BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0041.p (476 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb20415 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epi... 253 6e-67 CC2899 Non COG 203 9e-52 PA0333 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epime... 80 1e-14 aq_135 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epime... 74 6e-13 DR1980 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epime... 70 1e-11 >SMb20415 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases Sme Sinorhizobium meliloti Length = 429 Score = 253 bits (646), Expect = 6e-67, Method: Compositional matrix adjust. Identities = 164/445 (36%), Positives = 236/445 (53%), Gaps = 30/445 (6%) Query: 14 ILVLGASGLIGRTITDDLRARGFHVIGIARHFT-PAQKMSAADIELPVMAMDAAALTQLL 72 +LV+GASGLIG + L RG ++ + R + P+ + +EL + ++ L Sbjct: 4 VLVVGASGLIGSAVCAGLHGRGSEIVRVVRPGSAPSSHTAGKALELDLRSVGPE--DWLP 61 Query: 73 RTHEVDIVVNCLGVLQDGPGSDTSAVHRDLVARLLRAIGDSHRAIRLVHISIPGTADADR 132 +D VVNC G LQDGPG DT+AVH A L +A + R++H S G A Sbjct: 62 HLSGIDAVVNCAGTLQDGPGEDTTAVHARGPASLFKAC-EQAGVRRVIHFSAMGVDRAQP 120 Query: 133 TAFSTTKREAERLIAASGIPHAILRPGFVIAPSAYGGSAMLRALAALPVDLPAEEAATPF 192 + FS TK + + + A + ILRP V+ P AYG SA+ R LAALP LP Sbjct: 121 SPFSRTKLQGDEALMACDLDWVILRPSVVLGPGAYGASALFRGLAALPW-LPVMPNTGLL 179 Query: 193 QPVAVEDIAATIAWLAARDVADEAVRSVTWDLMQKQPISLGGVIAQFRRSFG--TAKHVR 250 Q V +ED+ T+ V A +T ++ + +S V+ +RR FG A+ V Sbjct: 180 QVVRLEDVVRTVEMF----VKPNAPSRLTLEVAGPEALSFKDVVGTYRRWFGWPAARVVN 235 Query: 251 IATPPFLIDLGARLGDLASRLGWMPPLRSTAIAELRRGVTGDPAGWMQATGIVPKTIAQA 310 + TP L +L +L D+A LGW PP RSTA E+ RG GD W++ TGI P +A Sbjct: 236 MPTP--LANLTYKLSDIAGALGWRPPTRSTAQKEIGRGAVGDNRAWVEKTGIEPAALADT 293 Query: 311 VGGRPATIQDKWFARLFLIKALIFASLVLFWVASGFIALVISYD--------AAAGILRA 362 + P ++Q++WFA+L+L+K +IF L LFW+ +G I+L Y+ AG+L Sbjct: 294 LARTPVSVQERWFAKLYLLKPVIFVVLPLFWITTGVISLTSGYEIGVDLMERGGAGVL-- 351 Query: 363 HDFPPASVGPVTVLTSLMDMSIGVLIAIRRTAALGLIAGIIASLGYMVGSAILTPDLWIE 422 GP + +L D+ IG+ IA RRT+ +GL + SL Y + L P+LW E Sbjct: 352 -------AGPSVIAGALADILIGMAIAFRRTSRIGLYGAVGLSLFYAIAGTALLPELWNE 404 Query: 423 PLGALVKTGPAIMLMLVALLMLENR 447 PLG L+K P ++L L AL +LE R Sbjct: 405 PLGPLLKIWPILVLHLAALAILEER 429 >CC2899 Non COG Length = 430 Score = 203 bits (516), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 164/442 (37%), Positives = 235/442 (53%), Gaps = 20/442 (4%) Query: 13 NILVLGASGLIGRTITDDLRARGFHVIGIARHFTPAQKMSAADIELPVMAMDAAALTQ-- 70 ++V+GA GLIG ++ L A G V+G+ R A++ P + A L Sbjct: 2 