BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0025.p (594 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3593 [I] COG1960 Acyl-CoA dehydrogenases Pae Pseudomonas aerug... 535 e-151 Rv3797 [I] COG1960 Acyl-CoA dehydrogenases Mtu Mycobacterium tub... 241 4e-63 MT3904 [I] COG1960 Acyl-CoA dehydrogenases MtC Mycobacterium tub... 241 4e-63 PA3972 [I] COG1960 Acyl-CoA dehydrogenases Pae Pseudomonas aerug... 237 6e-62 mll0685 [I] COG1960 Acyl-CoA dehydrogenases Mlo Mesorhizobium loti 219 2e-56 >PA3593 [I] COG1960 Acyl-CoA dehydrogenases Pae Pseudomonas aeruginosa Length = 575 Score = 535 bits (1378), Expect = e-151, Method: Compositional matrix adjust. Identities = 286/572 (50%), Positives = 375/572 (65%), Gaps = 12/572 (2%) Query: 22 PDTTGMNFYRADPALTDLLKLHLPDALFRHIEPHLDRLGGLAGGYLDECARLADRHTPVL 81 PD+ G+N Y DPAL LL+++LP AL P L+RLG AGG LD A AD++ PVL Sbjct: 16 PDSRGLNLYTCDPALERLLEVYLPPALLAEWRPLLERLGARAGGELDVLALAADKNPPVL 75 Query: 82 HQRDKFGRDVQHIEYHPAYREIEKAAFGEFGIHALSLRKGIMGWPDKYPVVAKHAFTFLF 141 R + G D+Q I HP Y +E+ A+ E G+ ++S R PD P + K+A T LF Sbjct: 76 APRTRRGEDLQSIRKHPDYVALERVAYAELGLASMSHR------PDGPPPLVKYALTHLF 129 Query: 142 NQTEFGMGCPINVTDGCAKLLTNFGSEALKAKYLDGLTQTDMSRLTQGGQFMTEKEGGSD 201 Q EFG+ CP+++TD + L FG+ L +YL L D L QG FMTE+ GSD Sbjct: 130 VQAEFGLCCPVSMTDSLTRTLRRFGAPELVERYLPSLASRDFDELFQGAMFMTEQAAGSD 189 Query: 202 VGTLTTRAVQEGDHWRLYGEKWFCSNADAKVVMLLARPEGAGAGTRGVGLFLMPRFLDDG 261 V T A ++G W+LYG+KWFCSN DA + M+LARPEGA G +GV LFL+P+ +DG Sbjct: 190 VARTRTVAREQGGEWKLYGDKWFCSNPDADLAMVLARPEGAPEGMKGVTLFLLPKVREDG 249 Query: 262 SQNHYRIVRLKDKLGTRSMASGEIKLEGAIAYAVGKLDRGFVQMAEMVNSSRLSNGVKST 321 ++N YRIVRLKDKLG+RSMASGE++LEGA AY +G++ RGF QMA+MVN SRLSNGV++ Sbjct: 250 TRNAYRIVRLKDKLGSRSMASGEVRLEGASAYLIGEIGRGFQQMADMVNMSRLSNGVRAA 309 Query: 322 ALMRRAWHDAITVAKGRVVFGQRIIDLPLARRQLMKIMLPTEQALSMSFLTADALDRAEA 381 LMRRA +A+ VA+ R FG+ +ID+PL ++QL+K+MLPTEQA SM A L RA+ Sbjct: 310 GLMRRALSEALFVARHRRAFGKHLIDMPLMQKQLLKMMLPTEQARSMFMQIATLLPRADG 369 Query: 382 GSQDAAALLRILTPTLKFRATRDARKVCGDAMEMRGGIGYIEEFVTPRLLRDAHLGSIWE 441 G +A +RILTP +KFRA RDAR+V GDAME+RGG+GYIEE+ PRL+RDAHLGSIWE Sbjct: 370 GEVEAQKCVRILTPLIKFRACRDARRVTGDAMEVRGGVGYIEEWSDPRLVRDAHLGSIWE 429 Query: 442 GTGNIVAIDALKRAVGRHGADNALAADLHARLDDSPNVPQAWRNRLRDLSDRAVALAREV 501 GT NIVA+D + RAV R A L L LDDS ++P R+ +L R VA +V Sbjct: 430 GTSNIVALD-VARAVSREQALEPLQRHLRRLLDDS-DLPGDARDLFDELLVRVVATMADV 487 Query: 502 ASRVDNEGDARRATSLLYHVASAIALAWEGGRIHEMRGDARRLLLSRMVIDHRVMPSDPF 