BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0003.p (731 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI0197 [M] COG0739 Membrane proteins related to metalloendopep... 364 e-100 AGl1345 [M] COG0739 Membrane proteins related to metalloendopept... 348 3e-95 SMc02432 [M] COG0739 Membrane proteins related to metalloendopep... 344 4e-94 mlr3423 [M] COG0739 Membrane proteins related to metalloendopept... 303 1e-81 CC3034 [M] COG0739 Membrane proteins related to metalloendopepti... 215 4e-55 >BMEI0197 [M] COG0739 Membrane proteins related to metalloendopeptidases Bme Brucella melitensis Length = 651 Score = 364 bits (935), Expect = e-100, Method: Compositional matrix adjust. Identities = 248/657 (37%), Positives = 356/657 (54%), Gaps = 39/657 (5%) Query: 62 IDLGHEPPLSVDGTEAAVIDRRRVSVQWFSGTILTGLCGAALIGGAVFASLDGEMTFAKV 121 +D G EPPLSV G RR VS +W +GT LTG+ LIG A+FA+LDG A Sbjct: 9 LDPGDEPPLSVGGRRRPPD-RREVSARWLAGTFLTGVTSCMLIGIALFAALDGREQLATP 67 Query: 122 PERVEGALRGAFTGNDRVVSLHKGDRLPPPSESSASRSLVR--VSTVTRVGNRDVMRVRP 179 PE + T +D KG RL +R R +ST+ RVG R+V+R +P Sbjct: 68 PEILARNEMPGITEDDTAT---KGGRLISTVSQQKTRDRRRFDLSTMQRVGEREVIRTKP 124 Query: 180 F--IRISGNLSMTTSDLSAKIPAFNAQRLLTDVGSDTPAAAEDPNAA----AEPDAEVSF 233 F +R++ + T+ K P FNA + S+ PAA + +A A+ ++EVS Sbjct: 125 FEFVRMALAVDHPTN---RKYPPFNAMTIF----SEGPAAPQPSDAGQIYGAKVESEVSL 177 Query: 234 VTKDLGSVLPKAKLAAVVALDDVLMRVRDAANWRGSGGSVRYASLANAAADASGAGPDMR 293 D ++ + +D+V VRD + G V+ ASL + A G D Sbjct: 178 RMVDFPISTATFDASSDLTVDEVEKVVRDTGGLL-TDGDVQVASL-HYVDPARFGGNDSP 235 Query: 294 MAYATEGNTSDPYAGFETRVVPENVTLLPKTK-EQVTGGNPVGERVHLVKKGDSITSILR 352 A + P G ++ ENV++ P++ EQV G E + ++ I L Sbjct: 236 FALS-------PPLG--VKITQENVSIAPRSDDEQVNEG--FSEELIPFRQTADIAQALE 284 Query: 353 DQGATPDEAKAIAATLGPRGRDGGLKEGQKVRILMAPAAPGPNVRLQPYRVIVANESVIE 412 D G T ++A +A L LK+G +R+ + + R + N + Sbjct: 285 DAGYTGEDASNMAEALAKLMNSPRLKQGSVLRV----GTESHDGIDRIVRASIYNRTTHL 340 Query: 413 AVAALSDLGKYVAVDVQSMNTVTETA-DNSSDDDEDDGSGVRLYQSIYETALRNKVPPTV 471 AL+D +YV D + +TA D ++ G+ +Y I AL + T+ Sbjct: 341 VTVALNDRQQYVPSDEPEETPLLQTAFDGNAAPAAIRGNLPSVYDGISHAALAYGMTETM 400 Query: 472 IEDMVKIYSYDVDFQRKVQPGDSFDVFFAGEDEGVTSTEKTEVLYAALTVGGETKKYYRF 531 