RVVVIGAYGLIGSSVVARLLADGHDVVGVGRDLVQARR------RFPALVWKHADLATFG 55 Query: 71 ----LLRTHEVDIVVNCLGVLQDGPGSDTSAVHRDLVARLLRAIGDSHRAIRLVHISIPG 126 L V VVNC G LQD P D +AVH + V RL +A ++ RA RLVHIS G Sbjct: 56 VADWLALLDGVAAVVNCAGALQDSPRDDLNAVHVEGVRRLAQAC-EAKRA-RLVHISAAG 113 Query: 127 TADADRTAFSTTKREAERLIAA-SGIPHAILRPGFVIAPSAYGGSAMLRALAALPVDLPA 185 TAF+TTK EAE L+AA + +LRPG VI P+AYGG+A+LR LA P P Sbjct: 114 VEADKPTAFNTTKHEAEALLAAMPALDWVVLRPGLVIGPAAYGGTALLRGLAGFPGFSPV 173 Query: 186 EEAATPFQPVAVEDIAATIAWLAARDVADEAVRSVTWDLMQKQPISLGGVIAQFRRSFGT 245 + Q VA +D+AA AR +A +A DL+ + ++L ++++ R G Sbjct: 174 VHGQSRVQVVATDDVAAA----VARCLAPDAPLRRRLDLVHAEAVTLTDLVSRLRGWLGF 229 Query: 246 AKHVRIATPPFLIDLGARLGDLASRLGWMPPLRSTAIAELRRGVTGDPAGWMQATGIVPK 305 I PP L + A D + LGW P+R+ A+A+LR GV G+ A + K Sbjct: 230 PAAPVIDLPPVLARITAAGADALAFLGWRSPMRTAALAQLRMGVRGE-ADDAARLALELK 288 Query: 306 TIAQAVGGRPATIQDKWFARLFLIKALIFASLVLFWVASGFIALVISYDAAAGILRAHDF 365 ++ + P+ +Q++WFAR + K LI A L FW+ SG I L + ++ A L Sbjct: 289 SLDALLAAMPSGVQERWFARAYFAKPLILACLFAFWLVSGLIGLTVGFEPAVATLTTAGV 348 Query: 366 PPASVGPVTVLTSLMDMSIGVLIAIRRTAALGLIAGIIASLGYMVGSAILTPDLWIEPLG 425 V S+ D+++ +L+A RRTAA L ++ + GY+VG A++ PDLW++PLG Sbjct: 349 GRELAVAAVVGGSVADIALALLLAHRRTAAPALKGMLLVTAGYLVGGALVRPDLWLDPLG 408 Query: 426 ALVKTGPAIMLMLVALLMLENR 447 LVK+ PA ML + AL LE R Sbjct: 409 PLVKSIPAAMLAVAALATLEER 430 >PA0333 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases Pae Pseudomonas aeruginosa Length = 423 Score = 79.7 bits (195), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 120/448 (26%), Positives = 199/448 (44%), Gaps = 39/448 (8%) Query: 13 NILVLGASGLIGRTITDDLRARGFHVIGIARH---FTPAQ-KMSAADIELPVMAMDAAAL 68 IL++GA G +GR + L A G ++ AR PA + A D+E D+ A Sbjct: 2 RILLVGAGGFVGRHLLPALLAAGHELLLTARRPPVDAPAGVRWLALDLERLAERPDSFAW 61 Query: 69 TQLLRTHEVDIVVNCLGVLQDGPGSDTSAVHR--DLVARLLRAIGDSHRAIRLVHISIPG 126 VD+++N G + D +++ R D AR L + +H A +++ IS G Sbjct: 62 PA-----GVDLLINAAGTMS----LDEASMARVQDSGARTLFDLAAAHGA-KVLQISALG 111 Query: 127 TADADRTAFSTTKREAERLIAASGIPHAILRPGFVIAPSAYGGSAMLRALAALPVDLPAE 186 AF +K A+R + GIP +LRP ++ P + + R + L Sbjct: 112 AGAHPDVAFLASKAAADRHLLELGIPALVLRPSLLLGPGGASSAWLERLSPLPLIPLLDN 171 Query: 187 EAATPFQPVAVEDIAATIAWLAARDVADEAVRSVTWDLMQKQPISLGGVIAQFRRSFGTA 246 A QP+ VED+ + LA E + + L+ Q ++ G ++ + RR+ G Sbjct: 172 RAR--LQPLHVEDLVGAV--LALLRCWPERAQVIP--LVGPQALTQGELLDELRRAQGWP 225 Query: 247 KHVRIATPPFLIDLGARLGDLASRLGWMPPLRSTAIAELRRGVTGDPAGWMQATGIVPKT 306 + + P L+D LG L R GW L + + +R DPA +A G Sbjct: 226 RGRYVVPPAALLD---ALGGLGRRAGWRT-LSPSMLKLVRHDNLADPALLDEACGYRCAP 