561 A R +E R+A S LYH+ +AI +AWE R D RRL L+ +V H+++P DP Sbjct: 488 AERRQDE-QVRQAGSALYHLCTAIFMAWEASR---QAPDQRRLALAFLVARHKLLPRDPL 543 Query: 562 RLAENTVQRRMTEHLLGDRAVGMAEVGELLDA 593 L T Q + ++G+ + AE +LL A Sbjct: 544 HLEGWTDQAELLARVVGEVPLSQAEAMQLLPA 575 >Rv3797 [I] COG1960 Acyl-CoA dehydrogenases Mtu Mycobacterium tuberculosis H37Rv Length = 593 Score = 241 bits (615), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 163/457 (35%), Positives = 235/457 (51%), Gaps = 26/457 (5%) Query: 26 GMNFYRADPALTDLLKLHL-PDALFRHIEPHLDRLGGLAGGYLDECARLADRHTPVLHQR 84 G+N+Y DP L ++ +L PD L EPHL R+G L GG + A DR+ P L + Sbjct: 33 GLNWYLTDPTLQFIMAYYLRPDEL-AFAEPHLTRIGELTGGPVTRWAEETDRNPPRLERY 91 Query: 85 DKFGRDVQHIEYHPAYREIEKAAF-GEFGIHALSLRKGIMGWPDKYPVVAKHAFTFLFNQ 143 D++G D+ + ++ + ++A + + R G+ P +A A +L NQ Sbjct: 92 DRWGHDISRVVLPESFIQSKRAVIEARQAVRDDAARAGVK------PSLALFAADYLLNQ 145 Query: 144 TEFGMGCPINVTDGCAK-LLTNFGSEALKAKYLDGLTQTDMSRLTQGGQFMTEKEGGSDV 202 + GM C + + L+T + ++ L L + + Q +TE+ GGSD+ Sbjct: 146 ADIGMACALATGGNMVRSLVTAYAPPDVREFVLGKLNSGEWD--GEAAQLLTERAGGSDL 203 Query: 203 GTLTTRAVQEGDHWRLYGEKWFCSNADAKVVMLLARPEGAGAGTRGVGLFLMPRFLDDGS 262 G L T A + GD W L G KWF SN + ++LA+PEGA TRGV FL+ R DGS Sbjct: 204 GALETTATRSGDVWLLNGFKWFASNCAGEAFVVLAKPEGAPDSTRGVATFLVLRTRRDGS 263 Query: 263 QNHYRIVRLKDKLGTRSMASGEIKLEGAIAYAV--------GKLD-RGFVQMAEMVNSSR 313 +N RI RLKDKLGTRS+ASGEI+ A A+ + G D +G +M E+ N R Sbjct: 264 RNGVRIRRLKDKLGTRSVASGEIEFVDAEAFLLSGEPSADAGPSDGKGLTRMMELTNRLR 323 Query: 314 LSNGVKSTALMRRAWHDAITVAKGRVVFGQRIIDLPLARRQLMKIMLPTEQALSMSFLTA 373 L + RRA +++ A R FG +ID PL RR+L ++++ E AL+M F Sbjct: 324 LGTASFALGNARRALVESLCYAGQRRAFGGALIDKPLMRRKLAEMVVDVEAALAMVF--- 380 Query: 374 DALDRAEAGSQDAAALLRILTPTLKFRATRDARKVCGDAMEMRGGIGYIEEFVTPRLLRD 433 D A Q RI P K + R V DA+E+ GG GYIE + RLLRD Sbjct: 381 DGFGAANH-RQPRCLPQRIAVPVTKLKTCRLGITVASDAIEIHGGNGYIETWPVARLLRD 439 Query: 434 AHLGSIWEGTGNIVAIDALKRAVGRHGADNALAADLH 470 A + +IWEG NI+ +D ++R + + A L A L Sbjct: 440 AQVNTIWEGPDNILCLD-VRRGIEQTRAHETLLARLR 475 >MT3904 [I] COG1960 Acyl-CoA dehydrogenases MtC Mycobacterium tuberculosis CDC1551 Length = 593 Score = 241 bits (615), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 163/457 (35%), Positives = 235/457 (51%), Gaps = 26/457 (5%) Query: 26 GMNFYRADPALTDLLKLHL-PDALFRHIEPHLDRLGGLAGGYLDECARLADRHTPVLHQR 84 G+N+Y DP L ++ +L PD L EPHL R+G L GG + A DR+ P L + Sbjct: 33 GLNWYLTDPTLQFIMAYYLRPDEL-AFAEPHLTRIGELTGGPVTRWAEETDRNPPRLERY 