BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0001.0038.p         (416 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Rv3170 [E] COG1231 Monoamine oxidase Mtu Mycobacterium tuberculo...    65   3e-10
MT3259 [E] COG1231 Monoamine oxidase MtC Mycobacterium tuberculo...    63   1e-09

>Rv3170 [E] COG1231 Monoamine oxidase Mtu Mycobacterium tuberculosis H37Rv
          Length = 448

 Score = 65.1 bits (157), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 132/467 (28%), Positives = 185/467 (39%), Gaps = 78/467 (16%)

Query: 1   MTSLPSTIDVAIIGAGAAGLGAANALKDSGLSTIVLEARDRLGGRAHTIQAAPDVVFDVG 60
           MT+ P T+DV ++GAG AGL AA  L   G   +V E RDR+GGR+ T + A  V  D+G
Sbjct: 1   MTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVA-GVPADMG 59

Query: 61  CGWLHSADRNSFVGIARQLNFELN------KDLPPWR--ERAYGEAFPQAARDDFTHA-- 110
             ++    +++ + +A +L           +++  WR   R+Y    P+ +         
Sbjct: 60  GSFI-GPTQDAVLALATELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGR 118

Query: 111 LDQFYDRIEQ----AAQQGKDRPASLYLEPGNRWNPMIDAISTYVN----------GCEL 156
           L   ++RI +    AA     R   L       W  ++ A S+  N          GCE 
Sbjct: 119 LRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSSSRNLMAIMTRVTWGCEP 178

Query: 157 DQVSILDVDAYEDTDINWRVRRGYG---VLVAAYGAQ---VP-----------------V 193
           D VS+L    Y        VR   G   +L    GAQ   VP                 V
Sbjct: 179 DDVSMLHAARY--------VRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARV 230

Query: 194 ALNCEVRLIDHSGKRIRIETSRGVLEADKVIVTVPTNLIADEAIRFSPALPDKLDA-ARG 252
            LN  VR ID  G  + + + +G  EA  VIV +P       AI F P LP +    A  
Sbjct: 231 LLNAAVRRIDRHGAGVTVTSDQGQAEAGFVIVAIPPA--HRVAIEFDPPLPPEYQQLAHH 288

Query: 253 LPLGLADKVTLALAEPEALPKEGNLRGATMRTE---MGTYHIRPF--GQPCIEGFFGGRF 307
            P G   K   A + P    +     G  +  E     T+ + P   G   + GF   R 
Sbjct: 289 WPQGRLSKAYAAYSTP--FWRASGYSGQALSDEAPVFITFDVSPHADGPGILMGFVDARG 346

Query: 308 ARQLENAGDGAIAAHSIDEIVSFLGNDFRRKLQPLS--ESRWAHDPFARGSYSHAL-PGH 364
              L       I     D +  F        L PL   + RW  + FA G  + A+ PG 
Sbjct: 347 FDSLP------IEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGS 400

Query: 365 ADKRA-VLAAPVDGRLFFAGEATSPEFFSTAHGARDSGERAAKEVVA 410
             K    L  PV G + +A   T+ E+     GA  SG+RAA EV A
Sbjct: 401 WTKYGHWLREPV-GPIHWASTETADEWTGYFDGAVRSGQRAAAEVAA 446


>MT3259 [E] COG1231 Monoamine oxidase MtC Mycobacterium tuberculosis
           CDC1551
          Length = 454

 Score = 62.8 bits (151), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 131/467 (28%), Positives = 185/467 (39%), Gaps = 78/467 (16%)

Query: 1   MTSLPSTIDVAIIGAGAAGLGAANALKDSGLSTIVLEARDRLGGRAHTIQAAPDVVFDVG 60
           +T+ P T+DV ++GAG AGL AA  L   G   +V E RDR+GGR+ T + A  V  D+G
Sbjct: 7   VTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVA-GVPADMG 65

Query: 61  CGWLHSADRNSFVGIARQLNFELN------KDLPPWR--ERAYGEAFPQAARDDFTHA-- 110
             ++    +++ + +A +L           +++  WR   R+Y    P+ +         
Sbjct: 66  GSFI-GPTQDAVLALATELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGR 124

Query: 111 LDQFYDRIEQ----AAQQGKDRPASLYLEPGNRWNPMIDAISTYVN----------GCEL 156
           L   ++RI +    AA     R   L       W  ++ A S+  N          GCE 
Sbjct: 125 LRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSSSRNLMAIMTRVTWGCEP 184

Query: 157 DQVSILDVDAYEDTDINWRVRRGYG---VLVAAYGAQ---VP-----------------V 193
           D VS+L    Y        VR   G   +L    GAQ   VP                 V
Sbjct: 185 DDVSMLHAARY--------VRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARV 236

Query: 194 ALNCEVRLIDHSGKRIRIETSRGVLEADKVIVTVPTNLIADEAIRFSPALPDKLDA-ARG 252
            LN  VR ID  G  + + + +G  EA  VIV +P       AI F P LP +    A  
Sbjct: 237 LLNAAVRRIDRHGAGVTVTSDQGQAEAGFVIVAIPPA--HRVAIEFDPPLPPEYQQLAHH 294

Query: 253 LPLGLADKVTLALAEPEALPKEGNLRGATMRTE---MGTYHIRPF--GQPCIEGFFGGRF 307
            P G   K   A + P    +     G  +  E     T+ + P   G   + GF   R 
Sbjct: 295 WPQGRLSKAYAAYSTP--FWRASGYSGQALSDEAPVFITFDVSPHADGPGILMGFVDARG 352

Query: 308 ARQLENAGDGAIAAHSIDEIVSFLGNDFRRKLQPLS--ESRWAHDPFARGSYSHAL-PGH 364
              L       I     D +  F        L PL   + RW  + FA G  + A+ PG 
Sbjct: 353 FDSLP------IEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGS 406

Query: 365 ADKRA-VLAAPVDGRLFFAGEATSPEFFSTAHGARDSGERAAKEVVA 410
             K    L  PV G + +A   T+ E+     GA  SG+RAA EV A
Sbjct: 407 WTKYGHWLREPV-GPIHWASTETADEWTGYFDGAVRSGQRAAAEVAA 452