281 Query: 307 IAQAVGGRPATIQDKWFARLFLIKALIFASLVLFWVASGFIALVISYDAAAGILRA---H 363 +A + G P + + L++ L+ A+LVL W+ + L Y IL H Sbjct: 282 LASRLLGWPQAAR----SLAALMRPLMLAALVLIWLGTLVACLGPGYGWGLRILGEAGIH 337 Query: 364 DFPPASVGPVTVLTSLMDMSIGVLIAIRRTAALGLIAGIIASLGYMVGSAILTPDLWIEP 423 +P AS+ + +L+D ++GV + +RR L+A LGY + +++ P W +P Sbjct: 338 GWP-ASL--AVIAGALLDGALGVGLLLRRWRRRALLAQFWLMLGYSLAISLILPHYWYDP 394 Query: 424 LGALVKTGPAIMLMLVALLMLENRERFR 451 A+ K I+LM+ L +L + R R Sbjct: 395 YMAVGKN---IVLMVATLWLLGDEPRTR 419 >aq_135 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases Aae Aquifex aeolicus Length = 315 Score = 74.3 bits (181), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 48/195 (24%), Positives = 87/195 (44%), Gaps = 4/195 (2%) Query: 14 ILVLGASGLIGRTITDDLRARGFHVIGIARHFTPAQKMSAADIELPVMAMDAA-ALTQLL 72 + + GA+G +GR I +L RG+ V R+ + +++ ++ ++ D ++ + L Sbjct: 3 VFITGATGFVGRHIVRELLNRGYEVHAGVRNLSKLERLFGNQVKGYIVNFDEKDSIREAL 62 Query: 73 RTHEVDIVVNCLGVL--QDGPGSDTSAVHRDLVARLLRAIGDSHRAIRLVHISIPGTADA 130 D V++ +G+L + G VH L+ + + + +S GT D Sbjct: 63 GKVNPDFVIHLIGILYEEKKKGITFERVHYGHTKNLVE-VSKGFNVKKFLFMSALGTHDE 121 Query: 131 DRTAFSTTKREAERLIAASGIPHAILRPGFVIAPSAYGGSAMLRALAALPVDLPAEEAAT 190 + + TKR AER + SG+ + I RP ++ P M + +PV + Sbjct: 122 APSRYHQTKRWAEREVINSGLNYTIFRPSIILGPEQKLFFDMYKITKYIPVVALPDFGNY 181 Query: 191 PFQPVAVEDIAATIA 205 FQPV V D+A A Sbjct: 182 QFQPVDVRDVACAYA 196 >DR1980 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases Dra Deinococcus radiodurans Length = 321 Score = 70.1 bits (170), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 71/273 (26%), Positives = 122/273 (44%), Gaps = 27/273 (9%) Query: 6 MSDDASH--NILVLGASGLIGRTITDDLRARGFHVIGIARHFTPAQKMSAADIELPVMAM 63 M++ A H ILV GASG +GR +L RG+ V+ +R K I + + Sbjct: 4 MAEQAEHPSRILVTGASGFVGRATLAELTRRGYEVVAGSRQ----GKGVGRGIGIKLDVT 59 Query: 64 DAAALTQLLRTHEVDIVVNCLGVLQDGPGSDTSAVHRDLVARLLRAIGD-------SHRA 116 ++ Q L+ + V++ +G++ + VH + +L A+ D +H+ Sbjct: 60 SEKSVRQALQDVQPAAVIHLVGIIAEKGKQTFERVHIEGTRHVLDALRDYDAARQQAHKG 119 Query: 117 --------IRLVHISIPGTADADRTAFSTTKREAERLIAASGIPHAILRPGFVIA-PSAY 167 R +H+S G +A+S +K EAE L+ SG+P I RP + + Sbjct: 120 DEMERPHPTRYLHMSALGADVLSPSAYSWSKGEAEGLVRLSGLPWTIFRPSLIFGVGDDF 179 Query: 168 GGSAMLRALAALPVDLPAEEAATPFQPVAVEDIAATIAWLAARDVADEAVRSVTWDLMQK 227 G + ++A PV + PF+P++VED+A A V E V + + L Sbjct: 180 FGRVLKNLVSAAPVVPQIGDGQFPFRPISVEDVALAFAEAL---VKPETVGQI-YALTGP 235 Query: 228 QPISLGGVIAQFRRSFGTAKHVRIATPPFLIDL 260 Q + ++A +++ G K V + P L+DL Sbjct: 236 QEFTFKELLALEQQALGQQKKV-VPVPQKLMDL 267