91 Query: 85 DKFGRDVQHIEYHPAYREIEKAAF-GEFGIHALSLRKGIMGWPDKYPVVAKHAFTFLFNQ 143 D++G D+ + ++ + ++A + + R G+ P +A A +L NQ Sbjct: 92 DRWGHDISRVVLPESFIQSKRAVIEARQAVRDDAARAGVK------PSLALFAADYLLNQ 145 Query: 144 TEFGMGCPINVTDGCAK-LLTNFGSEALKAKYLDGLTQTDMSRLTQGGQFMTEKEGGSDV 202 + GM C + + L+T + ++ L L + + Q +TE+ GGSD+ Sbjct: 146 ADIGMACALATGGNMVRSLVTAYAPPDVREFVLGKLNSGEWD--GEAAQLLTERAGGSDL 203 Query: 203 GTLTTRAVQEGDHWRLYGEKWFCSNADAKVVMLLARPEGAGAGTRGVGLFLMPRFLDDGS 262 G L T A + GD W L G KWF SN + ++LA+PEGA TRGV FL+ R DGS Sbjct: 204 GALETTATRSGDVWLLNGFKWFASNCAGEAFVVLAKPEGAPDSTRGVATFLVLRTRRDGS 263 Query: 263 QNHYRIVRLKDKLGTRSMASGEIKLEGAIAYAV--------GKLD-RGFVQMAEMVNSSR 313 +N RI RLKDKLGTRS+ASGEI+ A A+ + G D +G +M E+ N R Sbjct: 264 RNGVRIRRLKDKLGTRSVASGEIEFVDAEAFLLSGEPSADAGPSDGKGLTRMMELTNRLR 323 Query: 314 LSNGVKSTALMRRAWHDAITVAKGRVVFGQRIIDLPLARRQLMKIMLPTEQALSMSFLTA 373 L + RRA +++ A R FG +ID PL RR+L ++++ E AL+M F Sbjct: 324 LGTASFALGNARRALVESLCYAGQRRAFGGALIDKPLMRRKLAEMVVDVEAALAMVF--- 380 Query: 374 DALDRAEAGSQDAAALLRILTPTLKFRATRDARKVCGDAMEMRGGIGYIEEFVTPRLLRD 433 D A Q RI P K + R V DA+E+ GG GYIE + RLLRD Sbjct: 381 DGFGAANH-RQPRCLPQRIAVPVTKLKTCRLGITVASDAIEIHGGNGYIETWPVARLLRD 439 Query: 434 AHLGSIWEGTGNIVAIDALKRAVGRHGADNALAADLH 470 A + +IWEG NI+ +D ++R + + A L A L Sbjct: 440 AQVNTIWEGPDNILCLD-VRRGIEQTRAHETLLARLR 475 >PA3972 [I] COG1960 Acyl-CoA dehydrogenases Pae Pseudomonas aeruginosa Length = 549 Score = 237 bits (604), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 166/478 (34%), Positives = 237/478 (49%), Gaps = 38/478 (7%) Query: 6 QDPKTSAATNQPGLLAPDTTGMNFYRADPALTDLLKLHLPDALFRHIEPHLDRLGGLAGG 65 Q +T TNQ P G N YR D L + ++ + E L R G LAGG Sbjct: 5 QYAETHEVTNQ----VPSLDGANLYRLDLPLQEWVRRYQGG----WAEERLQRYGELAGG 56 Query: 66 YLDECARLADRHTPVLHQRDKFGRDVQHIEYHPAYREIEKAAFGEFGIHALSLRKGIMGW 125 L LA++H P H D++G V +E+HPAY E+ +AA E + +L W Sbjct: 57 PLMAAGFLANQHKPEFHSHDRYGNRVDLVEFHPAYHELMRAAI-EHELPSLP-------W 108 Query: 126 PDKYP--VVAKHAFTFLFNQTEFGMGCPINVTDGC-------AKLLTNFGSEALKAKYLD 176 D P VA+ ++L +Q E G GCP+ +T A L + + L +Y Sbjct: 109 TDPRPGAQVARAGLSYLHSQAEAGTGCPLTMTYASVPAIRLQADLAEKWLPKILSREYDP 168 Query: 177 GLTQTDMSRLTQGGQFMTEKEGGSDVGTLTTRAVQ-----EGDHWRLYGEKWFCSNADAK 231 + G MTEK+GG+DV TTRA G + L G KWFCS Sbjct: 169 RNVPMEQKAGVTIGMAMTEKQGGTDVRANTTRAYPVGIPGPGQAYELVGHKWFCSAPMCD 228 Query: 232 VVMLLARPEGAGAGTRGVGLFLMPRFLDDGSQNHYRIVRLKDKLGTRSMASGEIKLEGAI 291 + LA + +G+ FL+PR