDEAFALAKSIAEGPTLALRYMKDNLDEALQFDFATARDHEAER 255 E+ GLV+RVVP + L EA A A +I++ A R K+ ++ A + + +E Sbjct: 170 AERSGLVSRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRL 229 Query: 256 LIRLTTTADHKEAVQAFIEKRKP 278 T D E + AFIEKR P Sbjct: 230 FHSAFATEDQSEGMAAFIEKRAP 252 >MT1100 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC Mycobacterium tuberculosis CDC1551 Length = 257 Score = 141 bits (355), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 92/263 (34%), Positives = 143/263 (54%), Gaps = 14/263 (5%) Query: 18 TDELLCVIRD-RVAVITLNRPDARNSLSDTLTPALRTMIRTCGENPEVGVLLVTGAGKAF 76 T E + V RD RV +ITLNRP A N+L+ + + + ++P++G +++TG+ KAF Sbjct: 2 TYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAF 61 Query: 77 CAGGNVKGMGAHRDKKKLEMSYEDK-VADLQERQRLLTGALASVRKPTIAALPGPAVGAG 135 AG ++K M ++++ D AD G LA+VR PTIAA+ G A+G G Sbjct: 62 AAGADIKEMA--------DLTFADAFTADFFATW----GKLAAVRTPTIAAVAGYALGGG 109 Query: 136 LAIAMACDIRIAAQSAFISTGYLRVALSGDYGMAWLLTRLVGTSRARELMFTSEKVDAAR 195 +AM CD+ IAA +A +++ + G + LTR +G ++A +L+ T +DAA Sbjct: 110 CELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAE 169 Query: 196 CEQIGLVNRVVPDETLQDEAFALAKSIAEGPTLALRYMKDNLDEALQFDFATARDHEAER 255 E+ GLV+RVVP + L EA A A +I++ A R K+ ++ A + + +E Sbjct: 170 AERSGLVSRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRL 229 Query: 256 LIRLTTTADHKEAVQAFIEKRKP 278 T D E + AFIEKR P Sbjct: 230 FHSAFATEDQSEGMAAFIEKRAP 252