E +VK+ + DVD Q ++ P D+ D FF+ D+ +++LY A T GG T+K+YR+ Sbjct: 401 REQLVKMLASDVDLQARLSPSDAIDAFFSLPDDPEKPENDSQLLYVAATFGGTTRKFYRY 460 Query: 532 QSSDDGLVDYYDETGKSAKKFLVRKPVNNAIMRSGFGGRRHPILGYVKMHTGVDWATAYG 591 Q+ D G VDYY+E GKSAK+FL+R PV N I RS FG RRHPILGY +MHTGVDWA G Sbjct: 461 QAPD-GSVDYYNEDGKSAKQFLLRNPVPNGIFRSPFGMRRHPILGYTRMHTGVDWAAPRG 519 Query: 592 TPIFASGNGVLEKVGYEGGYGKYIRMKHANGYETAYGHMSAFAKGMEIGKKVRQGQVIGF 651 TPI A+GNGV+EK G+ GYG ++HANGY T+Y H +A A+G+ G +VRQGQVIG+ Sbjct: 520 TPIIAAGNGVVEKAGWSNGYGNQTLIRHANGYVTSYSHQNAIARGITPGARVRQGQVIGY 579 Query: 652 VGSTGQSTGPHVHYEILVNGRFVDPMRVKLPRGRSLEGPMLANFEKERDRIEAQMSS 708 VGSTG STGPH+HYE++VNG VD +R++LP ++L+G F++ERDRI+ ++S Sbjct: 580 VGSTGLSTGPHLHYELIVNGTKVDALRIRLPDNKALKGKEFEAFKQERDRIDTLLNS 636 >AGl1345 [M] COG0739 Membrane proteins related to metalloendopeptidases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 648 Score = 348 bits (893), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 233/650 (35%), Positives = 343/650 (52%), Gaps = 37/650 (5%) Query: 64 LGHEPPLSVDGTEAAVIDRRRVSVQWFSGTILTGLCGAALIGGAVFASLDGEMTFAKVPE 123 LG EPP+ +G A DRR +S++W SGT LTG+ + L+G A+FA+LDG A E Sbjct: 11 LGTEPPILAEGRRAP--DRREISLRWLSGTFLTGITSSILMGVALFAALDGRQQLAIPAE 68 Query: 124 RVEGALRGAFTGNDRVVSLHKGDRLPPPSESS--ASRSLVRVSTVTRVGNRDVMRVRPFI 181 A A GN+ + +G RL P+ ++ + RS++ VSTV G+++V+R PF Sbjct: 69 ----AFAKADMGNNATEAARRGTRLVAPNIAARPSDRSIMEVSTVINEGDKEVVRKVPFS 124 Query: 182 RISGNLSMTTSDLSAKIPAFNAQRLL-TDVGSDTPAAAEDPNAA---AEPDAEVSFVTKD 237 + L+ + PAF+ + ++ D PA A +E ++EVS T Sbjct: 125 HVKIPLASNYAKQD-DYPAFDPLNIFASNDDKDAPAPAASRTGTIYGSEVESEVSLKTVA 183 Query: 238 LGSVLPKAKLAAVVALDDVLMRVRDAANWRGSGGSVRYASLANAAADASGAGPDMRMAYA 297 K A ++ D+V VR S GS+ AA D R Sbjct: 184 FPVQHSKYAFAGSLSFDEVEEAVR-------SNGSILTDGNEQVAALYY---IDPRRFDN 233 Query: 298 TEGNTSDPYAGFETRVVPENVTLLPKTKEQVTGGNPVGERVHLV---KKGDSITSILRDQ 354 EG+ D AG RVV +N+++ V PV E V ++ ++I + L Sbjct: 234 DEGDV-DITAGLAARVVEQNMSVSTPQSSSV----PVKEYADDVIPSRQTETIEAALFGA 288 Query: 355 GATPDEAKAIAATLGPRGRDGGLKEGQKVRI-LMAPAAPGPNVRLQPYRVIVANESVIEA 413 G + ++ IA L P+ + ++ G +R+ ++ VR+ YR + Sbjct: 289 GYSKAQSSEIAKLLSPQIQSENVESGDVLRVGIIQEDEKSDIVRVSLYR-----KGRHMV 343 Query: 414 