DGS+N + I RLKDKLG S AS EI+ GA+ Sbjct: 229 AFLTLAYTD------KGLTCFLLPRHRPDGSRNQFYIQRLKDKLGNWSNASSEIEYRGAL 282 Query: 292 AYAVGKLDRGFVQMAEMVNSSRLSNGVKSTALMRRAWHDAITVAKGRVVFGQRIIDLPLA 351 A+ VG+ RG + EMV +R + S+ALMR+A A R V G+ + + PL Sbjct: 283 AWMVGEEGRGVPTIIEMVAMTRFDCMIGSSALMRQALTQAAHHCAYRKVGGRVLAEQPLM 342 Query: 352 RRQLMKIMLPTEQALSMSFLTADALDRAEAGSQDAAALLRILTPTLKFRATRDARKVCGD 411 + L + L +E AL+++ ALDRA ++ A R++T K+ + A + + Sbjct: 343 QNVLADLALESEAALALTLRMGHALDRAHDEQEEKFA--RLVTAVGKYWICKRAPAMINE 400 Query: 412 AMEMRGGIGYIEEFVTPRLLRDAHLGSIWEGTGNIVAIDALKRAVGRHGADNALAADL 469 A E GG GY+EE + PRL R+A + SIWEG+GN+ +D L+ G +AL A+L Sbjct: 401 ASECMGGAGYVEETILPRLYREAPVNSIWEGSGNVQCLDVLRALSKEPGVLDALFAEL 458 >mll0685 [I] COG1960 Acyl-CoA dehydrogenases Mlo Mesorhizobium loti Length = 548 Score = 219 bits (557), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 163/462 (35%), Positives = 228/462 (49%), Gaps = 37/462 (8%) Query: 10 TSAATNQPGLLAPDTTGMNFYRADPALTDLLKLHLPDALFRHIEPHLDRLGGLAGGYL-- 67 T TNQP P TG N +R DP L L + R +P L GL L Sbjct: 8 TDDVTNQP----PPLTGGNAWRGDPLLIQLAE--------RFSDPVRKDLDGLGRFVLTQ 55 Query: 68 --DECARLADRHTPVLHQRDKFGRDVQHIEYHPAYREIEKAAFGEFGIHALSLRKGIMGW 125 E ARLA+ TP L D+ GR + +E+HPAY + + + G+H+ G Sbjct: 56 EAQELARLANVETPKLRTHDRQGRRIDLVEFHPAYHALMRRSVAN-GLHSSVWENGDAEI 114 Query: 126 PDKYPVVAKHAFTFLFNQTEFGMGCPINVTDGC-------AKLLTNFGSEALKAKYLDGL 178 ++ V A A +L + E G CPI +T KL + KY Sbjct: 115 GRRHQVRA--ARFYLTAELETGHLCPITMTSASLAALMASPKLFREWAPRVTTRKYDQSQ 172 Query: 179 TQTDMSRLTQGGQFMTEKEGGSDVGTLTTRAVQEGD-HWRLYGEKWFCSNADAKVVMLLA 237 G MTEK+GG+DV TRA + G +RL G KWF S + ++LA Sbjct: 173 KPPVEKTGLTLGMGMTEKQGGTDVRANVTRAERAGSGFYRLTGHKWFMSAPMSDAFLVLA 232 Query: 238 R-PEGAGAGTRGVGLFLMPRFLDDGSQNHYRIVRLKDKLGTRSMASGEIKLEGAIAYAVG 296 + PEG + FL+PR L DGS N +R RLKDKLG RS AS E++ AI +G Sbjct: 233 QAPEG-------LSCFLVPRVLGDGSGNGFRFQRLKDKLGNRSNASSEVEFVNAIGEMIG 285 Query: 297 KLDRGFVQMAEMVNSSRLSNGVKSTALMRRAWHDAITVAKGRVVFGQRIIDLPLARRQLM 356 + G + +MV +RL V S+A+MR +A+ A+ R VFG +I+ PL +R L Sbjct: 286 EPGAGVKTIMDMVTLTRLDCAVASSAIMRAGLAEAVHHARHRQVFGSTLIEQPLMQRVLA 345 Query: 357 KIMLPTEQALSMSFLTADALDRAEAGSQDAAALLRILTPTLKFRATRDARKVCGDAMEMR 416 + L A ++SF A + D A A + AA R +TP +K+ + A + +AME Sbjct: 346 DMALDVAAATALSFRLARSFDEA-ASDRGEAAFARAMTPVVKYWVCKIAPPLLYEAMECL 404 Query: 417 GGIGYIEEFVTPRLLRDAHLGSIWEGTGNIVAIDALKRAVGR 458 GG GY+EE R R+A + +IWEG+GN++A+D L R +GR Sbjct: 405 GGNGYVEEAPLARYYREAPVNAIWEGSGNVMALDVL-RVLGR 445