VAALSDLGKYVAVDVQSMNTVTETADNSSDDDEDDGSGVRLYQSIYETALRNKVPPTVIE 473 A+ D +V TA +S+ +Y +Y AL + +++ Sbjct: 344 TMAIDDHKNFVKASEPPKLDAVATAFDSTPAPAAGRDLPSVYDGVYRAALAYGMNQSMVS 403 Query: 474 DMVKIYSYDVDFQRKVQPGDSFDVFFAGEDEGVTSTEKTEVLYAALTVGGETKKYYRFQS 533 ++K+ + VDFQ +++P D+ + FF+ ED +T+K+E+LY G ++YRFQS Sbjct: 404 QLIKLLASSVDFQAQLKPTDTLEAFFSVEDADGKATDKSELLYVNAKFGDNETRFYRFQS 463 Query: 534 SDDGLVDYYDETGKSAKKFLVRKPVNNAIMRSGFGGRRHPILGYVKMHTGVDWATAYGTP 593 +D VDY+DE GKS ++FL+R PV N M SGFG RRHP+L + +MHTG DWA A GTP Sbjct: 464 PEDNSVDYFDENGKSIRQFLLRNPVPNGRMTSGFGMRRHPVLKFSRMHTGTDWAAARGTP 523 Query: 594 IFASGNGVLEKVGYEGGYGKYIRMKHANGYETAYGHMSAFAKGMEIGKKVRQGQVIGFVG 653 I A+GNG +EK G+ GYG ++HANGY ++Y H SA AKG+ G KVRQGQVIG+VG Sbjct: 524 IIATGNGTVEKAGWASGYGNQTLIRHANGYVSSYNHQSAIAKGVTEGSKVRQGQVIGYVG 583 Query: 654 STGQSTGPHVHYEILVNGRFVDPMRVKLPRGRSLEGPMLANFEKERDRIE 703 STG STG H+HYE++VNG VD M+V+LP G+SL G LA F ER RI+ Sbjct: 584 STGLSTGAHLHYELIVNGTKVDAMKVRLPGGKSLSGVALARFSDERKRID 633 >SMc02432 [M] COG0739 Membrane proteins related to metalloendopeptidases Sme Sinorhizobium meliloti Length = 646 Score = 344 bits (883), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 227/662 (34%), Positives = 353/662 (53%), Gaps = 61/662 (9%) Query: 64 LGHEPPLSVDGTEAAVIDRRRVSVQWFSGTILTGLCGAALIGGAVFASLDGEMTFAKVPE 123 LG PP+ DG A DRR +S++W SGT LTG+ + L+G A+FA+LDG A +P Sbjct: 11 LGDHPPILADGRRAP--DRREISMRWLSGTFLTGITSSLLMGVALFAALDGRQQLA-IPA 67 Query: 124 RVEGALR-----GAFTGNDRVVSLHKGDRLPPPSESSASRSLVRVSTVTRVGNRDVMRVR 178 AL GA DRV+S P A ++++ VST+ G ++V+R + Sbjct: 68 EAFAALDPSAPVGAAKRGDRVLS-------PNIVAKPADKTVMEVSTMIHDGEKEVVRRQ 120 Query: 179 PFIRISGNLSMTTSDLSAKIPAFNAQRLLT--DVGSDTPAAAEDPNAAAEPDAEVSFVTK 236 PF+ + L+ S P F+ + + + ++ P ++ ++EV+ T Sbjct: 121 PFVHVKMALA-ANHQTSESYPDFDPLAIFSTDEADAEAPPVKTGTIYGSDVESEVALKTV 179 Query: 237 DLGSVLPKAKLAAVVALDDVLMRVRDAANWRGSGGSVRYASLANAAADASGAGPDMRMAY 296 D L ++LD+V VR + + G+ + ASL + Sbjct: 180 DFPLNGGGFALGPSMSLDEVEENVRTNGSVL-TEGNTQVASLFYVDP----------QRF 228 Query: 297 ATEGNTSDPYAGFETRVVPENVTLLPKTKEQVTGGN-PVGERVHLVKKGDSITSILRDQG 355 A++ + D G RVV EN+++ + E +T + + + V++ I + + + G Sbjct: 229 ASDADNLDLMQGLAARVVEENMSV--SSYENITKQSIEYADDIIPVRRATPIATAMINAG 286 Query: 356 ATPDEAKAIAA---------TLGPRG--RDGGLKEGQKVRILMAPAAPGPNVRLQPYRVI 404 +A+ A LGP R G +++G++ +I+ R Sbjct: 287 YAKAQAEDAAGYLEEALGAKELGPGDVLRIGIIQKGEEAKIV---------------RAT 331 Query: 405 VANESVIEAVAALSDLGKYV-AVDVQSMNTVTETADNSSDDDEDDGSGV-RLYQSIYETA 462 + + S A+ D G+++ + + V D++ G + R+Y IY A Sbjct: 332 IYSHSRHVLTMAVDDRGRFIPGAEPAKLEAVAAAFDDTGRPVISSGHDLPRVYDGIYRAA 391 Query: 463 LRNKVPPTVIEDMVKIYSYDVDFQRKVQPGDSFDVFFAGEDEGVTSTEKTEVLYAALTVG 522 L + +I +VK+ + +VDFQ +++P DS + FF+ DE +TE +E+LY G Sbjct: 392 LSYGMNADMIALVVKLLASNVDFQAQLKPTDSLEAFFSVTDESGRATEDSELLYVNAKFG 451 Query: 523 GETKKYYRFQSSDDGLVDYYDETGKSAKKFLVRKPVNNAIMRSGFGGRRHPILGYVKMHT 582 ++YRFQ DD +DY+D+ GKS ++FL+R PV N RSGFG RRHPILG+ +MHT Sbjct: 452 DAETRFYRFQDPDDNSIDYFDKDGKSIRQFLLRNPVPNGHFRSGFGMRRHPILGFSRMHT 511 Query: 583 GVDWATAYGTPIFASGNGVLEKVGYE-GGYGKYIRMKHANGYETAYGHMSAFAKGMEIGK 641 GVDW+ GTPI A+GNGV++K G++ GGYG ++HANGY ++Y H SA AK ++ G Sbjct: 512 GVDWSAPRGTPIIAAGNGVVQKAGWDSGGYGNQTLIRHANGYVSSYNHQSAIAKSVKPGT 571 Query: 642 KVRQGQVIGFVGSTGQSTGPHVHYEILVNGRFVDPMRVKLPRGRSLEGPMLANFEKERDR 701 KV QGQVIG+VG+TG STGPH+HYE++VNG VDP+R++LP G+SL G LA FEKER+R Sbjct: 572 KVVQGQVIGWVGTTGLSTGPHLHYELIVNGNKVDPLRIRLPGGKSLGGEALAKFEKERER 631 Query: 702 IE 703 I+ Sbjct: 632 ID 633 >mlr3423 [M] COG0739 Membrane proteins related to metalloendopeptidases Mlo Mesorhizobium loti Length = 476 Score = 303 bits (776), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 166/398 (41%), Positives = 236/398 (59%), Gaps = 11/398 (2%) Query: 309 FETRVVPENVTLLPK--TKEQVTGGNPVGERVHLVKKGDSITSILRDQGATPDEAKAIAA 366 ++ ++VPENV++ P+ T +Q E + K +T D G T D+A +A Sbjct: 67 YDVKIVPENVSVSPRAATDDQAPA---FAEEIIPFTKDTDLTEAFADSGYTGDDATGMAE 123 Query: 367 TLGPRGRDGGLKEGQKVRILMAPAAPGPNVRLQPYRVIVANESVIEAVAALSDLGKYVAV 426 + LK G +R+ + V R V +++ AL D G+YV Sbjct: 124 AIAKLLNAPTLKAGTVLRVGLEVHGDAAKV----VRTSVYDKTTHIVTIALDDRGQYVPA 179 Query: 427 DVQSMNTVTETA-DNSSDDDEDDGSGVRLYQSIYETALRNKVPPTVIEDMVKIYSYDVDF 485 N TA D+SS G+ +Y IY A + + + ++K+ + VDF Sbjct: 180 QEPEPNPELLTAFDDSSAPVVVRGNLPNVYDGIYRAAYSYGMSKKMTQRLIKLLASGVDF 239 Query: 486 QRKVQPGDSFDVFFAGEDEGVTSTEKTEVLYAALTVGGETKKYYRFQSSDDGLVDYYDET 545 Q ++ P D +V F+ D +++ +E+LY + T GG T+ +YRFQ D G DY+DE Sbjct: 240 QSRLNPSDRLEVLFSQPDGDDQTSDDSELLYVSATFGGTTRNFYRFQMQD-GSTDYFDED 298 Query: 546 GKSAKKFLVRKPVNNAIMRSGFGGRRHPILGYVKMHTGVDWATAYGTPIFASGNGVLEKV 605 G SA++FL+R P+ N SGFG R+HPILGYV+MHTG DWA G+PI A+GNGV+EK Sbjct: 299 GSSAQQFLLRNPLPNGRFTSGFGARKHPILGYVRMHTGTDWAAPIGSPIIAAGNGVVEKA 358 Query: 606 GYEGGYGKYIRMKHANGYETAYGHMSAFAKGMEIGKKVRQGQVIGFVGSTGQSTGPHVHY 665 G+ GGYGK I ++HANGYET+Y H SAFAKG+ G +VRQGQVIG++G TG STGPH+HY Sbjct: 359 GWAGGYGKQIILRHANGYETSYNHQSAFAKGIAPGIRVRQGQVIGYLGQTGLSTGPHLHY 418 Query: 666 EILVNGRFVDPMRVKLPRGRSLEGPMLANFEKERDRIE 703 E++VNG VD MRV+LP G+ L+G L F++ER+RI+ Sbjct: 419 ELIVNGTKVDSMRVRLPVGKVLKGDDLVAFKRERERID 456 >CC3034 [M] COG0739 Membrane proteins related to metalloendopeptidases Ccr Caulobacter vibrioides Length = 458 Score = 215 bits (547), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 130/387 (33%), Positives = 211/387 (54%), Gaps = 44/387 (11%) Query: 341 VKKGDSITSILRDQGATPDEAKAIAATLGPRGRDGGLKEGQKVRILMAPAAPGPNVRLQ- 399 V+ G+++ ++ G P+EA+ + ATL G + ++ MA A R Q Sbjct: 79 VRPGETLQGAVQRTGVAPEEARQVVATLQ------GAIDTVNIKAGMAFEAAVAQRRSQR 132 Query: 400 -PYRVIVANESVIEAVAALSDLGKYVAVDVQSMNTVTETADNS--------SDDDEDDGS 450 P R++ G + S TV+ T D + DE + Sbjct: 133 GPARLV----------------GLSMRTSPSSTLTVSRTFDGALRLREMEEEVRDEQQVA 176 Query: 451 GVRLYQSIYETALRNKVPPTVIEDMVKIYSYDVDFQRKVQPGDSFDVFFAGEDEGVTSTE 510 + S YE+ P VI K++S+ +DF R ++ GD F + F D VT + Sbjct: 177 CGEMNGSFYESVANVGGTPAVISQAAKLFSHKIDFSRDIKEGDRFCLIF---DRKVTESG 233 Query: 511 KT----EVLYAALTVGGETKKYYRF-QSSDDGLVDYYDETGKSAKKFLVRKPVNNAIMRS 565 +T ++ YA + + +K+Y F + ++G ++DETGK+ K FL+R PV+ A + S Sbjct: 234 RTIEAGDLEYAEV----KGQKFYAFDRKGENGNSQFFDETGKNIKGFLLRTPVDGARITS 289 Query: 566 GFGGRRHPILGYVKMHTGVDWATAYGTPIFASGNGVLEKVGYEGGYGKYIRMKHANGYET 625 FG RRHPILGY + H GVD+ GTPI A+G+GV+ + GYG ++R++H+ ++T Sbjct: 290 KFGLRRHPILGYNRAHQGVDFGAGTGTPILAAGDGVVLEARRWAGYGNWLRIRHSGQWDT 349 Query: 626 AYGHMSAFAKGMEIGKKVRQGQVIGFVGSTGQSTGPHVHYEILVNGRFVDPMRVKLPRGR 685 Y H+S +AKG++ G +VRQGQV+ +VGSTG S+GPH+HYE+ + G+ V+P+ K+P+G Sbjct: 350 GYAHISRYAKGIKPGTRVRQGQVVAYVGSTGMSSGPHLHYEVWLKGQRVNPIGAKVPQGT 409 Query: 686 SLEGPMLANFEKERDRIEAQMSSRGSS 712 L G LA+F ++ RI+ ++ G++ Sbjct: 410 ILAGAELASFRSQKARIDRMLAEGGAA 436